Results 141 to 150 of about 2,071,364 (242)
ABSTRACT Purpose The rising prevalence of obesity introduces challenges in surgical contexts, including endoscopic sinus surgery (ESS) for chronic rhinosinusitis with nasal polyps (CRSwNP). However, the impact of obesity on ESS outcomes remains underexplored. This study aims to evaluate the association between obesity and surgical complexity, operative
Hen Chaushu +6 more
wiley +1 more source
Clinical and Lung Function Outcomes After Anti-IgE or Anti-IL5 Therapy in Severe Asthma. [PDF]
AlShareef S, McDonald CF, Lee J.
europepmc +1 more source
ABSTRACT Objective Chronic rhinosinusitis with nasal polyps (CRSwNP) is a persistent inflammatory condition often associated with other type‐2 diseases. Dupilumab, a monoclonal antibody targeting IL‐4Rα, has revolutionized the treatment of severe CRSwNP.
Pietro Orlando +17 more
wiley +1 more source
Inflammatory Shift in Chronic Rhinosinusitis Amidst Guangzhou's Urbanization (2000–2018)
ABSTRACT Background Chronic rhinosinusitis (CRS) exhibits temporal and geographic diversity in pathological endotypes with progressive eosinophilic infiltration, while the underlying causes remain unclear. Current pathological endotypes determination relies on mean cell count per high‐power field, requiring accuracy optimization.
Ning Kang +16 more
wiley +1 more source
The anti-IgE monoclonal antibody omalizumab as adjuvant treatment in desensitization to carboplatin in patients with ovarian cancer. [PDF]
Vultaggio A +12 more
europepmc +1 more source
ABSTRACT Objective Budesonide is a corticosteroid with unique pharmacokinetic and pharmacodynamic properties that has been a frontline treatment for patients with allergic rhinitis (AR) and chronic rhinosinusitis (CRS) since the 1990s. As research on budesonide continues to produce new insights, our aim was to synthesize recent investigations and ...
David W. Kennedy +2 more
wiley +1 more source
6-O-angeloylplenolin inhibits anti-IgE-stimulated human mast cell activation via suppressing calcium influx and ERK phosphorylation. [PDF]
Yu Y +8 more
europepmc +1 more source
Turbinoplasty Versus Medical Treatment for Allergic Rhinitis: A Systematic Review and Meta‐Analysis
ABSTRACT Objective Allergic rhinitis is a common chronic condition affecting up to 30% of adults worldwide, with nasal obstruction being the most bothersome symptom. Inferior turbinate hypertrophy is a major contributor to nasal obstruction in allergic rhinitis, and surgical reduction techniques have been developed for cases refractory to medical ...
Noof Albannai +12 more
wiley +1 more source

