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Omalizumab: Anti-IgE Therapy in Allergy
Current Allergy and Asthma Reports, 2011Omalizumab is a humanized, monoclonal anti-IgE antibody that binds specifically to circulating IgE molecules, thus interrupting the allergic cascade. Omalizumab has been shown to be highly effective in treating children and adults with moderate to severe allergic asthma.
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Natural And Recombinant ANTI-IgE Autoantibodies
1996Since the first description of anti-IgE autoantibodies by Williams et al. in 19721, these antibodies have remained a much disputed subject. Most immunologists considered such natural autoantibodies as low affinity antibodies of no importance. Despite the fact that Manning et al.
B M, Stadler +5 more
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Clinical Reviews in Allergy & Immunology, 2005
Bruce, Bochner, Sarbjit, Saini
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Bruce, Bochner, Sarbjit, Saini
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Anti-IgE therapy in allergic disease
Current Opinion in Pediatrics, 2004Recombinant monoclonal humanized anti-IgE has put forward a fundamentally new concept for the control of allergic disorders. This review will present recent data from clinical studies with anti-IgE in asthma, allergic rhinitis, and food allergy and will examine the place of anti-IgE among current therapeutic options for the treatment of asthma.Therapy ...
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Structure-based functional mechanisms and biotechnology applications of anti-CRISPR proteins
Nature Reviews Molecular Cell Biology, 2021Ning Jia, Dinshaw J Patel
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Targeting cancer-promoting inflammation — have anti-inflammatory therapies come of age?
Nature Reviews Clinical Oncology, 2021Michael Karin
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Anti-obesity drug discovery: advances and challenges
Nature Reviews Drug Discovery, 2021Timo D Müller +2 more
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