Results 81 to 90 of about 2,071,364 (242)

Causal correlations between inflammatory proteins and heart failure: A two‐sample Mendelian randomization analysis

ESC Heart Failure, Volume 12, Issue 2, Page 1374-1385, April 2025.
Abstract Aims Inflammation plays a critical role in both the development and progression of heart failure (HF), which is a leading cause of morbidity and mortality worldwide. However, the causality between specific inflammation‐related proteins and HF risk remains unclear.
Xian‐Guan Zhu, Gui‐Qin Liu, Ya‐Ping Peng, Li‐Ling Zhang, Xian‐Jin Wang, Liang‐Chuan Chen, Yuan‐Xi Zheng, Xue‐Jun Xiang, Rui Qiao, Xian‐He Lin   +9 more
wiley   +1 more source

Anti-IgE Antibodies

, 2017
The present invention relates to the area of improved anti-IgE antibodies and antigen binding agents, and compositions thereof, which target IgE, for instance: for use in treating disorders caused by IgE (such as allergic responses, or certain autoimmune
Adams, Ralph, Davies, Anna Marie; id_orcid, Ceska, Thomas Allen, McDonnell, James Michael; id_orcid, Westwood, Marta Katarzyna, Henry, Alistair James, Liu, Xiaofeng, Sutton, Brian John   +7 more
core   +5 more sources

KBG syndrome: A scoping review of electroclinical features of patients with epilepsy

Epileptic Disorders, EarlyView.
Abstract Background and Objectives KBG syndrome is a rare autosomal developmental disorder caused by pathogenic variants of the ANKRD11 gene. This scoping review aimed to explore all current literature data regarding clinical and electroencephalographic features of patients with KBG syndrome and epilepsy. Materials and Methods We conducted a literature
Stefania Kalampokini, Evripidis Pityrigkas, Zoi Kallia, Georgia Pepe, Antonis Frontistis, Dimitrios Profer, Vasilios Kimiskidis   +6 more
wiley   +1 more source

Anti-Plasmodium immunoglobulin E in children of Urabá (Colombia) according to the presence of malaria = Inmunoglobulina E anti-Plasmodium en niños de Urabá (Colombia) según la presencia de malaria

Iatreia, 2013
Problem: We are not aware of studies in Colombia on levels of specific IgE in children without malaria and only one is available in children with uncomplicated malaria.
Jaime Carmona-Fonseca
doaj  

Phenotypes and endotypes in asthma-practical approach

Indian Journal of Allergy Asthma and Immunology
Asthma is a complex heterogeneous inflammatory airway disorder. Inflammation is usually accompanied by an increase in airway smooth muscle mass, thickening of subepithelial lamina reticularis, matrix deposition in the airway walls, an increase in ...
P.C. Kathuria, Manisha Rai
doaj   +1 more source

Subtyping of Type 1 Diabetes as Classified by Anti-GAD Antibody, IgE Levels, and Tyrosine kinase 2 (TYK2) Promoter Variant in the Japanese

EBioMedicine, 2017
Objective: Type 1 diabetes (T1D) is known to be caused by Th1 cell-dependent autoimmunity. Recently, we reported that TYK2 promoter variant serves as a putative virus-induced diabetes susceptibility gene associated with deteriorated interferon-dependent ...
Keiichiro Mine, Kanako Hirakawa, Shiori Kondo, Masae Minami, Akira Okada, Nobutaka Tsutsu, Yasushi Yokogawa, Yumi Hibio, Fumiko Kojima, Shuji Fujimoto, Hironori Kurisaki, Keizo Anzai, Yasunobu Yoshikai, Seiho Nagafuchi   +13 more
doaj   +1 more source

Enu mouse mutagenesis: generation of mouse mutants with aberrant plasma IgE levels. [PDF]

, 2001
peer reviewedBACKGROUND: The ENU Mouse Mutagenesis Project aims at a large-scale, systematic production of mouse mutants using the alkylating agent ethyl-nitrosourea (ENU).
Wolf, A., Behrendt, Heidrun, Alessandrini, Francesca, Behrend, H., Ring, J., Wolf, Alexander, Ring, Johannes, Jakob, T., Hrabe de Angelis, M., Jakob, Thilo, Alessandrini, F., BALLING, Rudi, Wolf, Eckhard, Behrendt, H., Hrabé de Angelis, Martin, Wolf, E., Balling, R., Balling, Rudolf, Alessandrini, F. ; Jakob, T. ; Wolf, A. ; Wolf, E. ; Balling, R. ; Hrabé de Angelis, M. ; Ring, J. ; Behrend, H., Alessandrini, Francesca;Jakob, Thilo;Wolf, Alexander;Wolf, Eckhard;Balling, Rudolf;de Angelis, Martin Hrabe;Ring, Johannes;Behrendt, Heidrun   +19 more
core   +1 more source

Does age influence diagnostic outcomes in an adult cohort referred to a first‐seizure clinic?

Epilepsia, EarlyView.
Abstract Objective The aging Danish population is associated with increasing morbidity and healthcare utilization. This study examines age‐related differences in resource utilization and diagnostic outcomes between older (65–95 years) and younger adults (18–64 years) evaluated for suspected epilepsy, including clinical management, diagnostic yield, and
Anne Line Lund Birkmose, Corinna Lackmann, Lars Hageman Pinborg, Kimmo Jensen   +3 more
wiley   +1 more source

Omalizumab as a long-term treatment for patients with severe asthma. Is it safe?: A ten-year study

Egyptian Journal of Chest Disease and Tuberculosis
Background anti-IgE (Omalizumab) is one of the targeted therapies for severe bronchial asthma. Its real-life safety is still under scrutiny.The aim of the study was to evaluate the persistent efficacy and safety of Omalizumab as a long-term treatment of ...
Mohamed Habeb, Abeer Elhawary, Mohamed S Hamed, Niveen E Zayed   +3 more
doaj   +1 more source

Current and future applications of the anti-IgE antibody omalizumab

, 2008
Cristoforo Incorvaia1, Marina Mauro2, Gian Galeazzo Riario-Sforza1,Franco Frati3, Francesco Tarantini4, Maurizio Caserini41Allergy/Pulmonary rehabilitation, ICP Hospital, Milan, Italy; 2Allergy Unit, Sant’Anna Hospital, Como, Italy; 3University
Maurizio Caserini, Franco Frati, Francesco Tarantini, Marina Mauro, Gian Galeazzo Riario-Sforza, Cristoforo Incorvaia   +5 more
core