Results 1 to 10 of about 1,244 (134)

A randomised, double‐blinded, controlled trial to determine the efficacy of combined therapy of oclacitinib and marine oil extract PCSO‐524 in dogs with atopic dermatitis

Veterinary Dermatology, Volume 34, Issue 6, Page 523-531, December 2023., 2023
Background – Polyunsaturated fatty acids (PUFA) can be beneficial in the management of canine atopic dermatitis (cAD). A commercial product PCSO‐524 containing PUFA has demonstrated anti‐inflammatory effects in dogs. Hypothesis/Objectives – To evaluate the efficacy of PCSO‐524, in combination with oclacitinib in dogs with cAD.
Takeo Nishiyama, Masashi Kusakabe, Ichiro Imanishi, Tadashi Hisano, Teruyasu Fukamachi, Norihito Taguchi, Keita Iyori, Yun‐Hsia Hsiao   +7 more
wiley   +1 more source

Histopathological characterisation of trunk‐dominant canine pemphigus foliaceus, and comparison with classic facial and insecticide‐triggered forms

Veterinary Dermatology, Volume 34, Issue 5, Page 425-440, October 2023., 2023
Background – While the clinical features were described recently, the histopathological characterisation of trunk‐dominant canine pemphigus foliaceus (PF) is lacking, and whether it differs from classic facial or insecticide‐triggered PF is unknown. Hypothesis/Objectives – This study describes the histopathological findings of trunk‐dominant PF, and ...
Natalie Katharina Yvonne Gedon, Petra Bizikova, Thierry Olivry, Ekaterina Mendoza‐Kuznetsova, Ursula Oberkirchner, James Benjamin Robertson, Keith Emerson Linder   +6 more
wiley   +1 more source

Cytokine transcriptome profiling in acute experimental canine atopic dermatitis skin lesions after IL‐31 inhibition with lokivetmab

Veterinary Dermatology, Volume 34, Issue 4, Page 327-338, August 2023., 2023
Background – The caninised monoclonal antibody lokivetmab (LKV), directed at interleukin (IL)‐31, is very effective at controlling pruritus in most dogs with atopic dermatitis (AD). However, evidence exists that IL‐31 is not required for the induction of acute allergic skin inflammation, which might explain why this treatment is less efficacious in ...
Chie Tamamoto‐Mochizuki, Natalie Crawford, Jordan M. Eder, Andrea J. Gonzales, Thierry Olivry   +4 more
wiley   +1 more source

Cutaneous microRNA expression in healthy Labrador and Golden retrievers and retrievers with allergic and inflammatory skin diseases

Veterinary Dermatology, Volume 32, Issue 4, Page 331-e92, August 2021., 2021
Background MicroRNAs (miRNA) are short, single‐stranded RNA molecules that regulate gene expression in a post‐transcriptional manner. Their expression is proposed to be tissue‐specific and alterations in miRNA expression have been detected in many diseases. Objective To compare miRNA expression in the skin of healthy Labrador and golden retrievers, and
Marie Isabel Morlang, Karin Weber, Wolf von Bomhard, Ralf S. Mueller   +3 more
wiley   +1 more source

Comportamento anti-inflamatório da IL-6 nos derrames pleurais pós-revascularização do miocárdio

Revista Portuguesa de Pneumologia, 2007
AbstractIntroduction: The local inflammatory reaction as-pects of pleural behaviour post-coronary artery bypass graft surgery (PCABG) are not completely evident, demanding further study and observation.Aim: To evaluate the behaviour of some cytokines and the possible anti-inflammatory activity of IL-6 (a protein involved in cortisone synthesis) on ...
Chibante,António M S, Vaz,Marcelo C, Vargas,Francisco Suzo   +2 more
openaire   +3 more sources

Role of circulating fibrocytes in the diagnosis of acute appendicitis

BJS Open, Volume 4, Issue 6, Page 1256-1265, December 2020., 2020
The circulating fibrocyte percentage is increased in patients with acute appendicitis. This may improve diagnostics, and reduce unnecessary radiation exposure and surgical operations. Circulating fibrocyte percentage may help in diagnosis of acute appendicitis. Background Improved diagnostic biomarkers are required for acute appendicitis.
M. A. Zarog, D. P. O'Leary, M. G. Kiernan, J. Bolger, P. Tibbitts, S. N. Coffey, A. Lowery, G. J. Byrnes, C. Peirce, C. P. Dunne, J. C. Coffey   +10 more
wiley   +1 more source

Topical treatment of equine sarcoids with imiquimod 5% cream or Sanguinaria canadensis and zinc chloride – an open prospective study

Veterinary Dermatology, Volume 31, Issue 6, Page 471-e126, December 2020., 2020
Background – Equine sarcoids are the most prevalent skin neoplasm in horses worldwide. Although several treatments are available, none are consistently effective and recurrence is common. Objectives – To evaluate the efficacy and safety of topical imiquimod 5% cream and Sanguinaria canadensis + zinc chloride for treatment of equine sarcoids and ...
Carina M. Pettersson, Hans Broström, Patrice Humblot, Kerstin E. Bergvall   +3 more
wiley   +1 more source

Simulated model of RAPID concept: highlighting innate inflammation and liver regeneration

BJS Open, Volume 4, Issue 5, Page 893-903, October 2020., 2020
The mechanism of RAPID‐associated liver regeneration and its regulation remains unclear. A RAPID model in rats was developed involving cold ischaemia and reperfusion of the selected future liver remnant, portal vein ligation of the remaining segments during step I, and resection of the deportalized lobes during step II.
J. H. Shi, X. Yan, S. J. Zhang, P. D. Line   +3 more
wiley   +1 more source

Physiological performance and inflammatory markers as indicators of complications after oesophageal cancer surgery

BJS Open, Volume 4, Issue 5, Page 840-846, October 2020., 2020
C‐reactive protein concentration and peak oxygen uptake are collective independent risk factors that can account for over half of major morbidity following oesophagectomy for oesophageal cancer. A composite risk score, the Combined Inflammatory and Physiology Score (CIPS) (range 0–2), predicted major morbidity (17·9 per cent in patients with a CIPS of ...
A. G. M. T. Powell, C. Eley, T. Abdelrahman, A. H. Coxon, C. Chin, I. Appadurai, R. Davies, D. M. Bailey, W. G. Lewis   +8 more
wiley   +1 more source

Immunotherapy using pullulan‐conjugated Der f 2 allergen in canine atopic dermatitis: An anti‐inflammatory agent‐sparing approach

Veterinary Dermatology, Volume 36, Issue 4, Page 443-452, August 2025.
Background – Allergen immunotherapy is used as aetiological treatment for canine atopic dermatitis (cAD). Objective – To assess the anti‐inflammatory agent‐sparing effect over 1 year of immunotherapy using pullulan‐conjugated recombinant Der f 2 (rDf2‐P). Conclusions and Clinical Relevance – Der f 2‐P immunotherapy can lead to a rapid reduction in anti‐
Masahiko Nagata, Jin Kozakai, Aya Yoshida, Kana Kameyama, Hiromi Oboso, Hisanori Muto, Shoji Ogino, Toshihiro Tsukui   +7 more
wiley   +1 more source