Results 301 to 310 of about 2,175,618 (339)

Functional Hydrogel for Modulating Lipid Droplets and Neuroinflammation in Head Injury

Advanced Functional Materials, EarlyView.
After TBI, elevated cholesterol levels in activated microglia lead to the accumulation of cholesterol esters in lipid droplets, exacerbating neuroinflammation. A β‐cyclodextrin‐conjugated GelMA (βCD‐GelMA) hydrogel is developed to promotes cholesterol efflux and reduces LDL influx, thereby alleviating intracellular cholesterol and lipid droplet buildup.
Feixiang Chen, Yvonne Shen, Yutong Shao, Tenghuan Ge, Haowen Qiao, Shangzhou Xia, Yafei Qu, Yuanpu Chiu, Ying Qin, Zhen Zhao   +9 more
wiley   +1 more source

Reconfigurable Nucleic Acid Nanoparticles with Therapeutic RNAi Responses to Intracellular Disease Markers

Advanced Functional Materials, EarlyView.
Many known diseases arise from dysregulated gene expression, and differentially expressed genes can serve as biomarkers to distinguish diseased cells from healthy tissues. In this study, reconfigurable nucleic acid nanoparticles (recNANPs) are introduced that can detect overexpressed cancer biomarkers and subsequently release RNAi inducers to silence ...
Yelixza I. Avila, Anh Ha, Morgan R. Chandler, Nathalia Leal Santos, Taejin Kim, Hannah S. Newton, Marina A. Dobrovolskaia, Kirill A. Afonin   +7 more
wiley   +1 more source

Formulation of zein nanoparticles for augmenting the anti-inflammatory activity of dexketoprofen. [PDF]

Front Pharmacol
El Hassab MA, Ibrahim MH, Abdel Mageed SS, Mahmoud AMA, Othman Ahmed ZS, Mosallam S, Abdelbari MA, Khaleel EF, El Hasab MA, Elsayyad A, Allam S, Eltabeeb MA, Negmeldin AT, Eldehna WM, Albash R.   +14 more
europepmc   +1 more source

FeDSNP‐Pa Nanoassemblies: A Triple‐Action Therapeutic Strategy Targeting Oxidative Stress, Inflammation, and Pyroptosis for Retinal Ganglion Cell Protection in Glaucoma

Advanced Functional Materials, EarlyView.
FeDSNP‐Pa, a metallized nanoparticle loaded with sodium pyruvate (Pa), exerts triple therapeutic effects by scavenging reactive oxygen species (ROS), suppressing inflammatory responses, and inhibiting pyroptosis signaling pathways. This multifunctional neuroprotective strategy protecting retinal ganglion cells (RGCs) from elevated intraocular pressure ...
Yukun Wu, Xue Li, Tong Wu, Dan Ji, Yugang Bai, Xuezhi Zhou   +5 more
wiley   +1 more source

Synthesis of novel phenoxyacetohydrazide compounds and evaluation therapeutic potential exhibit as anti-inflammatory and anti-angiogenic. [PDF]

PLoS One
Mohammed YHI, Shntaif AH, Alghamdi S, Mansour AA, Qusty NF, Sindi AS, Babalghith AO, Bamagous GA, Abu-Seer EA.   +8 more
europepmc   +1 more source

Correction: Formulation of zein nanoparticles for augmenting the anti-inflammatory activity of dexketoprofen. [PDF]

Front Pharmacol
El Hassab MA, Ibrahim MH, Abdel Mageed SS, Mahmoud AMA, Othman Ahmed ZS, Mosallam S, Abdelbari MA, Khaleel EF, El Hasab MA, Elsayyad A, Allam S, Eltabeeb MA, Negmeldin AT, Eldehna WM, Albash R.   +14 more
europepmc   +1 more source

Green synthesis of new chiral amino acid urea derivatives and evaluation of their anti-inflammatory activity. [PDF]

RSC Adv
Mehrez S, Absi S, Hamdi A, Marque S, Bouraoui A, Kacem Y, Kraiem J.   +6 more
europepmc   +1 more source

Applicability of <i>Hibiscus sabdariffa</i> L. Extract With Anti-Inflammatory Potential in Human Health: A Review. [PDF]

Food Sci Nutr
Nogueira da Cruz ACS, Madruga Mesquita MJTA, Dantas GKR, Silva ER, Falcone De Oliveira VC, Rezende HM, Frota GM, Cavalcante M, Garcês JRC, Souza de Andrade M, Cartagenes MDSS.   +10 more
europepmc   +1 more source

Anti-Inflammatory Saponins From an Edible Aquatic Plant Nymphoides hydrophylla. [PDF]

Phytochem Anal
Chen CY, Cheng TP, Hwang TL, Hou YS, Salendra L, Ke TY, Cheng YB.   +6 more
europepmc   +1 more source