Results 121 to 130 of about 149 (149)
ABSTRACT Background & Aims Previous results showed that combined treatment of biologics and exclusive enteral nutrition (EEN) brought moderate‐to‐severe Crohn's disease patients significant improvements in clinical and endoscopic outcomes. Despite its essential role and favorable safety profile, EEN in the treatment of adult Crohn's disease is ...
Jian Kang+12 more
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Pediatric Autoimmune Pancreatitis: Clinical Findings and Outcomes in Sweden
ABSTRACT Introduction Pediatric autoimmune pancreatitis (AIP) is a rare form of pancreatitis in children with poorly understood pathophysiology. It is a recognized risk factor for chronic pancreatitis in approximately 4% of pediatric cases. This study aims to describe the demographics, clinical characteristics, and outcomes of a large Swedish cohort of
Miroslav Vujasinovic+9 more
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Computational Drug Repositioning in Cardiorenal Disease: Opportunities, Challenges, and Approaches
PROTEOMICS, EarlyView.
Paul Perco+7 more
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Dissecting Microscopic Colitis Immunopathophysiology: Insights From Basic Research
ABSTRACT Microscopic colitis is an inflammatory bowel disease (IBD) comprising two clinically undiscernible entities: collagenous colitis and lymphocytic colitis. Collagenous colitis associates with HLA genes and displays a Th1/Tc1–Th17/Tc17 profile with pericryptal myofibroblast activity, water malabsorption and secondary fluid loss due to altered ...
Andreas Münch+1 more
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Differences in the Fecal Metabolome of Autoimmune Pancreatitis Patients
ABSTRACT Background Chronic pancreatitis is a risk factor for pancreatic cancer. Autoimmune pancreatitis is a unique form of chronic pancreatitis that is primarily characterized by its immune mediate etiology, clinically resembling pancreatic cancer, yet uniquely responsive to steroid treatment.
Vladyslav Dovhalyuk+5 more
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The chemistry of non-steroidal anti-inflammatory agents [PDF]
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Pharmacokinetics of Non‐Steroidal Anti‐Inflammatory Agents
Australian and New Zealand Journal of Medicine, 1978Summary: Pharmacokinetics of non‐steroidal anti‐inflammatory agents. G. D. Champion and G. G. Graham, Aust. N.Z. J. Med., 1978, 8, Suppl. 1, pp 94–100. The non‐steroidal anti‐inflammatory drugs (NSAID) are well absorbed from the gastrointestinal tract. The only known exception is aspirin.
Garry G. Graham, G. D. Champion
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The regulatory control of non-steroidal anti-inflammatory agents
European Journal of Clinical Pharmacology, 1981The number of marketed non-steroidal anti-inflammatory agents varies widely from one European country to another, partly as a consequence of differing regulatory policies. During a four-year period, nine of 18 applications to market such drugs in the Netherlands failed; the remaining nine compounds were all licenced; in all, 22 single drug entities of ...
I. Lunde, M. N. G. Dukes
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Non Steroidal Anti-Inflammatory and Anti-Allergy Agents
Current Medicinal Chemistry, 2002Non steroidal anti-inflammatory drugs (NSAIDs) are among the most commonly used for inflammation therapy. The major drawback in using the NSAIDs is in their tendency to cause gastrointestinal toxicity. Since the roles of arachidonic acid (A.A) metabolites, as leukotrienes (Lts), prostaglandins (PGs) and thromboxanes (TXA(2)) as mediators of the ...
Christos Kontogiorgis+1 more
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Comparative toxicity of non-steroidal anti-inflammatory agents
Pharmacology & Therapeutics, 1994Comparative toxicity of non-steroidal anti-inflammatory drugs was assessed using the Stanford Toxicity Index consisting of weighted symptoms, laboratory abnormalities and hospitalizations in 2976 consecutively enrolled rheumatoid arthritis patients from eight data bank centers with 27,936 patient-years of observation.
Dena R. Ramey+3 more
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