Results 121 to 130 of about 96,642 (272)

Access to Highly Functional and Polymerizable Carbonate‐Drug Conjugates

open access: yesChemSusChem, EarlyView.
A generic protocol for drug‐functionalized and carbon dioxide‐based six‐membered cyclic carbonates has been developed. These functional carbonates can be designed for effective ring‐opening polymerization to forge polycarbonates that support a controllable amount of a given drug and additional functionality, opening up complementary strategies for ...
Wangyu Shi   +5 more
wiley   +1 more source

Obliterative portal venopathy: A neglected and probably misdiagnosed disease with peculiar etiology in South America

open access: yesJGH Open, Volume 6, Issue 12, Page 904-909, December 2022., 2022
Classically described in the group of non‐cirrhotic portal hypertension, obliterative portal venopathy (OPV) causes are still unknown. Our aim is to describe the characteristics of 43 OPV patients and potential risk factors. Clinically significant portal hypertension was found in 28% of cases. The most frequent indication for liver biopsy was elevation
Vinícius Nunes   +7 more
wiley   +1 more source

Interest of hair tests to discriminate a tail end of a doping regimen from a possible contamination in case of challenging an anti‐doping rule violation. V. Case reports involving trimetazidine, a drug where the concentration after a single 20 mg dose has been established

open access: yesDrug Testing and Analysis, EarlyView.
From ingestion to hair incorporation Abstract The identification of trimetazidine, a medicine used for treating stable angina pectoris and for preventing angina attacks, has been recently observed in doping cases involving high profile athletes from various countries over the world.
Pascal Kintz   +2 more
wiley   +1 more source

Chronic steroid use: An overlooked impact on patients with inflammatory bowel disease

open access: yesJGH Open, Volume 6, Issue 12, Page 910-914, December 2022., 2022
Steroids have long been used in inducing remission of inflammatory bowel disease (IBD), but there is controversy about whether IBD patients should be on chronic steroids for maintenance therapy. In this retrospective study, we aim to identify the complications of chronic steroid use in patients with IBD.
Kristen L Farraj   +7 more
wiley   +1 more source

Skeletal Muscle Memory: An Update From the Antidoping Perspective

open access: yesDrug Testing and Analysis, EarlyView.
ABSTRACT This narrative review explores the concept of muscle memory, focusing on the physiological and biochemical mechanisms underlying information retention in skeletal muscle tissue as it relates to antidoping. The discussion encompasses the role of satellite cells (SCs) in myonuclei recruitment, resulting in increased myonuclear density and ...
Claire Traversa
wiley   +1 more source

Empirical Equilibria in Agent-based Economic systems with Learning agents [PDF]

open access: yesarXiv
We present an agent-based simulator for economic systems with heterogeneous households, firms, central bank, and government agents. These agents interact to define production, consumption, and monetary flow. Each agent type has distinct objectives, such as households seeking utility from consumption and the central bank targeting inflation and ...
arxiv  

Impact of Menstrual Cycle and Oral Contraceptives on Haematological and Inflammatory Biomarkers in Highly Trained Female Athletes

open access: yesDrug Testing and Analysis, EarlyView.
In highly trained female athletes, haematological and inflammatory biomarkers were found to be independent of menstrual cycle phase, but oral contraceptive use increased transferrin, reticulocyte count and triglycerides and decreased interleukin‐6.
Katia Collomp   +12 more
wiley   +1 more source

Design and Synthesis of New Non-Steroidal Anti-inflammatory Agents with Expected Selectivity toward Cyclooxygenase-2

open access: yesIraqi Journal of Pharmaceutical Sciences, 2017
This study includes design and synthesis of new non-steroidal anti-inflammatory agents (NSAIDs) with expected cyclooxygenase-2 (COX-2) selective inhibition to achieve better activity and low gastric side effects.
Nadeem A. Abdul Razzak   +2 more
doaj  

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