Results 151 to 160 of about 96,395 (289)

Peptic ulcer and non-steroidal anti-inflammatory agents [PDF]

Gut, 1987
openaire   +3 more sources

An experimental medicine protocol for exploring the haemodynamic effects of dual agonism at the glucagon‐like peptide‐1 and glucagon receptor in healthy subjects

British Journal of Clinical Pharmacology, EarlyView.
Aims Glucagon‐like peptide‐1 (GLP‐1) and glucagon dual receptor agonists are in clinical development for a range of metabolic conditions, including type 2 diabetes and obesity. The cardiovascular actions at these receptors are well studied, but less is known about their combination.
James Goodman, Victoria E. Parker, Carmel M. McEniery, Giovanni Di Stefano, Annette Hubsch, Evangelia Vamvaka, Jo Helmy, Fotini Kaloyirou, Navazh Jalaludeen, Peter Barker, Lutz Jermutus, Joseph Cheriyan, Philip Ambery, Ian B. Wilkinson   +13 more
wiley   +1 more source

Chemical Composition, Antioxidant, and Antibacterial Activities of Mezilaurus duckei (Lauraceae)

Chemistry &Biodiversity, EarlyView.
ABSTRACT Mezilaurus duckei, a Brazilian endemic tree species found exclusively in the Amazon Rainforest, is primarily exploited for timber in construction. Due to its endangered status, this study aimed to investigate the chemical profile and biological properties of the ethanolic extract and its phases derived from M. duckei leaves. Chemical profiling
Bruna S. Moroto, Valéria S. Gonçalves, David J. Machate, Talita V. Freire, Érica L. Santos, Flávio M. Alves, Ana C. Micheletti, Nídia C. Yoshida   +7 more
wiley   +1 more source

Interleukin (IL)‐5, Eosinophils and IL‐5 Pathway Inhibitors in Eosinophilic Granulomatosis with Polyangiitis.

Arthritis &Rheumatology, Accepted Article.
Alvise Berti, Christian Pagnoux
wiley   +1 more source

Harnessing Nature: Computational and Experimental Insights Into Ipomoea obscura Metabolites for Bladder Cancer Therapy

Chemistry &Biodiversity, EarlyView.
ABSTRACT Ipomoea obscura (L.), a medicinal plant from the Convolvulaceae family, has been traditionally used to treat various ailments. This study evaluated the in vitro cytotoxicity of its ethanolic leaf extract against human bladder cancer T24 cells and investigated its phytochemical constituents through computational methods.
Saravana Prabha Poochi, Rajamanikandan Sundarraj, Manikandan Vani Raju, Meenakshi Kaniyur Chandrasekaran, Rathi Muthaiyan Ahalliya, Chella Perumal Palanisamy, Gopalakrishnan Velliyur Kanniappan, Benod Kumar Kondapavuluri, Muthu Thiruvengadam   +8 more
wiley   +1 more source

Oxidative Stress Modulation and Antileishmanial Activity of Salvinia auriculata

Chemistry &Biodiversity, EarlyView.
Ethanolic extract of Salvinia auriculata showed significant antioxidant and antileishmanial activities. Salviniside II, the major metabolite, was isolated, structurally characterized, and evaluated, but exhibited weaker antiparasitic effects when compared to the whole extract.
Augusto César Rodrigues, Emilha Uzum Papaya, Fernanda da Silva, Carla Cardozo Pinto de Arruda, Edson Lucas dos Santos, Kely de Picoli Souza, Carlos Alexandre Carollo   +6 more
wiley   +1 more source

AASLD practice guidance on drug, herbal, and dietary supplement–induced liver injury

, 2022
Hepatology, EarlyView.
Robert J. Fontana, Iris Liou, Adrian Reuben, Ayako Suzuki, M. Isabel Fiel, William Lee, Victor Navarro   +6 more
wiley   +1 more source

NSAID associated bilateral renal infarctions: a case report

International Journal of Nephrology and Renovascular Disease, 2019
Yejoo Jeon,* Jonathan B Lis,* William G ChangYale School of Medicine, Department of Internal Medicine, Yale University, New Haven, CT, USA*These authors contributed equally to this workAbstract: Renal infarctions (RIs) are caused by interruptions in the ...
Jeon Y, Lis JB, Chang WG
doaj  

Carum carvi and Ormenis multicaulis Extracts: Chemical Analysis and In Vivo Experiments to Evaluate the Synergistic Analgesic and Anti‐Inflammatory Effects

Chemistry &Biodiversity, EarlyView.
ABSTRACT The purpose of the present investigation was to determine the effects of combination of Ormenis multicaulis dry flower methanolic extracts and Carum carvi seed methanolic extracts on pain and inflammation, compared to their use separately. High‐performance liquid chromatography (HPLC) analysis of methanolic extracts showed the presence of ...
El Mahdi Wakrim, Karima Raoui, Hamid Kabdy, Jawad Laadraoui, Mehdi Ait Laaradia, Chafik Terrafe, Sami Mnif, Brahim Bouizgarne, Stefania Garzoli, Abderrahman Chait   +9 more
wiley   +1 more source

Novel Insights Into the Bioactive Profile and Therapeutic Potentials of Indonesian Annona muricata Leaves

Chemistry &Biodiversity, EarlyView.
Pharmacological investigation of the aqueous extract of Annona muricata L. leaves from Indonesia. ABSTRACT This study investigates, for the first time, the comprehensive pharmacological profile of the aqueous extract of Annona muricata L. (graviola) leaves from Indonesia, focusing on its antioxidant, antinociceptive, and anti‐inflammatory properties ...
Sara Oufquir, Fatimazahra Agouram, Hamid Kabdy, Mehdi Ait Laaradia, Khadija Oubella, Baslam Abdelmoniim, Aboufatima Rachida, Stefania Garzoli, Abderrahman Chait   +8 more
wiley   +1 more source