Results 201 to 210 of about 21,849 (255)

Pharmacokinetics of Non‐Steroidal Anti‐Inflammatory Agents

Australian and New Zealand Journal of Medicine, 1978
Summary: Pharmacokinetics of non‐steroidal anti‐inflammatory agents. G. D. Champion and G. G. Graham, Aust. N.Z. J. Med., 1978, 8, Suppl. 1, pp 94–100. The non‐steroidal anti‐inflammatory drugs (NSAID) are well absorbed from the gastrointestinal tract. The only known exception is aspirin.
G D, Champion, G G, Graham
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The regulatory control of non-steroidal anti-inflammatory agents

European Journal of Clinical Pharmacology, 1981
The number of marketed non-steroidal anti-inflammatory agents varies widely from one European country to another, partly as a consequence of differing regulatory policies. During a four-year period, nine of 18 applications to market such drugs in the Netherlands failed; the remaining nine compounds were all licenced; in all, 22 single drug entities of ...
M N, Dukes, I, Lunde
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The chemistry of non-steroidal anti-inflammatory agents

Pure and Applied Chemistry, 1969
Abstract
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Non Steroidal Anti-Inflammatory and Anti-Allergy Agents

Current Medicinal Chemistry, 2002
Non steroidal anti-inflammatory drugs (NSAIDs) are among the most commonly used for inflammation therapy. The major drawback in using the NSAIDs is in their tendency to cause gastrointestinal toxicity. Since the roles of arachidonic acid (A.A) metabolites, as leukotrienes (Lts), prostaglandins (PGs) and thromboxanes (TXA(2)) as mediators of the ...
C A, Kontogiorgis, D J, Hadjipavlou-Litina   +1 more
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Comparative toxicity of non-steroidal anti-inflammatory agents

Pharmacology & Therapeutics, 1994
Comparative toxicity of non-steroidal anti-inflammatory drugs was assessed using the Stanford Toxicity Index consisting of weighted symptoms, laboratory abnormalities and hospitalizations in 2976 consecutively enrolled rheumatoid arthritis patients from eight data bank centers with 27,936 patient-years of observation.
G, Singh, D R, Ramey, D, Morfeld, J F, Fries   +3 more
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Pain control: Non-steroidal anti-inflammatory agents

Seminars in Fetal and Neonatal Medicine, 2006
The non-steroidal anti-inflammatory drugs (NSAIDs) and acetaminophen (paracetamol) are the most common analgesic drugs used in neonates and infants despite limited pharmacodynamic data. Both drugs act through inhibition of cyclooxygenase enzymes. Neonatal acetaminophen clearance is reduced in premature neonates (0.7 L h(-1) x 70 kg(-1)) and increases ...
Evelyne, Jacqz-Aigrain, Brian J, Anderson   +1 more
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Steroid and non-steroid anti-inflammatory agents in asthma.

The European respiratory journal. Supplement, 1989
Anti-inflammatory steroids are the principal agents for the treatment of asthma. Systemic corticosteroids are recommended for the treatment of acute episodes of asthma, whereas inhaled steroids should be used in the long-term prophylaxis of asthma.
MAPP, Cristina, BOSCHETTO, Piera, PICOTTI G, DE MARZO N, FABBRI LM   +4 more
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The selection of non-steroidal anti-inflammatory agents for dermal delivery

International Journal of Pharmaceutics, 2000
An analysis has been conducted to show how the penetration of a selection of non-steroidal anti-inflammatory agents (NSAIDs) through the skin may be predicted. The calculations are based on physicochemical parameters that can be predicted using commercially available software.
J, Hadgraft, J, du Plessis, C, Goosen
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Antimicrobial Activity of Benzydamine, a Non-Steroid Anti-Inflammatory Agent

Journal of Chemotherapy, 1992
The antimicrobial activity of benzydamine (BD), a non-steroid anti-inflammatory agent, was studied using different techniques against 38 strains belonging to 12 microbial species comprising bacteria, yeasts and a fungus. The minimum inhibitory concentrations, minimum lethal concentrations, per cent survivors after 30-minute exposure to BD (0.1 ...
N H, Fanaki, M A, el-Nakeeb
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Non-steroidal Anti-inflammatory Agents and the Skin

1989
The development of topical non-steroidal anti-inflammatory drugs (NSAIDs), devoid of the unwanted effects of corticosteroids but with equal or even greater potency, has been an unattained ideal for many years. Considerable impetus was given to the search by the discovery by Vane (1971) that aspirin and other NSAIDs owed their effectiveness, at least in
M. W. Greaves, S. Shuster
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