Results 231 to 240 of about 144,143 (329)

Lipid metabolism and inflammation as key drivers in preterm birth: A comprehensive analysis

open access: yesInternational Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective To investigate the alterations in lipid metabolites and circulating inflammatory factors associated with preterm birth, elucidate their interactions, and uncover the underlying pathophysiologic mechanisms. By identifying potential predictive biomarkers and informing the development of effective therapeutic interventions, this ...
Shu Xiao, ChaoChao Wei
wiley   +1 more source

Bavachalcone targets transferrin receptor and sensitizes gemcitabine to affect bladder cancer progression

open access: yesiMeta, EarlyView.
Transferrin (Tf) binds extracellular Fe3+ and interacts with transferrin receptor (TFRC) on the cell membrane, leading to endocytosis. Iron is reduced by STEAP3, transported by DMT1 into the cytoplasm, then enters mitochondria to support Fe–S cluster formation, mitochondrial respiration, and ATP production.
Zihao Zhang   +21 more
wiley   +1 more source

A novel clinical interprofessional education experience between pharmacy and dental students in an advanced geriatric surgical dental clinic

open access: yesJACCP: JOURNAL OF THE AMERICAN COLLEGE OF CLINICAL PHARMACY, EarlyView.
Abstract Introduction To address the opioid crisis in the United States, guidelines have prioritized non‐opioid therapies (i.e., non‐steroidal anti‐inflammatory drugs, acetaminophen), for postoperative dental pain. Complex cases may necessitate alternative analgesics, requiring careful pharmacotherapy management.
Justina Lipscomb   +5 more
wiley   +1 more source

A Retrospective Analysis of PK and Response of Oral Ibuprofen in the Treatment of a Patent Ductus Arteriosus in Extremely Low Gestational Age Neonates

open access: yesThe Journal of Clinical Pharmacology, EarlyView.
Abstract Oral ibuprofen is the preferred pharmacotherapeutic option for treatment of a persistent patent ductus arteriosus (PDA), but evidence for its optimal use in extremely low gestational age newborns (ELGANs) remains limited. In the current study, we aimed to investigate the pharmacokinetics and exposure‐response relationship of oral ibuprofen in ...
Mohd Asif   +6 more
wiley   +1 more source

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