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Pharmacokinetics of Non‐Steroidal Anti‐Inflammatory Agents

Australian and New Zealand Journal of Medicine, 1978
Summary: Pharmacokinetics of non‐steroidal anti‐inflammatory agents. G. D. Champion and G. G. Graham, Aust. N.Z. J. Med., 1978, 8, Suppl. 1, pp 94–100. The non‐steroidal anti‐inflammatory drugs (NSAID) are well absorbed from the gastrointestinal tract. The only known exception is aspirin.
Garry G. Graham, G. D. Champion
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The regulatory control of non-steroidal anti-inflammatory agents

European Journal of Clinical Pharmacology, 1981
The number of marketed non-steroidal anti-inflammatory agents varies widely from one European country to another, partly as a consequence of differing regulatory policies. During a four-year period, nine of 18 applications to market such drugs in the Netherlands failed; the remaining nine compounds were all licenced; in all, 22 single drug entities of ...
I. Lunde, M. N. G. Dukes
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Non Steroidal Anti-Inflammatory and Anti-Allergy Agents

Current Medicinal Chemistry, 2002
Non steroidal anti-inflammatory drugs (NSAIDs) are among the most commonly used for inflammation therapy. The major drawback in using the NSAIDs is in their tendency to cause gastrointestinal toxicity. Since the roles of arachidonic acid (A.A) metabolites, as leukotrienes (Lts), prostaglandins (PGs) and thromboxanes (TXA(2)) as mediators of the ...
Christos Kontogiorgis   +1 more
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Comparative toxicity of non-steroidal anti-inflammatory agents

Pharmacology & Therapeutics, 1994
Comparative toxicity of non-steroidal anti-inflammatory drugs was assessed using the Stanford Toxicity Index consisting of weighted symptoms, laboratory abnormalities and hospitalizations in 2976 consecutively enrolled rheumatoid arthritis patients from eight data bank centers with 27,936 patient-years of observation.
Dena R. Ramey   +3 more
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