Results 281 to 290 of about 144,143 (329)
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In vivo suppression of prostaglandin biosynthesis by non-steroidal anti-inflammatory agents
Prostaglandins, 1976In vivo effects of orally administered inhibitors on prostaglandin and F levels were determined in seven organs of the rat. Ibuprofen showed suppression in most tissues three hours after dosing with a return to control values by twenty-four hours. Flurbiprofen and indomethacin showed potent suppression at both three and twenty-four hours after dosing ...
M.A. Wynalda, F.A. Fitzpatrick
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The selection of non-steroidal anti-inflammatory agents for dermal delivery
International Journal of Pharmaceutics, 2000An analysis has been conducted to show how the penetration of a selection of non-steroidal anti-inflammatory agents (NSAIDs) through the skin may be predicted. The calculations are based on physicochemical parameters that can be predicted using commercially available software.
Jeanetta du Plessis +2 more
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Studies on the Mode of Action of Non-Steroidal Anti-Inflammatory Agents [PDF]
, 1972 The recent proposal by Vane and his associates at the Royal College of Surgeons in London (Vane, 1971; Smith and Willis, 1971; Ferreira et al, 1971) that the antiinflammatory activity of indomethacin may be related to its ability to inhibit prostaglandin biosynthesis prompted the present studies.
F. A. KuehlJr. +4 more
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The chemistry of non-steroidal anti-inflammatory agents [PDF]
Pure and Applied Chemistry, 1969 Abstract
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Aminoquinoline Schiff Bases as Non‐Acidic, Non‐Steroidal, Anti‐Inflammatory Agents
, 2017Inflammation is common localized condition which makes body reddened and swollen due to some injury or any infection. The commonly available drugs i. e. diclofenac, ibuprofen etc.
B. Bano +7 more
semanticscholar +1 more source
The regulatory control of non-steroidal anti-inflammatory agents
European Journal of Clinical Pharmacology, 1981The number of marketed non-steroidal anti-inflammatory agents varies widely from one European country to another, partly as a consequence of differing regulatory policies. During a four-year period, nine of 18 applications to market such drugs in the Netherlands failed; the remaining nine compounds were all licenced; in all, 22 single drug entities of ...
I. Lunde, M. N. G. Dukes
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Non Steroidal Anti-Inflammatory and Anti-Allergy Agents
Current Medicinal Chemistry, 2002Non steroidal anti-inflammatory drugs (NSAIDs) are among the most commonly used for inflammation therapy. The major drawback in using the NSAIDs is in their tendency to cause gastrointestinal toxicity. Since the roles of arachidonic acid (A.A) metabolites, as leukotrienes (Lts), prostaglandins (PGs) and thromboxanes (TXA(2)) as mediators of the ...
Christos Kontogiorgis +1 more
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Cochrane Database of Systematic Reviews, 2015
BACKGROUND Acute soft tissue injuries are common and costly. The best drug treatment for such injuries is not certain, although non-steroidal anti-inflammatory drugs (NSAIDs) are often recommended.
Peter G Jones +4 more
semanticscholar +1 more source
BACKGROUND Acute soft tissue injuries are common and costly. The best drug treatment for such injuries is not certain, although non-steroidal anti-inflammatory drugs (NSAIDs) are often recommended.
Peter G Jones +4 more
semanticscholar +1 more source
Current Alzheimer Research, 2005
Inflammation is characteristic of a broad spectrum of neurodegenerative diseases. These include Alzheimer's (AD), Parkinson's (PD), and Huntington's diseases, amyotrophic lateral sclerosis, all of the tauopathies, multiple sclerosis and many other less ...
A. Klegeris, P. Mcgeer
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Inflammation is characteristic of a broad spectrum of neurodegenerative diseases. These include Alzheimer's (AD), Parkinson's (PD), and Huntington's diseases, amyotrophic lateral sclerosis, all of the tauopathies, multiple sclerosis and many other less ...
A. Klegeris, P. Mcgeer
semanticscholar +1 more source
Comparative toxicity of non-steroidal anti-inflammatory agents
Pharmacology & Therapeutics, 1994Comparative toxicity of non-steroidal anti-inflammatory drugs was assessed using the Stanford Toxicity Index consisting of weighted symptoms, laboratory abnormalities and hospitalizations in 2976 consecutively enrolled rheumatoid arthritis patients from eight data bank centers with 27,936 patient-years of observation.
Dena R. Ramey +3 more
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