Results 241 to 250 of about 3,620,680 (377)

KCNJ4 variants disrupt inward‐rectifier potassium channel function and cause refractory epilepsy

open access: yesEpilepsia, EarlyView.
Abstract Objective Epilepsy is a common neurological disorder with a strong genetic basis, most frequently arising from ion channel dysfunction. Although multiple inwardly rectifying potassium (Kir) channels have been implicated in epileptogenesis, the contribution of KCNJ4, which encodes the Kir2.3 channel, has not previously been established in human
Hu Pan   +20 more
wiley   +1 more source

Executive dysfunction and employment in epilepsy

open access: yesEpilepsia, EarlyView.
Abstract Objective Executive dysfunction, affective symptoms, and unemployment are prevalent in patients with epilepsy, yet the relation between these variables remains poorly understood. The present study examined: (1) The relationship between epilepsy‐related variables, affective symptoms, and executive functions (EFs); and (2) how these variables ...
Lisa E. Hauger   +6 more
wiley   +1 more source

Epilepsy syndromes classification

open access: yesEpilepsia Open, EarlyView.
Abstract Epilepsy syndromes are distinct electroclinical entities which have been recently defined by the International League Against Epilepsy Nosology and Definitions Task Force. Each syndrome is associated with “a characteristic cluster of clinical and EEG features, often supported by specific etiologic findings”.
Elaine C. Wirrell   +4 more
wiley   +1 more source

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