Results 61 to 70 of about 3,620,680 (377)

A Depolarizing Leak in Sodium Bicarbonate Cotransporter NBCe1 Causes Brain Edema

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives SLC4A4 encodes electrogenic sodium bicarbonate cotransporter NBCe1, prominently expressed in kidney and brain. Recessive loss‐of‐function variants in SLC4A4 cause proximal renal tubular acidosis, no brain edema. In the brain, NBCe1 is expressed by astrocytes, where it regulates pH and mediates astrocyte volume changes.
Quinty Bisseling   +16 more
wiley   +1 more source

A cross-cultural religiology between reductionism and anti-reductionism

open access: yesHTS Teologiese Studies/Theological Studies, 2023
‘Religion’ has been subjected to two kinds of reduction: one from the various branches of religious studies, the other being the mutual ‘reduction’ among religions.
Guicai Wang
doaj   +1 more source

Professional Philosophy, “Diversity,” and Racist Exclusion: On Van Norden’s Taking Back Philosophy: A Multicultural Manifesto [PDF]

open access: yes, 2018
A critical review essay, this work explains the methodological, material, and ideological reasons for why "diversity" initiatives in philosophy face an up-hill ...
Silva, Grant Joseph
core   +1 more source

[18F]Fluorodeprenyl‐D2 PET as a Tool to Monitor Disease Activity in GAD65‐Ab Autoimmune Encephalitis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To evaluate [18F]fluorodeprenyl‐D2 ([18F]F‐DED) positron‐emission tomography (PET) imaging as a biomarker of disease activity in autoimmune encephalitis (AIE) associated with glutamic acid decarboxylase 65 (GAD65) antibodies. Methods [18F]F‐DED PET was performed in 25 GAD65‐AIE patients and 8 controls using dynamic (0–60 min) and ...
Julia S. Dorneich   +19 more
wiley   +1 more source

Malvina Reynolds Sings the Truth:

open access: yesSanglap: Journal of Literary and Cultural Inquiry, 2022
This article showcases a psychoanalytic context for the idea of historical truth as presented in Malvina Reynolds’s album, Malvina Reynolds Sings the Truth (1967).
Nathan Fleshner
doaj   +1 more source

Post-Truth as a Feature of Hypermodern Times [PDF]

open access: yes, 2018
In this paper I will defend the idea of the success of post-truth as one of the main features of hypermodernity. In order to understand such a claim, I will start by defining “post-truth” and showing the key differences that separate ...
Quintana Paz, Miguel Angel
core  

GAD65 Antibody ELISA With Extended Reportable Range: Validation and Guidance for Neurological Practice

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To (1) validate GAD65‐ELISA detection and quantification for type 1 diabetes mellitus and autoimmune neurological diagnoses, (2) correlate ELISA results (reference range < 5 IU/mL) with established radioimmunoprecipitation assay (RIA; ≤ 0.02 nmol/L), and (3) define ELISA clinical utility and pitfalls.
Andrew McKeon   +11 more
wiley   +1 more source

Academic citizenship in an age of anti-intellectualism

open access: yesJPHE
This essay focuses on the fundamental idea that established theory can guide faculty professional service to inform and educate the general public. More specifically, we explore how faculty can use Boyer's scholarship of engagement as a framework for ...
Jim Vander Putten, Amanda L. Nolen
doaj   +1 more source

MYCOPHENOLATE MOFETIL TREATMENT REDUCES THE RISK OF TREATMENT ESCALATION DUE TO VASCULAR COMPLICATIONS IN LIMITED CUTANEOUS SYSTEMIC SCLEROSIS: EMULATION OF A TARGET TRIAL FROM ITALIAN RHEUMATOLOGY SOCIETY SPRING REGISTRY

open access: yesArthritis Care &Research, Accepted Article.
Objective Mycophenolate Mofetil (MMF) use in limited cutaneous systemic sclerosis (lcSSc) is relatively uncommon due to the lower fibrotic burden and the predominance of the vascular complications. In vitro observations and clinical data from transplanted patients suggest a protective effect of MMF on endothelial function.
Enrico De Lorenzis   +77 more
wiley   +1 more source

Student as Value Based Product: Reconceptualizing the Subjective Nature of Education [PDF]

open access: yes, 2015
In this paper we consider how students are positioned in school classrooms and the effect positioning has on their ontological and social development.
Magill, Kevin R., Rodriguez, Arturo
core   +1 more source

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