Results 101 to 110 of about 1,441,538 (293)

Amuc_1473 Links Gut Microbes to Skeletal Homeostasis and Counteracts Multifactorial Osteoporosis

open access: yesAdvanced Science, EarlyView.
Amuc_1473, a previously uncharacterized protein enriched in Akkermansia muciniphila‐derived extracellular vesicles, is identified as a gut–bone messenger that promotes osteogenesis and inhibits osteoclastogenesis by engaging transcriptional and translational regulators in bone cells.
Shan‐Shan Rao   +28 more
wiley   +1 more source

The Influence of Distributed Power Substation on Automatic Bus Transfer

open access: yesChemical Engineering Transactions, 2017
: In order to make the backup power supply device can work properly, we study the influence of distributed power substation on automatic bus transfer.
Yu Han   +3 more
doaj   +1 more source

MEOX1 Coordinates Autocrine‐Paracrine Programs via SPHK1/S1P to Promote Lymph Node Metastasis in Ovarian Cancer

open access: yesAdvanced Science, EarlyView.
In ovarian cancer, MEOX1 activates the SPHK1/S1P pathway to promote both tumor progression and tumor–stroma crosstalk. MEOX1‐dependent signaling drives CAF activation, enhances VEGF‐C expression, and stimulates lymphangiogenesis, ultimately facilitating lymph node metastasis.
Jiajia Li   +10 more
wiley   +1 more source

A novel hybrid methodology to secure GOOSE messages against cyberattacks in smart grids. [PDF]

open access: yesSci Rep, 2023
Hussain S   +7 more
europepmc   +1 more source

Epigenetic Silencing of RFX7 Defines a Transcriptional Axis Linking Lactate Metabolism to Immune Checkpoint Therapy in Glioblastoma

open access: yesAdvanced Science, EarlyView.
Glioblastoma (GBM) exhibits RFX7 silencing via promoter hypermethylation, which downregulates PIK3IP1 to activate PI3K/AKT signaling, increase lactate accumulation, and enhance histone H4K12 lactylation. This lactylation upregulates PD‐L1/CSF1 expression and drives the immunosuppressive microenvironment formation.
Liying Han   +20 more
wiley   +1 more source

ANALYSIS OF THE 0,4 kV SMART GRID ISLANDING PREVENTION METHOD

open access: yesИзвестия высших учебных заведений и энергетических объединенний СНГ: Энергетика, 2015
The article analyzes the methods affecting autonomous operation regimes of the powergrid sections with distributed electric-power sources (distributed generation) whose connection to the electric-power grid is realized by means of special distributed ...
V. F. Sivokobylenko   +3 more
doaj  

Secreted Nonstructural Protein 3 is a Pathogenic Determinant of Orbivirus

open access: yesAdvanced Science, EarlyView.
This study uncovers a conserved PIP2‐dependent secretory pathway of orbivirus NS3 that induces vascular leakage. Pharmacological disruption of PIP2‐NS3 interaction significantly reduces viral pathogenicity and provides protective efficacy in murine models, establishing PIP2‐mediated NS3 secretion as both a key virulence determinant and a promising ...
Junyong Guan   +11 more
wiley   +1 more source

Injectable Hydrogel with Rapid Coagulation, Low Swelling, and High Burst Pressure Tolerance Properties for Long‐Term Management of Bleeding Wound

open access: yesAdvanced Science, EarlyView.
An injectable PACmC hydrogel with “rigid island‐flexible chain” architecture is developed, featuring low swelling (49.2% within 7 d), strong wet adhesion (46.5 kPa), and high burst pressure (701 mm Hg), which can achieve rapid hemostasis and long‐term sealing in rabbit and porcine models of hepatic and splenic hemorrhage.
Yang Ouyang   +12 more
wiley   +1 more source

Analysis of active anti-islanding methods for photovoltaic systems

open access: yes, 2022
A ampliação dos sistemas de geração distribuída no país traz alguns problemas que devem ser sanados e dentre eles, um de suma importância é o ilhamento. Por motivo de segurança, os sistemas de geração distribuída devem detectar o ilhamento e interromper ...
Hyakutake, Leonardo Ryudi
core  

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