Results 111 to 120 of about 2,823 (249)

Increased expression of aromatase after focal cerebral ischemia: Relevance to neuroprotection and functional recovery

open access: yesNeuroprotection, EarlyView.
Abstract Aim Aromatase is the key enzyme in the biosynthesis of 17β‐estradiol, the most potent estrogen, which has pleiotropic neuroprotective properties. Aromatase levels increase in the brain after stroke, and its gene variants increase susceptibility to stroke. This study aims to determine whether aromatase overexpression improves stroke outcome and
Lindsay Gallagher   +8 more
wiley   +1 more source

Post‐recanalization administration of rapamycin improves functional outcome and reduces infarct size in a rat model of ischemic stroke

open access: yesNeuroprotection, EarlyView.
Experimental design and main findings of the study. Transient middle cerebral artery occlusion was induced for 90 min in rats, followed by intravenous administration of rapamycin or vehicle at the time of recanalization. Functional outcome (Garcia scale and adhesive removal test), magnetic resonance imaging‐based infarct volume assessment, and cerebral
Anna M. Schneider   +4 more
wiley   +1 more source

Best Practices for Scientific Collaboration and Ethical Considerations When Working With Human Remains in Southeast Asia

open access: yesInternational Journal of Osteoarchaeology, EarlyView.
ABSTRACT The roles and responsibilities we occupy as scientists working directly with human remains are diverse, requiring careful ethical consideration. In Southeast Asian contexts, it has been important for us experts and scholars to be in constant correspondence and collaboration, deriving scientific insights into human health, life histories, and ...
Michael Rivera   +19 more
wiley   +1 more source

Navigating the Rapids: How Non‐Governmental Organization Managers Develop Strategic Adaptation to Repressive Political Environments

open access: yesPublic Administration and Development, EarlyView.
ABSTRACT This article explores the management adaptation strategies non‐governmental organizations (NGOs) managers employ in order to operate in repressive political environments. It answers the question: how do NGO managers initiate, manage and sustain internal change when the political/regulatory environment changes?
Charles Kaye‐Essien   +2 more
wiley   +1 more source

How can children and young people have a voice in urban treescapes?

open access: yesPeople and Nature, EarlyView.
Abstract Scientific understanding of climate change has, to date, failed to result in sufficient action. This paper proposes that a deficit model of top‐down learning and dissemination in relation to public engagement with science may be part of the problem, particularly when considering the attitudes, values and empowerment of children and young ...
Simon Carr   +10 more
wiley   +1 more source

Fusion Bonding Repair of Impact‐Damaged Elium Laminates: Comparison of Hot Pressing and Joule Heating

open access: yesPolymer Composites, EarlyView.
Joule Heating‐Enabled Repair of Impact‐Damaged GFRP/Elium Laminates. ABSTRACT This study investigates the repairability of glass fiber‐reinforced Elium (GFRP/Elium) laminates incorporating nickel‐coated carbon veils, focusing on hot pressing and Joule heating as fusion bonding repair techniques.
Ozan Can Zehni
wiley   +1 more source

Sickle Cell Disease: Historical Overview and Current Therapies

open access: yesPrenatal Diagnosis, EarlyView.
ABSTRACT Sickle cell disease (SCD) affects millions worldwide, yet the limited treatment options currently available do not always adequately control the disease and carry significant side effects. At present, the only curative treatment is hematopoietic stem cell (HSC) transplantation, a procedure that carries considerable challenges and numerous ...
Oluwaseun O. Babatunde   +4 more
wiley   +1 more source

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