Results 171 to 180 of about 7,164 (275)

Small molecules as arthropod kinin receptor antagonists, feeding modulators, or novel mosquitocidal agents

open access: yesPest Management Science, EarlyView.
A two‐pronged screen of small molecules – (1) on recombinant kinin receptor and (2) through topical application – identifies kinin receptor antagonists, feeding behavior modulators, and new mosquitocidal molecules. Abstract BACKGROUND Aedes aegypti and Culex quinquefasciatus mosquitoes are primary vectors for numerous human and animal pathogens and ...
Bianca M. Henriques‐Santos   +1 more
wiley   +1 more source

Harnessing Natural Compounds in Psoriasis: Targeting Cellular Pathways for Effective Therapy

open access: yesPhytotherapy Research, EarlyView.
Natural compounds act on key cellular pathways in psoriasis by suppressing keratinocyte hyperproliferation, modulating Th17/IL‐17‐mediated immune responses, and reducing oxidative stress. These multi‐target effects highlight their potential as safer adjunctive therapies alongside conventional treatments.
Hye Jin Lee   +9 more
wiley   +1 more source

Impact of parameterization in multiple acoustic index comparisons: practical cases in terrestrial and underwater soundscapes

open access: yesRemote Sensing in Ecology and Conservation, EarlyView.
Parameter choices in acoustic analyses (sampling frequency, FFT size and window overlap) strongly influence multivariate soundscape separation. Using terrestrial and coral reef recordings, we show that these settings can exaggerate or mask ecological differences, emphasizing the need for parameter sensitivity testing and transparent reporting in ...
Juan C. Azofeifa‐Solano   +8 more
wiley   +1 more source

Science Educators and Researchers Must Uphold the Human Rights of Trans, Nonbinary, and Intersex Persons

open access: yesScience Education, EarlyView.
Abstract Trans, nonbinary, and intersex persons are—and have always been—an integral part of humankind. However, these communities are under attack. We live in a time of growing state repression and the normalization of political violence against trans, nonbinary, and intersex persons throughout much of the world, and we have a responsibility to ...
Quentin C. Sedlacek   +30 more
wiley   +1 more source

Resource reallocation across successive systemic innovations: How Rolls‐Royce shaped the evolution of the turbojet, turboprop, and turbofan

open access: yesStrategic Management Journal, EarlyView.
Abstract Research Summary Despite the importance of resource reallocation in shaping a variety of strategic outcomes, strategy scholars have paid only limited attention to the processes by which firms reallocate their resources across successive systemic innovations.
Gino Cattani   +2 more
wiley   +1 more source

Photodegradable Hydrogels for On‐Demand Modeling of Age‐Related Spatiotemporal ECM Deformation

open access: yesSmall, EarlyView.
A light‐tunable PEG hydrogel enables on‐demand, spatiotemporal modeling of drusen‐like ECM bulges in the aging outer retina. By precisely controlling bulge size, the platform reveals how retinal pigment epithelium morphology adapts to topographical changes without disrupting actin cytoskeleton or polarity, effectively mimicking early ageing before ...
Felix Reul   +8 more
wiley   +1 more source

Next‐Generation Aerogel Electrocatalysts for Oxygen Reduction Reaction

open access: yesSmall, EarlyView.
ABSTRACT Aerogel‐based electrocatalysts have become a groundbreaking class of materials for the oxygen reduction reaction (ORR), distinguished by their ultralight nature, pore networks, and outstanding electrical conductivity. Their interconnected three‐dimensional frameworks offer abundant active sites, efficient diffusion channels, and continuous ...
Kayode Adesina Adegoke   +1 more
wiley   +1 more source

Buchanan and the Social Contract: Coordination Failures and the Atrophy of Property Rights

open access: yesSouthern Economic Journal, EarlyView.
ABSTRACT James Buchanan advocated that societies should be based on a social contract. He rejected anarchy, seeing it as a “Hobbesian jungle” that calls for government intervention to maintain social order. He also opposed theories of spontaneous order. These views led to debates about the compatibility of Buchanan's works with classical liberalism and
Stefano Dughera, Alain Marciano
wiley   +1 more source

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