Results 71 to 80 of about 2,440,020 (219)

Machine Learning‐Based Prediction of Sperm Retrieval Outcomes in Patients With Klinefelter Syndrome: A Multicenter Study With External Validation

Andrology, EarlyView.
ABSTRACT Background The Klinefelter syndrome is a common genetic cause of male infertility, and testicular sperm extraction (TESE) enables sperm retrieval in a subset of affected patients. However, predicting TESE success remains challenging due to the heterogeneous clinical and endocrinological presentation of the Klinefelter syndrome.
Murat Gül, Ali Şahin, Cevahir Özer, Mesut Altan, Tansu Güdelci, Kadir Can Sahin, Mehmet Hamza Gültekin, Muhammed Arif İbis, Mesut Berkan Duran, Burak Sivaslıoğlu, Eray Hasırcı, Mert Kılıç, Ali Can Albaz, Gökhan Çeker, Gianmaria Salvio   +14 more
wiley   +1 more source

The Need for a Global Registry for Charting the Natural History of Klinefelter Syndrome

Andrology, EarlyView.
ABSTRACT Background Although Klinefelter Syndrome (KS) represents the most common sex chromosome aneuploidy, several gaps in knowledge persist regarding optimal management of individuals with this condition. Individuals with KS can have a diverse phenotype including endocrine, neurodevelopmental, and cardiovascular manifestations.
Malika Alimussina, Joseph McElvaney, Corinna Grasemann, Jillian Bryce, Lise Aksglaede, Claudia Boettcher, Lexi Breen, Francesco Carlomagno, Sabine Hannema, Andrea M. Isidori, Inas Mazen, Anna Nordenstrom, S. Faisal Ahmed, Angela K. Lucas‐Herald   +13 more
wiley   +1 more source

Comparison between the levels of anti mullerian hormone after treatment with clomid versus letrozole in polycystic women: an experimental study

Journal of the Pakistan Medical Association
Objective: To compare the effect of two ovulation induction drugs on anti-Mullerian hormone level in polycystic women. Method: The experimental cohort study was done at the infertility outpatient clinics of Al-Yarmouk Teaching Hospital, Baghdad, Iraq,
Manal Madany Abdel Qader, Shatha Sami Hussein, Huda Fadhil Jadi   +2 more
doaj   +1 more source

Anti-Müllerian hormone and lifestyle, reproductive, and environmental factors among women in rural South Africa [PDF]

, 2015
BACKGROUND : Few data exist regarding anti-Müllerian hormone, a marker of ovarian reserve, in relation to environmental factors with potential ovarian toxicity.
Longnecker, Matthew P., Bornman, Maria S. (Riana), Travlos, Gregory S., Whitworth, Kristina W., Wilson, Ralph E., Baird, Donna D., Steiner, Anne Z., Bornman, Riana M. S.   +7 more
core   +1 more source

Anti-Müllerian hormone in men with normal and reduced sperm concentration and men with maldescended testes

, 2009
Objective: To evaluate serum anti-Müllerian hormone (AMH) in well-characterized men with normal and reduced sperm concentration and in men with a history of or persistent maldescended testes as a possible clinical marker of male factor infertility and/or
Dykstra, Nina, Themmen, Axel P.N., Visser, Jenny A.; id_orcid, Tüttelmann, Frank, Nieschlag, Eberhard, Simoni, Manuela, Visser, Jenny A.   +6 more
core   +1 more source

Pubertal Dynamics of Sertoli and Leydig Cell Dysfunction in Klinefelter Syndrome

Clinical Endocrinology, EarlyView.
ABSTRACT Context Klinefelter syndrome (KS), defined by a 47, XXY karyotype, is commonly associated with progressive testicular failure. The precise timing of Sertoli and Leydig cell dysfunction during puberty remains unclear. Objective To determine the onset and progression of testicular insufficiency during puberty in KS, and to assess whether ...
Tredez Axelle, Christine Lefevre, Simon Boussion, Cindy Colson, Iva Gueorguieva, Francois Marcelli, Anne Laure Barbotin, Pascal Pigny, Hamza Benderradji, Clara Leroy   +9 more
wiley   +1 more source

Elevated anti-Müllerian hormone in a stallion (Equus f. caballus) with teratoma and high inguinal testicle

This report describes a stallion presenting a unilateral high inguinal undescended testicle and a unilateral scrotal testicle teratoma. Blood tests showed increased levels of anti-Müllerian hormone. Following castration, histological examination revealed
Hiltrop, Raphaela, Govaere, Jan, Meesters, Maya, Rizzoto, Guilherme, Dewulf, Manon, Govaere J., Hiltrop R, Meesters M, Rizzoto G, Dewulf M   +9 more
core   +1 more source

Overuse of analgesics can affect the fertility biomarker Anti-Müllerian Hormone in females. A translational study [PDF]

Background: Medication overuse headache is a prevalent secondary headache due to the overuse of analgesics, mainly over-the-counter analgesics. Over-the-counter analgesics have been associated with disrupted male endocrinology, while the effects on ...
Jensen, Lea Bejstrup, Westgate, Connar Stanley James, Kristensen, David Møbjerg, Jensen, Rigmor Højland,, Krais, Annette M., Petersen, Morten Rønn, Jeppesen, Janni Vikkelsø,, Kristensen, Stine Gry, Jensen, Rigmor Højland, Lindh, Christian H., Jensen, Lea Bejstrup,, Lindh, Christian H.,, Petersen, Morten Rønn,, Ziebe, Søren, Rouw, Carolien, Ziebe, Søren,, Kristensen, David Møbjerg,, Carlsen, Louise Ninett,, Carlsen, Louise Ninett, Nielsen, Brian Skriver, Westgate, Connar Stanley James,, Rouw, Carolien,, Jeppesen, Janni Vikkelsø, Nielsen, Brian Skriver,, Krais, Annette M.,, Kristensen, Stine Gry,, Lund University.   +26 more
core   +1 more source

Müllerian Duct Aplasia in a Girl With SMARCB1‐Related Coffin–Siris Syndrome: A Rare Co‐Occurring Anomaly

Clinical Genetics, EarlyView.
Genetic causes of Müllerian aplasia remain largely unknown. We report the first molecularly confirmed case of Coffin–Siris syndrome 3 caused by a de novo SMARCB1 variant presenting with Müllerian aplasia, supporting a potential association between BAF complex dysfunction and abnormal Müllerian duct development. Created in BioRender. Herlin, M. K. (2026)
Anneli C. S. Bolund, Esben Thyssen Vestergaard, Edvard Marinovskij, Dorte Launholt Lildballe, Jenny Blechingberg, Morten Krogh Herlin   +5 more
wiley   +1 more source

Wt1 Is Required for the Regression of Müllerian Ducts in Male Mice by Inducing Wif1 and Osx Expression

Cell Proliferation, EarlyView.
Wt1 expressed in the MD mesenchyme promotes MD regression by inducing Wif1 and Osx transcription. In male mice, mesenchyme‐specific inactivation of Wt1 results in MD retention. ABSTRACT In mammals, Müllerian ducts (MDs) are the precursors of the female reproductive tract which regress in males during embryonic development.
Min Chen, Xin Qi, Shanshan Qin, Jia Kang, Changhuo Cen, Miao Guo, Yang Gao, Mengyue Wang, Jiayi Li, Xiuhong Cui, Yanbo Wang, Lan Zhu, Fei Gao   +12 more
wiley   +1 more source