Results 151 to 160 of about 2,480,847 (257)

The First Case of Digenic MODY Diabetes Involving Compound Heterozygosity of Three Variants in the PDX1 and HNF1B Genes

Molecular Genetics &Genomic Medicine, Volume 14, Issue 10, October 2026.
A history of a woman diagnosed with diabetes at 15 led to the discovery of the first digenic MODY with compound heterozygosity of three variants in the PDX1 and HNF1B genes and family cascade screening. This underscores the importance of next‐generation sequencing in the differential diagnosis of diabetes type and extra‐pancreatic abnormalities ...
Magdalena Płonka‐Stępień, Magdalena Szopa, Magdalena Zawada, Maciej T. Malecki   +3 more
wiley   +1 more source

Testicular Biopsies in Adolescent and Adult Andrological Patients: The EAA Clinical Guidelines

Andrology, Volume 14, Issue 7, Page 1906-1928, October 2026.
ABSTRACT Background Histological evaluation of testicular tissue is central to the assessment of infertile men, particularly those at an increased risk of testicular germ cell tumors (TGCT). Traditionally, testicular biopsies have been used primarily for diagnostic purposes, such as the detection of germ cell neoplasia in situ (GCNIS). With advances in
Lise Aksglaede, George Kanakis, Ewa Rajpert‐De Meyts, Davor Jezek, Ferran Algaba, Gert Dohle, Jolanta Slowikowska‐Hilczer, Sabine Kliesch, Hermann M. Behre, Csilla Krausz, Dimitrios G. Goulis, Niels Jørgensen   +11 more
wiley   +1 more source

Veterinarian attitudes towards immunocontraceptive use in cats

Australian Veterinary Journal, Volume 104, Issue 10, Page 701-709, October 2026.
Background The continuously expanding global cat population poses concerns to public health, native ecosystems and individual animal welfare. These concerns have led to additional management strategies to reduce unowned cat numbers, including the development of feline immunocontraceptives.
E Vartola, S Wills, E Cottingham, CD Marth, N Krekeler   +4 more
wiley   +1 more source

The Spectrum of Congenital Hypogonadotropic Hypogonadism: A 30‐Year Experience at a Tertiary Paediatric Centre

Clinical Endocrinology, Volume 105, Issue 4, Page 464-473, October 2026.
ABSTRACT Congenital hypogonadotropic hypogonadism (CHH) is a rare group of disorders of gonadotropin deficiency, either isolated or as a part of multiple pituitary hormone deficiencies (MPHD). We aimed to describe the spectrum of presentation, diagnosis, and management practices of CHH spanning 30 years at an Australian tertiary paediatric centre. This
Minha Kook, Richard G. McGee, Geoffrey Ambler, Yoon Hi Cho   +3 more
wiley   +1 more source

Investigation of anti-mullerian hormone (AMH) level and ovarian response in infertile women with endometriosis in IVF cycles

International Journal of Reproductive BioMedicine, 2018
Background: Endometriosis, can cause ovarian conflict and reduced ovarian reserve that could lead to lower response to assisted reproductive techniques Objective: Current study was conducted to determine the association between level of anti-mullerian ...
Leili Safdarian, Seyedeh Noushin Ghalandarpoor Attar, Ashraf Aleyasin, Marzieh Aghahosseini, Fateme Sadaf Sarfjoo, Sedigheh Hosseinimousa   +5 more
doaj  

Clinical Decision Support Models to Optimize Controlled Ovarian Hyperstimulation: A Scoping Review

Clinical and Translational Science, Volume 19, Issue 10, October 2026.
ABSTRACT Controlled ovarian hyperstimulation (COH) is a precision medicine challenge, with substantial inter‐individual variability in ovarian response affecting treatment efficacy and safety during in vitro fertilization (IVF). Clinical decision support (CDS) tools incorporating statistical, machine learning, and artificial intelligence approaches ...
Robin Z. Y. Lu, Toni J. F. Michael, Vinayak Smith, Beverley J. Vollenhoven, Sophie L. Stocker   +4 more
wiley   +1 more source

Divergent effects of hyperandrogenemia on the female reproductive neuroendocrine axis under different physiological conditions

Journal of Neuroendocrinology, Volume 38, Issue 10, October 2026.
Abstract The hypothalamic–pituitary–gonadal (HPG) axis coordinates reproductive function and incorporates gonadal sex steroid feedback to regulate gonadotropin secretion in a homeostatic manner. In females, ovarian estrogens and progestins act as the primary negative feedback signals to suppress luteinizing hormone (LH) release, whereas in males ...
Lillian Rose, Alexander S. Kauffman
wiley   +1 more source

Ethanolamine plasmalogens increase luteinising hormone pulsatility and are associated with GPR61 expression in bovine gonadotrophin‐releasing hormone neurons

Journal of Neuroendocrinology, Volume 38, Issue 10, October 2026.
Ethanolamine plasmalogens increased LH pulse frequency. GPR61 was expressed in GnRH neurons and gonadotrophs, suggesting a role in neuroendocrine regulation. Ethanolamine plasmalogens (EPls), but not choline plasmalogens (CPls), may act via GPR61 expressed in GnRH neurons in the preoptic area and in anterior pituitary gonadotrophs.
Hiroya Kadokawa, Tomoaki Kubo, Kana Kobayashi, Denis Karani Wanjiru, Yvan Bienvenu Niyonzima   +4 more
wiley   +1 more source

Genetic landscape of a neonatal hypogonadotropic hypogonadism series: Novel variants and phenotypic spectrum

Journal of Neuroendocrinology, Volume 38, Issue 10, October 2026.
Abstract To describe clinical presentation and genetic findings in a cohort of infants with congenital hypogonadotropic hypogonadism (CHH) diagnosed before 2 years of age. From a large cohort of patients who underwent next‐generation sequencing (NGS) for CHH between 2019 and 2025, we identified all patients tested at ≤2 years of age.
Karine Aouchiche, Laure Van Wormhoudt, Kevin Perge, Joanne Dornberger, Cindy Colson, Marine Delagrange, Clara Leroy, Jennifer Ledmazel, Vanessa Menut, Jessica Benarrous Jaillet, Djamel Bendifallah, Mohamad Hage Chehade, Christelle Dib, Anne Barlier, Thierry Brue, Rachel Reynaud, Alexandru Saveanu   +16 more
wiley   +1 more source

Effect of Anti-Müllerian Hormone on Oocytes In Vitro Maturation in Sheep. [PDF]

Int J Mol Sci
Zhang P, Li Y, Shi X, Guo X, Yao D, Sheng H, Zhang J, Cai Y, Zhang X.   +8 more
europepmc   +1 more source