Results 51 to 60 of about 237,988 (290)

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

(ω,c) $(\omega ,c)$-Pseudo periodic functions, first order Cauchy problem and Lasota–Wazewska model with ergodic and unbounded oscillating production of red cells

Boundary Value Problems, 2019
In this paper we study a new class of functions, which we call (ω,c) $(\omega ,c)$-pseudo periodic functions. This collection includes pseudo periodic, pseudo anti-periodic, pseudo Bloch-periodic, and unbounded functions.
Edgardo Alvarez, Samuel Castillo, Manuel Pinto   +2 more
doaj   +1 more source

Anti-periodic solutions of some nonlinear evolution equations

Manuscripta Mathematica, 1989
The author constructs \(\tau\)-anti-periodic solutions \((u(t+\tau)=-u(t))\) to the systems \(u'+\partial G(u)=f\) and \(u''+B(u')+\partial G(u)=f,\) where f is anti-periodic, \(\partial G\) is the gradient of an even function \(G: {\mathbb{R}}^ N\to {\mathbb{R}}^ N,\) \(B: {\mathbb{R}}^ N\to {\mathbb{R}}^ N\) is monotone, odd and \((Bz,z)\geq \alpha |
openaire   +1 more source

Noise-induced synchronization and anti-resonance in excitable systems; Implications for information processing in Parkinson's Disease and Deep Brain Stimulation

, 2019
We study the statistical physics of a surprising phenomenon arising in large networks of excitable elements in response to noise: while at low noise, solutions remain in the vicinity of the resting state and large-noise solutions show asynchronous ...
Ermentrout, G. Bard, Piette, Charlotte, Touboul, Jonathan D., Venance, Laurent   +3 more
core   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Linear difference equations, frieze patterns, and the combinatorial Gale transform

Forum of Mathematics, Sigma, 2014
We study the space of linear difference equations with periodic coefficients and (anti)periodic solutions. We show that this space is isomorphic to the space of tame frieze patterns and closely related to the moduli space of configurations of points in ...
SOPHIE MORIER-GENOUD, VALENTIN OVSIENKO, RICHARD EVAN SCHWARTZ, SERGE TABACHNIKOV   +3 more
doaj   +1 more source

Anti-periodic solutions of Liénard equations with state dependent impulses

Journal of Differential Equations, 2016
The authors study the existence of anti-periodic solutions of Liénard equations with state dependent impulses. Assuming some a priori bounds, the existence of a unique anti-periodic solution is established. Moreover, they construct a sequence of iterates converging point-wise to the solution and provide a bound for the rate of convergence.
Belley, J-M., Bondo, É.
openaire   +2 more sources

Dynamics of two planets in co-orbital motion

, 2010
We study the stability regions and families of periodic orbits of two planets locked in a co-orbital configuration. We consider different ratios of planetary masses and orbital eccentricities, also we assume that both planets share the same orbital plane.
Beaugé, Brasser, C. A. Giuppone, C. Beaugé, Cincotta, Connors, Ferraz-Mello, Goździewski, Hadjidemetriou, Hénon, Jackson, Kortenkamp, Laskar, Laskar, Lee, Michtchenko, Michtchenko, Michtchenko, Mikkola, Mikkola, Mikkola, Namouni, S. Ferraz-Mello, T. A. Michtchenko, Wiegert   +24 more
core   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

Anti-periodic solutions for high-order cellular neural networks with time-varying delays

Electronic Journal of Differential Equations, 2010
In this article, we study anti-periodic solutions for high-order cellular neural networks with time-varying delays. Sufficient conditions for the existence and exponential stability of anti-periodic solutions are presented.
Zuda Huang, Lequn Peng, Min Xu
doaj