Results 61 to 70 of about 955 (246)
“MY TONGUE – IS OF THE PEOPLE”
Proverbium, 2013 Friedrich Nietzsche repeatedly relies on elements of preformulated folk speech to add a certain metaphorical expressiveness to his thoughts and arguments, no matter whether they appear in aphorisms, fragments, poems, letters, essays or entire books.
Wolfgang Mieder
doaj
Consensus Formation and Change are Enhanced by Neutrality
Advanced Science, EarlyView.Neutral agents are shown to enhance both the formation and overturning of consensus in collective decision‐making. A general mathematical model and experiments with locusts and humans reveal that neutrality enables robust consensus via simple interactions and accelerates consensus change by reducing effective population size.
Andrei Sontag +3 more
wiley +1 more source
Localized NF‐κB Inhibition Reduces Lipid Nanoparticle‐Associated Inflammation
Advanced Science, EarlyView.Lipid nanoparticles (LNPs) activate NF‐κB and provoke inflammation that limits therapeutic delivery. By encapsulating selective NF‐κB inhibitors within LNPs, localized suppression of inflammatory signaling is achieved without compromising mRNA expression.
Carolann L. Espy +16 more
wiley +1 more source
“THESE ARE THE TIMES THAT TRY WOMEN’S SOULS”
Proverbium, 2015 While much is known about the proverbial rhetoric of such well-known American male politicians and social reformers as John Adams, Frederick Douglass, Abraham Lincoln, Franklin D. Roosevelt, Harry S.
Wolfgang Mieder
doaj
Electrical Stimulation Directs Formation of Perfused Vasculature in Engineered Tissues
Advanced Science, EarlyView.Electrical stimulation (ESTIM) enhances vasculature formation in engineered human tissues. In 3D endothelial‐fibroblast constructs, conditioning with ESTIM promotes the formation of dense and highly branched networks that rapidly anastomose with mouse vasculature when implanted in vivo. Vessels formed under ESTIM are importantly functionally perfusable.
Katarzyna A. Grzelak +6 more
wiley +1 more source
“GREGOR HAD YET TO DISCOVER THAT LIFE WAS TRULY STRANGER THAN FICTION”
Proverbium, 2016 Readers and reviewers alike have delighted in Insect Dreams. The Half Life of Gregor Samsa (2002), Marc Estrin’s survey of political and cultural developments in Europe and the United States between 1915 and 1945.
Dennis F. Mahoney, Wolfgang Mieder
doaj
Nanoscale Spatial Organization of ARC High‐ and Low‐Order Assemblies at Excitatory Synapses
Advanced Science, EarlyView.ARC (Activity‐Regulated Cytoskeleton‐Associated protein) mediates synaptic plasticity by forming nanoscale assemblies in neurons. Using super‐resolution microscopy and time‐resolved anisotropy with targeted tagging, the study reveals low‐order ARC assemblies at synapses colocalizing with AMPARs, semi‐circular structures at endocytic zones, and 60–80 nm
Martina Damenti +13 more
wiley +1 more source
Proverbium, 2012 This article is a much longer version of a keynote address that I delivered at the “Colloque International de Parémiologie” on July 2, 2011, at the University of Paris-Diderot, at Paris, France.
Wolfgang Mieder
doaj
Advanced Science, EarlyView.ABSTRACT Platelet transfusions to treat bleeding complications use donor‐derived platelets stored at room‐temperature, that have a shelf‐life of only 5–7 days due to bacterial contamination risks. Cold‐stored and freeze‐dried platelets are being investigated for extending shelf‐life, but these still have the inherent challenge of donor‐dependency.
Ujjal Didar Singh Sekhon +20 more
wiley +1 more source
Friend, Not Foe: Lowered Tissue Reactivity to Long‐Term Polyimide Implants
Advanced Science, EarlyView.The choice of optimal neural probe designs remains a major challenge in the field of neurotechnology. This study investigated the biocompatibility of several probe variations, including material, thickness, width, and implantation strategy. It highlights the clear advantage of soft polyimide probes over stiff silicon probes for better device ...
Corinne Orlemann +11 more
wiley +1 more source