Results 141 to 150 of about 15,139 (253)

Baicalein Sensitizes Radioresistant BT549 and MCF7‐R Breast Cancer Cells by Modulating Rac1 Signaling

open access: yesPhytotherapy Research, EarlyView.
ABSTRACT Radioresistance remains a key barrier in breast cancer (BC) treatment. Baicalein, a flavonoid from Scutellaria baicalensis, has shown potential to enhance radiosensitivity. This study investigates its efficacy and mechanism in radioresistant BC models. Radioresistant BC cell models were established via fractionated irradiation and validated by
Zitong Zhao   +3 more
wiley   +1 more source

The Transformational STEM Consciousness Scale: A QuantCrit Measure of a Liberatory STEM Outcome

open access: yesScience Education, EarlyView.
ABSTRACT Guided by QuantCrit, we introduce and validate the Transformational STEM Consciousness (TSC) scale, which fuses students' motivation to pursue racial and social justice through STEM with a critique of STEM's historic complicity in inequity. Surveying 255 undergraduate and graduate students in 18 justice‐integrated STEM courses across 11 US ...
Juan C. Garibay, Lindsay Wheeler
wiley   +1 more source

How Brazilian Public Universities Are Operationalizing The SDGs: Strategic Plans Analysis

open access: yesSustainable Development, EarlyView.
ABSTRACT Despite the importance of universities for Sustainable Development, only a handful of studies have evaluated the implementation levels of SDGs in HEIs in Latin America. To fill this void, this study examines the strategic plans of 70 Brazilian public universities, which account for 92.8% of Federal Universities.
Carolina Grano   +6 more
wiley   +1 more source

Defining Composition–Cytokine Relationships Enables the Design of Lipid Nanoparticles with Programmed Immunogenicity

open access: yesSmall, EarlyView.
Lipid nanoparticle composition governs distinct cytokine programs through the interplay of ionizable and polyethylene glycol‐conjugated (PEGylated) lipids. In vitro profiling, design of experiments (DoE) modeling, and in vivo validation reveal how formulation can tune reactogenicity‐associated pathways, while transgene expression remains the strongest ...
Adam Alexander Walters   +16 more
wiley   +1 more source

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