Results 221 to 230 of about 2,137 (273)

Bridged h‐BN Nanosheets Coatings: Simultaneous Shielding Atomic‐Oxygen Irradiation and Achieving Superior Friction Performance

Advanced Science, EarlyView.
ABSTRACT To confront extreme space environments, a combination of inorganic and organic coatings can provide a pathway for offering highly durable radiation resistance and anti‐friction simultaneously. Herein, a strong interfacial 3D hydrogen‐bonding network is designed to create robust hexagonal boron nitride (h‐BN) based polymer coatings with ...
Zhuoyi Li, Changning Bai, Xingkai Zhang, Yusheng Liang, Wei Wu, Dingrui Zhou, Tao Du, Chunjin Wang   +7 more
wiley   +1 more source

Inhibiting KRAS with CD47 and immune checkpoint overcomes intrinsic resistance to combined KRAS and immune checkpoint inhibitor therapy. [PDF]

Cell Rep Med
Hirade K, Tanaka N, Kajino T, Adachi Y, Kimura R, Kasuya H, Kisoda S, Tan TK, Hayakawa S, Sato T, Yanase S, Kitaura Y, Yamamoto T, Nishioka Y, Muto O, Muraoka D, Fujishita T, Kasuga N, Watanabe K, Sakata Y, Aoki M, Matsushita H, Sanda T, Iida S, Tsuchiya K, Yamaguchi R, Ebi H.   +26 more
europepmc   +1 more source

Membrane Fusion‐Mediated Cytosolic Delivery of Threose Nucleic Acids via Homotypic Nanoparticles Overcomes Drug Resistance in Triple‐Negative Breast Cancer

Advanced Science, EarlyView.
This study introduces a biomimetic “nanofusion” platform that integrates the biostability of threose nucleic acids (TNA) with homotypic cell‐membrane cloaking to combat drug‐resistant TNBC. By leveraging a non‐canonical membrane‐fusion pathway for direct cytosolic delivery, the platform bypasses endosomal sequestration. To achieve potent AKT2 silencing
Wei Zheng, Tristan Juin Han Chang, Xinchao Li, Zhongqi Zhou, Chung Tin, Kenward Vong, Pierre Karam, Pik Kwan Lo   +7 more
wiley   +1 more source

Profiling IgG and IgA antibody responses during vaccination and infection in a high-risk gonorrhoea population. [PDF]

Nat Commun
Stejskal L, Thistlethwaite A, Ramirez-Bencomo F, Rashmi S, Harrison O, Feavers IM, Maiden MCJ, Jerse A, Barnes G, Chirro O, Chemweno J, Nduati E, Cehovin A, Tang C, Sanders EJ, Derrick JP.   +15 more
europepmc   +1 more source

Self-clustering of three CBX2 molecules drives PRC2 to promote facultative heterochromatinization of Polycomb target genes. [PDF]

Mol Cell
Ingersoll S, Trouth A, Angel JC, Luo X, Espinoza A, Wen J, Zhu C, Tucker J, Astatike K, Phiel CJ, Sabaawy H, Kutateladze TG, Wu TP, Yao T, Lu C, Ramachandran S, Ren X.   +16 more
europepmc   +1 more source

Neuroprotective Effect Against Ischemic Stroke of the Novel Functional Drink Containing Anthocyanin and Dietary Fiber Enriched-Functional Ingredient from the Mixture of Banana and Germinated Jasmine Rice. [PDF]

Life (Basel)
Muhammad M, Wattanathorn J, Thukham-Mee W, Phuthong S, Muchimapura S.   +4 more
europepmc   +1 more source

Tumor-infiltrating bacteria disrupt cancer epithelial cell interactions and induce cell-cycle arrest. [PDF]

Cancer Cell
Galeano Niño JL, Ponath F, Ajisafe VA, Becker CR, Kempchinsky AG, Zepeda-Rivera MA, Gomez JA, Wu H, Terrazas JG, Bouzek H, Cromwell E, Chanana P, Wong M, Damania A, White MG, You YN, Kopetz S, Ajami NJ, Wargo JA, Johnston CD, Bullman S.   +20 more
europepmc   +1 more source

Single-cell imaging analysis, therapeutic modeling and a Phase Ib trial validate BCL-2 as a target across heterogeneous castration-resistant prostate cancer. [PDF]

Signal Transduct Target Ther
Jamroze A, Liu X, Hou S, Jess Li W, Yu H, Tracz A, Jacobi J, Li Q, Nastiuk K, Chen X, Huang J, Lin K, Liu M, Cai C, Lu Y, Puzanov I, Kirk JS, Chatta G, Tang DG.   +18 more
europepmc   +1 more source

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Study on Anti-Slide Pile Spacing in Slope Reinforcement Using Anti-Slide Pile with Geocell and Influencing Factors

2013 Fourth International Conference on Digital Manufacturing & Automation, 2013
Anti-slide pile spacing is a very important parameter in slope reinforcement engineering, it affects investment of the reinforcement engineering and slope safety. In order to determine reasonable pile spacing, this paper establishes the calculation model of slope reinforcement using anti-slide pile with geocell. According to the elastic foundation beam
Yang Xiaohua
exaly   +2 more sources