Results 81 to 90 of about 1,262 (267)
工程科学与技术, 2015 :Based on the research of anti-slide pile in landslide control engineering,a new combined anti-slide pile was put forward,which is composed of three single piles,connecting by pile top beam,and has a higher stiffness and less deformation.In the landslide
任永忠, 朱彦鹏, 李海军
doaj
Advanced Healthcare Materials, EarlyView.A human 3D bone niche integrating osteoblasts and osteoclasts enables co‐culture with prostate cancer cell lines and patient‐derived organoids. The engineered niche (i) models aspects of reciprocal phenotypic regulation between osteoblasts and cancer cells, (ii) captures osteoclast‐enhanced osteomimicry in tumor cells, and (iii) establishes a ...
Andrea Mazzoleni +7 more
wiley +1 more source
, 2022 In order to analyse the dynamic evolution characteristics of soil arching during sliding processes, we conducted a series of model push-pile and direct shear tests.
Wei Zhong, Shuai Zhang, Na He
core +1 more source
Advanced Healthcare Materials, EarlyView.This study investigates the M13 bacteriophage as a biomimetic nanovector capable of crossing in vitro models of the blood–brain barrier. By exploiting peculiar transcellular pathways, M13 avoids lysosomal degradation and preserves its structural integrity and functionality.
Silvia Vercellino +12 more
wiley +1 more source
Matrix Stiffness Directs Stemness Signatures in Breast Cancer
Advanced Healthcare Materials, EarlyView.We built lab‐grown breast cancer models to study how the stiffness of the tumor's surroundings influences cancer behavior. Softer environments encouraged more stem‐like, drug‐resistant cells, while stiffer ones kept cells more differentiated. These findings show that tissue mechanics drive cancer diversity and drug resistance, offering new insights for
Chantal Kopecky +4 more
wiley +1 more source
Advanced Healthcare Materials, EarlyView.Gellan gum fluid gel (FG) enables controlled ocular delivery of mesenchymal stromal cell (MSC)‐derived extracellular vesicles (EV). Its shear‐thinning, solid‐liquid‐solid rheology ensures prolonged ocular retention. Sustained MSC‐EV release (∼18% in 6 hrs) supports effective EV ocular delivery.
Seyedmohammad Moosavizadeh +7 more
wiley +1 more source
Seismic design of multiple anti-slide piles by strength reduction dynamics analysis method
, 2015 Landslide thrust is too large and the bearing capacity of a single anti-slide pile is difficult to meet this requirement, multiple anti-slide piles are chosen to solve this problem. However, due to the complexity of multiple anti-slide piles, the related
Lai, Jie +4 more
core
Frontiers in Earth ScienceAnti-slide piles are widely used for landslide mitigation, providing an effective engineering solution for slope protection. A critical factor in the design and performance of these structures is the soil arching effect, which arises from the interaction
Chunmei Zhou +3 more
doaj +1 more source
Advanced Healthcare Materials, EarlyView.Nanoemulsion delivery of a TLR7 agonist enhances safety and promotes colocalization with Leishmania‐infected macrophages in skin lesions, enabling a ∼2‐log reduction in parasite burden. However, tissue‐level constraints and TLR‐driven regulatory feedback generate a mixed immune response that limits complete parasite clearance.
Carmen Palomino‐Cano +11 more
wiley +1 more source
Stress mechanism of anti-slide pile landslide in earthquake
Journal of the Croatian Association of Civil EngineersBased on the geomechanical analysis of typical examples of slope reinforcement and indoor model test analysis, this study analyses the influence of earthquakes on the dynamic response of anti-slide piles supporting gravel soil slopes under different embedment depths and soil strengths.
Feng Sun +4 more
openaire +1 more source