Results 61 to 70 of about 8,495 (251)

Cardiotoxicity of BRAF/MEK inhibitors

British Journal of Pharmacology, EarlyView.
Abstract Rapidly accelerated fibrosarcoma type B/B‐Raf proto‐oncogene, serine/threonine kinase (BRAF) and mitogen‐activated protein kinase (MEK) inhibitors have transformed outcomes in cancer therapy, particularly in melanoma. However, cardiovascular toxicities are increasingly recognized in real‐world clinical practice.
Katharina Seuthe, Valerie Lohner, Kevin Terre, Thomas Riffelmacher, Roman Pfister   +4 more
wiley   +1 more source

Efficacy of class III antiarrhythmics and magnesium combination therapy for atrial fibrillation

, 2012
Atrial fibrillation is a common cardiac arrhythmia, and has been a significant financial burden. Class III antiarrhythmics such as dofetilide, ibutilide, and amiodarone are indicated for rhythm control.
Wang,Amy
core   +2 more sources

Arrhythmias associated with immune checkpoint inhibitor therapy—A clinical perspective

British Journal of Pharmacology, EarlyView.
Immune checkpoint inhibitors (ICIs) have transformed cancer therapy but are associated with a growing spectrum of cardiovascular immune‐related adverse events. Among these, arrhythmias represent a rare yet potentially life‐threatening complication. ICI‐induced arrhythmias encompass a wide clinical spectrum, including atrial arrhythmias, conduction ...
Dong Wang, Melanie Ricke‐Hoch, David Duncker, Johann Bauersachs, Dominik Berliner   +4 more
wiley   +1 more source

Comparing the Impact of Different Antiarrhythmic Classes on Clinical Outcomes Following Atrial Fibrillation Catheter Ablation

Pharmaceuticals
Background/Objectives: Catheter ablation has become the standard of care for patients with symptomatic and drug-refractory atrial fibrillation (AF). Both Class IC and Class III antiarrhythmic drugs (AADs) are effective in preventing early recurrences of ...
Andrej Belančić, Yusuf Ziya Sener, Metin Oksul, Cansu Ozturk, Serdar Soner, Adnan Duha Comert, Gamze Yeter Arslan, Dinko Vitezić, Bojan Jelaković, Erkan Baysal   +9 more
doaj   +1 more source

Mental Health Disorders in End‐Stage Kidney Disease: A Narrative Review of Clinical Considerations for Integrated Management

Hemodialysis International, EarlyView.
ABSTRACT Introduction End stage kidney disease (ESKD) is associated with a high prevalence of depression and anxiety, arising from both biological factors and the psychosocial burden of chronic dialysis care. Approximately 25%–30% of dialysis patients experience clinically significant depressive symptoms when assessed by structured clinical interview ...
Kunal Malhotra, Jordan Fangue‐Nelon, Garima Singh   +2 more
wiley   +1 more source

STATE OF THE ART PHARMACOLOGICAL THERAPY FOR ATRIAL FIBRILLATION

Российский кардиологический журнал, 2017
Pharmacological therapy remains the primary approach to atrial fibrillation (AF). Management of all AF patients includes the decision on rate or rhythm control. The latter means antiarrhythmic drugs application that are being selected primarily by safety
S. G. Kanorsky, Yu. S. Kovalenko
doaj   +1 more source

Catheter Ablation: Evolution and Efficiencies

Journal of Cardiovascular Electrophysiology, EarlyView.
ABSTRACT The present review includes a discussion the goals and pitfalls of efficiency in the medical profession, a historical perspective on the evolution of catheter ablation in the field of electrophysiology (EP), and the data regarding the relationship between efficiency and outcomes in the EP lab. Focus on efficacy is critical to maximize resource
Aravind G. Kalluri, Bradley P. Knight
wiley   +1 more source

Theoretical basis and search for new methods of cardiac arrhythmias' pathogenetic therapy

Российский кардиологический журнал, 2005
Efficacy of cardiac arrhythmias (CA) pharmacotherapy does not exceed 70%; incidence of adverse effects, causing treatment discontinuation, is as high as 10-30%. The need for CA pharmacotherapy improvement is obvious.
V. M. Moroz, T. N. Lipnitsky
doaj  

Clinical Utility of Tissue Proximity Indication With a Variable‐Loop Circular Catheter for Pulmonary Vein Isolation

Journal of Cardiovascular Electrophysiology, EarlyView.
ABSTRACT Background The variable‐loop circular catheter (VLCC, VARIPULSE) is a pulsed‐field ablation (PFA) catheter equipped with a Tissue Proximity Indication (TPI) function, which monitors catheter‐tissue contact. Although TPI‐negative sites have been reported to contribute to gap formation, no studies have evaluated the utility of real‐time function.
Masataka Narita, Daisuke Kawano, Naomichi Tanaka, Tsukasa Naganuma, Wataru Sasaki, Kazuhisa Matsumoto, Kei Matsumoto, Hitoshi Mori, Yoshifumi Ikeda, Ritsushi Kato   +9 more
wiley   +1 more source

Time‐Dependent Diagnostic Yield and Therapeutic Impact of Implantable Loop Recorders, Brugada Syndrome as the Exception

Journal of Cardiovascular Electrophysiology, EarlyView.
Diagnostic yield and therapeutic impact varied substantially according to the indication for implantation. Actionable diagnoses were concentrated in the early follow‐up period for syncope and palpitations, whereas late atrial fibrillation detection after cryptogenic stroke could still modify antithrombotic management. In contrast, patients with Brugada
Luigi Cocchiara, Benedetta Brescia, Procolo Marchese, Stefano Nardi, Luigi Argenziano, Gianmarco Arabia, Marco Micillo, Francesca Gennaro, Giovanni Mazzotta, Lucio Addeo, Alessandro Landolfi, Emiliano Calvi, Manuel Cerini, Alessio Nicolai, Teresa Strisciuglio, Pasquale Vergara, Giovanni Esposito, Antonio Rapacciuolo   +17 more
wiley   +1 more source