Results 231 to 240 of about 311,209 (306)

Cinnamic‐Hydroxamic‐Acid Derivatives Exhibit Antibiotic, Anti‐Biofilm, and Supercoiling Relaxation Properties by Targeting Bacterial Nucleoid‐Associated Protein HU

Advanced Science, EarlyView.
Cinnamic‐hydroxamic‐acid derivatives (CHADs) are identified as novel inhibitors of the bacterial nucleoid‐associated protein HU, exhibiting potent antibacterial, anti‐biofilm (both inhibition and eradication), and DNA relaxation (anti‐supercoiling) activities. Moreover, CHADs demonstrate strong synergistic effects with multiple antibiotics.
Huan Chen, Yingqi Xu, Zhaoping Xiong, Hongliang Wang, Xin Wang, Yue Kang, Zhonglin Wang, Xiaoyan Zeng, Yahui Liu, Yehuan Zheng, Wei Chen, Mengzhe Li, Zhenyue Hu, Chi Xu, Yue Wu, Yawen Wang, Zuyi Yuan, Shuai Yuan, Huadong Liu, Steve Matthews, Nan Qiao, Yan Li, Bing Liu   +22 more
wiley   +1 more source

Balanced Expression of the Diiron Oxygenase BioE Is Essential for Biotin Homeostasis in Elizabethkingia meningoseptica

Advanced Science, EarlyView.
BioE is a new diiron oxygenase that catalyzes the conversion of long‐chain acyl groups into pimeloyl thioester, initiating biotin synthesis. The overexpression of EmBioE disrupts lipid metabolic homeostasis, requiring repressor BioL to maintain a balance between long‐chain fatty acids and biotin synthesis.
Meng Zhang, Ying‐ying Fu, Xiaoqiang Yang, Qiuying Qin, Xinyu Su, Jiaming Fang, Yanhua Kang, Qingwen He, Zhi Ruan, Yongchang Xu   +9 more
wiley   +1 more source

Unveiling the antibacterial mechanism of resveratrol against Aeromonas hydrophila through proteomics analysis. [PDF]

Front Cell Infect Microbiol
Fu Y, Zhang L, Lin Y, Zhao X, Chen H, Zhong Y, Jiang W, Wu X, Lin X.   +8 more
europepmc   +1 more source

A Mussel‐Inspired Bioadhesive Patch to Selectively Kill Glioblastoma Cells

Advanced Science, EarlyView.
An innovative mussel‐inspired bioadhesive patch has been developed for post‐surgical glioblastoma treatment. The patch, which adheres strongly in biological environments, releases a localized treatment. This treatment, acting via reactive oxygen species, shows specific toxicity to glioblastoma cells.
Jose Bolaños‐Cardet, Sara Pugliese, Jordi Bruna, Daniel Ruiz‐Molina, Salvio Suárez‐García, Victor J. Yuste   +5 more
wiley   +1 more source

Disruption of Cell Membranes and Redox Homeostasis as an Antibacterial Mechanism of Dielectric Barrier Discharge Plasma against Fusarium oxysporum. [PDF]

Int J Mol Sci
Yu S, Sun J, Chen H, Chen W, Zhong Q, Zhang M, Pei J, He R, Chen W.   +8 more
europepmc   +1 more source

Electrochemiluminescence Drives Photodynamic Therapy In Vivo

Advanced Science, EarlyView.
Electrochemiluminescence (ECL)‐driven photodynamic therapy (PDT) for in vivo cancer treatment is reported for the first time. The flexible ECL patch exhibits stable and intense luminance under alternating current voltage, enabling efficient photosensitization to generate reactive oxygen species that damage cancer cells, thus leading to significant ...
Jia‐Bao Lin, Ling‐Ling Xu, Yong Liu, Hang Gao, Hong‐Yuan Chen, Jing‐Juan Xu   +5 more
wiley   +1 more source

The Combined Antibacterial Mechanism of Ferulic Acid and ε-Polylysine Hydrochloride in <i>Shewanella putrefaciens</i> and the Effect of Their Application on the Storage Quality of Refrigerated Crayfish (<i>Procambarus clarkii</i>) with Plasma-Activated Water. [PDF]

Foods
Cui Y, Zhang T, Zhao D, Gao S, Liu Y, Yang X, Lu H, Gao X.   +7 more
europepmc   +1 more source

Navigating the Ethereal Tightrope: The Nanogenerator Manipulates Neurons for Immune Equilibrium

Advanced Science, EarlyView.
This review explores how nanogenerators modulate neuroimmune responses, offering innovative strategies for treating neurological disorders. By interfacing with neural pathways, they enable precise control of immune activity, especially via vagus nerve stimulation.
Jia Du, Rui Deng, Ya Wu, Hong‐Xia Ren, Zong‐Hong Lin, Yang‐Bao Miao   +5 more
wiley   +1 more source

Antibacterial mechanism of Lactiplantibacillus plantarum SHY96 cell-free supernatant against Listeria monocytogenes revealed by metabolomics and potential application on chicken breast meat preservation. [PDF]

Food Chem X
Liang M, Wang H, Zhou Z, Huang Y, Suo H.
europepmc   +1 more source

Visible Light‐Activated ZnO@CuO Coaxial Nanofibers Enhance Infected Skin Wound Healing Through Construction of p‐n Heterojunctions

Advanced Science, EarlyView.
Coaxial ZnO@CuO nanofibers activated by visible light generate ROS through enhanced photocatalytic reactions driven by improved electron hole separation in the heterojunction. This strategy enables rapid antimicrobial activity and early infection control, thereby promoting the healing of MRSA infected and diabetic wounds with biosafe and easily ...
Pengrui Dang, Han Zhao, Chenguang Zhang, Jiechen Wang, Fangyu Zhu, Qinqiu Zhong, Wenyi Zeng, Xinyuan Wang, Yumin Chen, Xu Yan, Xuliang Deng, Wenwen Liu   +11 more
wiley   +1 more source