Results 21 to 30 of about 262,340 (261)

Role of intestinal mucin-2 in the effectiveness of the treatment of Helicobacter spp. infection in laboratory mice

Вавиловский журнал генетики и селекции, 2015
Abnormal synthesis of the main intestinal proteo­glycan mucin-2 is typical of ulcerative colitis and Crohn’s disease in humans. Those morphological changes of the mucus layer affect the diversity of the intestinal microflora.
E. A. Litvinova, M. D. Belyaev, A. V. Prokhortchouk, V. S. Korostina, E. B. Prokhortchouk, E. N. Kozhevnikova   +5 more
doaj   +1 more source

Evaluation of the antibacterial effect of Epigallocatechin gallate on the major pathogens of canine periodontal disease and therapeutic effects on periodontal disease mice

Frontiers in Microbiology
BackgroundPeriodontal disease (PD) is a prevalent oral affliction in canines, with limited therapeutic options available. The potential transmission of oral bacteria from canines to humans through inter-species contact poses a risk of zoonotic infection.
Peijia Song, Peijia Song, Yibing Hao, Degui Lin, Yipeng Jin, Jiahao Lin, Jiahao Lin   +6 more
doaj   +1 more source

The effectiveness of antibacterial treatment of the root canal in chronic apical periodontitis using an erbium-chromium laser

Эндодонтия Today, 2022
Aim. To evaluate the effectiveness of antibacterial treatment of root canals in chronic apical periodontitis with an erbiumchromium laser.Materials and methods.
M. A. Postnikov, A. Yu. Rozenbaum, S. E. Chigarina, D. N. Kudryashov, M. B. Khaikin, I. V. Khramova, G. N. Belanov   +6 more
doaj   +1 more source

A Contemporary Strategy for the Surgical Treatment of Destructive Forms of Infective Endocarditis

Креативная хирургия и онкология, 2018
Introduction. Despite recent achievements in medicine, many issues in the diagnosis and treatment of infective endocarditis (IE) remain outstanding.
A. P. Medvedev, V. E. Babokin, Yu. A. Sobolev, V. V. Pichugin, V. A. Chiginev, E. N. Zemskova, N. A. Trofimov, N. L. Blagodatkina   +7 more
doaj   +1 more source

Antibacterial Surface Treatment for Orthopaedic Implants [PDF]

International Journal of Molecular Sciences, 2014
It is expected that the projected increased usage of implantable devices in medicine will result in a natural rise in the number of infections related to these cases. Some patients are unable to autonomously prevent formation of biofilm on implant surfaces.
Jiri Gallo, Martin Holinka, Calin Moucha
openaire   +2 more sources

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

L‐aspartate oxidase provides new insights into fumarate reduction in anaerobic darkness in Synechocystis sp. PCC6803

FEBS Letters, EarlyView.
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil, Jeffrey A. Hawkes, Cecilia Blikstad, Pia Lindberg   +3 more
wiley   +1 more source

Differentiated approach to antibiotic therapy in premature rupture of membranes

Медицинский совет, 2015
The article is devoted to the issues of prescribing antibiotic therapy to pregnant women with premature rupture of membranes. The differentiated approach to the choice of drugs is based on identifying infectious agents in the vagina by polymerase chain ...
A. G. Mustafayeva, V. N. Kuzmin
doaj   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Antibacterial gas therapy: Strategies, advances, and prospects

Bioactive Materials, 2023
One of the challenges posed by current antibacterial therapy is that the expanded and massive use of antibiotics endows bacteria with the ability to resist almost all kinds of antibiotics.
Tian-Yu Wang, Xiao-Yu Zhu, Fu-Gen Wu
doaj   +1 more source