Results 21 to 30 of about 38,287 (243)
Synthesis and Evaluation of Saccharide-Based Aliphatic and Aromatic Esters as Antimicrobial and Antibiofilm Agents [PDF]
, 2019 A small library of sugar-based (i.e., glucose, mannose and lactose) monoesters containing hydrophobic aliphatic or aromatic tails were synthesized and tested.
Biondo, Francesca +6 more
core +1 more source
Promising Antibiofilm Activity of Peptidomimetics [PDF]
Frontiers in Microbiology, 2018 Pathogenic biofilms are a global health care concern, as they can cause extensive antibiotic resistance, morbidity, mortality, and thereby substantial economic loss. Scientific efforts have been made over the past few decades, but so far there is no effective treatment targeting the bacteria in biofilms. Antimicrobial peptidomimetics have been proposed
Rafael Gomes Von Borowski +4 more
openaire +3 more sources
Volatiles from Subtropical Convolvulaceae That Interfere with Bacterial Cell-to-Cell Communication as Potential Antipathogenic Drugs [PDF]
, 2016 Increasing chronic bacterial infections create an urgent need for new antimicrobial agents or strategies for their control. Targetingvirulence is one of the alternative approaches to find new medicines to treat persistent infections due to bacteria with ...
Arena, Mario Eduardo +5 more
core +4 more sources
Synthetic antibiofilm peptides
Biochimica et Biophysica Acta (BBA) - Biomembranes, 2016 Bacteria predominantly exist as multicellular aggregates known as biofilms that are associated with at least two thirds of all infections and exhibit increased adaptive resistance to conventional antibiotic therapies. Therefore, biofilms are major contributors to the global health problem of antibiotic resistance, and novel approaches to counter them ...
César, de la Fuente-Núñez +4 more
openaire +2 more sources
Antibiofilm Activity of Plant Polyphenols [PDF]
Molecules, 2016 In the history of human medicine, antibiotics represent epochal examples of medical progress. However, with an approaching antibiotic crisis due to the emergence and extensive spread of antimicrobial resistance among bacterial agents, as well as to increasing number of patients with chronic and recalcitrant bacterial biofilm-associated infections, the ...
Lívia Slobodníková +4 more
openaire +3 more sources
Social interactions in the Burkholderia cepacia complex : biofilms and quorum sensing [PDF]
, 2010 Burkholderia cepacia complex bacteria are opportunistic pathogens that cause respiratory tract infections in susceptible patients, mainly people with cystic fibrosis. There is convincing evidence that B.
Coenye, Tom
core +2 more sources
Antibiofilm Properties of Acetic Acid [PDF]
Advances in Wound Care, 2015 Bacterial biofilms are known to be extremely tolerant toward antibiotics and other antimicrobial agents. These biofilms cause the persistence of chronic infections. Since antibiotics rarely resolve these infections, the only effective treatment of chronic infections is surgical removal of the infected implant, tissue, or organ and thereby the biofilm ...
Bjarnsholt, Thomas +8 more
openaire +3 more sources
Real-Time Assessment of Staphylococcus aureus Biofilm Disruption by Phage-Derived Proteins
Frontiers in Microbiology, 2017 A current focus of research is the development of new tools for removing bacterial biofilms in industrial settings. Bacteriophage-encoded proteins, such as endolysins, virion-associated peptidoglycan hydrolases, and exopolysaccharide depolymerases, have ...
Diana Gutiérrez +5 more
doaj +1 more source
Antibiotics, 2023 Resistant bacteria may kill more people than COVID-19, so the development of new antibacterials is essential, especially against microbial biofilms that are reservoirs of resistant cells.
Sara Scandorieiro +7 more
doaj +1 more source
Structure-activity relationship study of the plant-derived decapeptide OSIP108 inhibiting Candida albicans biofilm formation [PDF]
, 2014 We performed a structure-activity relationship study of the antibiofilm plant-derived decapeptide OSIP108. Introduction of positively charged amino acids R, H, and K resulted in an up-to-5-fold-increased antibiofilm activity against Candida albicans ...
Cammue, Bruno P. A. +6 more
core +1 more source