Results 61 to 70 of about 18,389 (202)

A Blood‐Derived Double‐Network Hydrogel with Robust Wet Adhesion for Keratinized Mucosa Regeneration via Neutrophil Phenotype Reprogramming and Mechanophysical Niche Modulation

Advanced Science, EarlyView.
The iPRF‐MA/Alg‐NHS/Lut@EGCG (PGAE) double‐network hydrogel achieves durable wet adhesion in the oral environment. It simultaneously reprograms neutrophils from NETosis to phagocytosis for biofilm clearance, and activates the FAK‐RhoA‐YAP mechanotransduction pathway in gingival fibroblasts to drive extracellular matrix remodeling, thereby promoting ...
Sicong Ren, Xinting Yang, Jingxia Chen, Yihan Wang, Jian Feng, Jing Zhou, Jiaxin Luo, Jingjie Zhai, Quan Lin, Yanmin Zhou   +9 more
wiley   +1 more source

Mesoporous Catalytic‐Adsorptive Nanoregulator Orchestrates Biofilm eDNA/LPS Disassembly and TLR9/TLR4 Immune Reprogramming to Resolve Diabetic Foot Infections

Advanced Science, EarlyView.
Chronic diabetic wounds are hindered by a “dual trap” of biofilm resistance and hyperinflammation. A mesoporous catalytic‐adsorptive nano‐regulator is developed to dismantle this barrier through simultaneous eDNA degradation and LPS sequestration. By silencing TLR4/9‐mediated signaling, the platform clears resilient pathogens and reprograms the immune ...
Junfeng Song, Yang Song, Xirui Huang, Xingjin Li, Lifei Gao, Yixiang Wang, Tianbao Zhu, Xiaomin Li, Shuai Wang, Tiancong Zhao, Dongyuan Zhao   +10 more
wiley   +1 more source

Interspecies Biofilm Dynamics Among Staphylococci: Inflammatory Contributions to Chronic Rhinosinusitis

International Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Introduction Staphylococcus species are frequently isolated from the sinonasal niche of chronic rhinosinusitis (CRS) patients. While Staphylococcus aureus is often associated with recalcitrant CRS, Staphylococcus epidermidis and Staphylococcus lugdunensis are largely deemed commensal.
Sintayehu Ambachew, Mahnaz Ramezanpour, Clare M. Cooksley, Sholeh Feizi, Muhammed Awad, Kevin Aaron Fenix, Peter‐John Wormald, Alkis J. Psaltis, Sarah Vreugde   +8 more
wiley   +1 more source

MINYAK MASOYI SEBAGAI ANTIBIOFILM

, 2021
Penyakit infeksi masih merupakan penyebab utama morbiditas dan mortalitas di dunia. Disamping itu penyakit infeksi bertanggung jawab pada penurunan kualitas hidup jutaan penduduk di berbagai negara maju dan berkembang. Menurut WHO, sepertiga dari 25 juta kematian di seluruh dunia pada tahun 2011, disebabkan oleh penyakit infeksi.
openaire   +2 more sources

ANTIBIOFILM ACTIVITY OF FIVE NATIVE PLANTS OF KALIMANTAN ISLAND AGAINST Staphylococcus aureus

Jurnal Farmasi Sains dan Praktis
Infections caused by Staphylococcus aureus are an increasing concern in the healthcare sector, particularly due to the rise of antibiotic-resistant strains.
Joko Priyanto Wibowo, Abdul Rahman Wahid, Dewi Setya Paramitha, Restu Dara Wewengkang, Medina Nurrahmah   +4 more
doaj   +1 more source

Promising biotechnological applications of antibiofilm exopolysaccharides

Microbial Biotechnology, 2012
Polysaccharides are polymers of carbohydrates with anenormous structural diversity, from long linear repetition ofthe same monomer to highly branched structures of dif-ferent sugars. This high structural diversity reflects thefunctional diversity of these molecules.
Bernal, P, Llamas, MA
openaire   +3 more sources

Advanced nanotherapeutics for combating ocular infections: Rational design, antimicrobial mechanisms, and therapeutic breakthroughs

BMEMat, EarlyView.
Nanomaterials revolutionize ocular infection treatment by enabling targeted drug delivery and enhanced antimicrobial efficacy against resistant pathogens. This review systematically explores their rational design, multimodal mechanisms, and translational potential for next‐generation anti‐infective therapies.
Yujia Liu, Xuetian Wen, Yue Tan, Rui Zeng, Yijuan Zhang, Tong Lin, Lan Gong, Zichao Luo   +7 more
wiley   +1 more source

Control of biofilm from single and multispecies bacteria associated with food spoilage using metabolite of Streptomyces sp. KP110 and Pseudomonas fluorescens JB 3B

Scientific Reports
Food spoilage bacteria are responsible for food spoilage and often fabricate biofilms on various surfaces. Naturally, biofilms are constructed by multiple bacterial species. These biofilms are more difficult to control compared to single species biofilms.
Budhiarto Halim, Diana Elizabeth Waturangi, Adi Yulandi   +2 more
doaj   +1 more source

A narrow bandgap Schottky heterojunction Fe2N/CeO2 microneedle triggering sonodynamic reactive oxygen species storm for drug‐resistance‐free skin fungal infection

BMEMat, EarlyView.
Inorganic sonosensitizers suffer from inefficient electron‐hole separation, rapid recombination, and wide bandgaps in anti‐fungal applications. We propose MN@Fe2N/CeO2 to directly eliminate fungi without drug resistance. Combining semiconductor CeO2's advantages with Fe2N's high work function and activity enables efficient Schottky heterojunctions ...
Li Wang, Jiayi Yang, Ning Tang, Youbin Zheng, Yichao Hou, Chutong Liu, Lihao Guo, Yingying Liao, Gandong Zhou, Weiwei Wu, Xin Du, Shuxiang Xu, Jie Yin, Miaomiao Yuan   +13 more
wiley   +1 more source

AKTIVITAS ANTIBAKTERI DAN ANTIBIOFILM DARI EKSTRAK DAUN BANGUN-BANGUN (Coleus amboinicus L.) TERHADAP BAKTERI Staphylococcus aureus

JIIS: Jurnal Ilmiah Ibnu Sina
Pembentukan biofilm oleh bakteri khususnya genus Staphylococcus menjadi permasalahan kesehatan yang cukup serius. Berbagai tanaman obat telah digunakan untuk mengendalikan infeksinya, namun belum ada penelitian terkait aktivitas antibiofilm dari Coleus ...
Fitra Romadhonsyah, Aisha Nanda Caela Amry, Annisa Fitria, Arde Toga Nugraha, Arba Pramundita Ramadani, Nangim Khasanah   +5 more
doaj   +1 more source