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Antibiotic Susceptibility Testing with Raman Biosensing [PDF]

Antibiotics, 2022
Antibiotics guard us against bacterial infections and are among the most commonly used medicines. The immediate consequence of their large-scale production and prescription is the development of antibiotic resistance.
Andrei Novikov, Adeliya Sayfutdinova, Ekaterina Botchkova, Dmitry Kopitsyn, Rawil Fakhrullin   +4 more
doaj   +5 more sources

Pooled Antibiotic Susceptibility Testing for Polymicrobial UTI Performs Within CLSI Validation Standards [PDF]

Antibiotics
Background/Objectives: Urinary tract infections (UTIs) pose an increasing risk of antimicrobial resistance, and novel diagnostic tests have been developed to address the limitations of standard urine culture in these cases.
Richard A. Festa, Frank R. Cockerill, Rick L. Pesano, Emery Haley, Natalie Luke, Mohit Mathur, Xiaofei Chen, Jim Havrilla, Michael Percaccio, Jesus Magallon, Shane Erickson, Mandana Ghashghaie, Alain Rosas, David Baunoch   +13 more
doaj   +3 more sources

Microfluidics for Antibiotic Susceptibility and Toxicity Testing [PDF]

Bioengineering, 2016
The recent emergence of antimicrobial resistance has become a major concern for worldwide policy makers as very few new antibiotics have been developed in the last twenty-five years.
Jing Dai, Morgan Hamon, Sachin Jambovane
doaj   +4 more sources

Antibiotic susceptibility testing using minimum inhibitory concentration (MIC) assays [PDF]

npj Antimicrobials and Resistance
Antimicrobial resistance is due to genetic changes that allow bacteria to evade antibiotic treatment. Antimicrobial susceptibility testing is critical for the detection of antibiotic-resistant strains, the selection of effective therapeutic strategies ...
Nikol Kadeřábková, Ayesha J. S. Mahmood, Despoina A. I. Mavridou   +2 more
doaj   +3 more sources

Antibiotic Susceptibility and Resistance Testing: An Overview [PDF]

Canadian Journal of Gastroenterology, 2000
The results of in vitro antibiotic susceptibility testing can predict the clinical response to treatment and guide the selection of antibiotics. The minimum inhibitory concentration (MIC) of an organism is the lowest concentration of an antibiotic that ...
Fiona Smaill
doaj   +4 more sources

Microwell-enhanced optical rapid antibiotic susceptibility testing of single bacteria [PDF]

iScience, 2023
Summary: Bacteria that are resistant to antibiotics present an increasing burden on healthcare. To address this emerging crisis, novel rapid antibiotic susceptibility testing (AST) methods are eagerly needed.
Ireneusz Rosłon, Aleksandre Japaridze, Stef Rodenhuis, Lieke Hamoen, Murali Krishna Ghatkesar, Peter Steeneken, Cees Dekker, Farbod Alijani   +7 more
doaj   +3 more sources

Rapid Bacterial Motility Monitoring Using Inexpensive 3D-Printed OpenFlexure Microscopy Allows Microfluidic Antibiotic Susceptibility Testing [PDF]

Micromachines, 2022
Antibiotic susceptibility testing is vital to tackle the emergence and spread of antimicrobial resistance. Inexpensive digital CMOS cameras can be converted into portable digital microscopes using 3D printed x-y-z stages.
Tai The Diep, Sarah Helen Needs, Samuel Bizley, Alexander D. Edwards   +3 more
doaj   +2 more sources

Results of antibiotic susceptibility testing do not influence clinical outcome in children with cystic fibrosis [PDF]

Journal of Cystic Fibrosis, 2012
Introduction: Patients with CF experience pulmonary exacerbations. These are often initially empirically treated with intravenous antibiotics, with antibiotic choice refined after susceptibility testing.
M N Hurley, Jayesh Bhatt, Alan R Smyth
exaly   +2 more sources

Pooled Antibiotic Susceptibility Testing Performs Within CLSI Standards for Validation When Measured Against Broth Microdilution and Disk Diffusion Antibiotic Susceptibility Testing of Cultured Isolates. [PDF]

Antibiotics (Basel)
Background/Objectives: While new methods for measuring antimicrobial susceptibility have been associated with improved patient outcomes, they should also be validated using standard protocols for error rates and other test metrics.
Haley E, Cockerill FR, Pesano RL, Festa RA, Luke N, Mathur M, Chen X, Havrilla J, Baunoch D.   +8 more
europepmc   +2 more sources

Impact of rapid antibiotic susceptibility testing for Gram-negative bacteremia varies by pathogen type and resistance: a secondary analysis of the RAPIDS GN trial [PDF]

Microbiology Spectrum
In this secondary analysis of 386 subjects with Gram-negative bacteremia enrolled in the RAPIDS GN trial, rapid antibiotic susceptibility testing had a greater benefit on the management of bacteremia caused by antibiotic-resistant compared to antibiotic ...
Ritu Banerjee, Abhigya Giri, Lauren Komarow, Maria Souli, Sarah B. Doernberg, Robin Patel   +5 more
doaj   +2 more sources