Results 21 to 30 of about 410 (175)

Long‐term outcomes in heart failure with preserved ejection fraction: Predictors of cardiac and non‐cardiac mortality

ESC Heart Failure, Volume 10, Issue 3, Page 1835-1846, June 2023., 2023
Abstract Aims Heart failure (HF) with preserved ejection fraction (HFpEF) is associated with cardiovascular (CV) and non‐CV events, but long‐term risk is poorly studied. We assessed incidence and predictors of the long‐term CV and non‐CV events. Methods and results Patients presenting with acute HF, EF ≥ 45%, and N‐terminal pro‐brain natriuretic ...
Angiza Shahim, Marion Hourqueig, Lars H. Lund, Gianluigi Savarese, Emmanuel Oger, Ashwin Venkateshvaran, Lina Benson, Jean‐Claude Daubert, Cecilia Linde, Erwan Donal, Camilla Hage   +10 more
wiley   +1 more source

Sex differences in the generalizability of randomized clinical trials in heart failure with reduced ejection fraction

European Journal of Heart Failure, Volume 25, Issue 6, Page 912-921, June 2023., 2023
Sex differences in randomized clinical trial (RCT) recruitment and clinical outcomes at 1 year. Cumulative incidence functions and adjusted standardized mortality ratios (SMRs) for all‐cause and cardiovascular mortality at 1 year stratified by sex. (A) Cumulative incidence for all‐cause mortality between RCT and registry patients.
Megan Schroeder, Yvonne Mei Fong Lim, Gianluigi Savarese, Kiliana Suzart‐Woischnik, Claire Baudier, Tomasz Dyszynski, Ilonca Vaartjes, Marinus J.C. Eijkemans, Alicia Uijl, Ronald Herrera, Eleni Vradi, Jasper J. Brugts, Hans‐Peter Brunner‐La Rocca, Vanessa Blanc‐Guillemaud, Sandra Waechter, Fabrice Couvelard, Benoit Tyl, Samuel Fatoba, Arno W. Hoes, Lars H. Lund, Christoph Gerlinger, Folkert W. Asselbergs, Diederick E. Grobbee, Maureen Cronin, Stefan Koudstaal   +24 more
wiley   +1 more source

Use of guideline‐recommended medical therapy in patients with heart failure and chronic kidney disease: from physician's prescriptions to patient's dispensations, medication adherence and persistence

European Journal of Heart Failure, Volume 24, Issue 11, Page 2185-2195, November 2022., 2022
Patients with heart failure and chronic kidney disease are less likely to receive and persist on guideline‐recommended medical therapies. Aim Half of heart failure (HF) patients have chronic kidney disease (CKD) complicating their pharmacological management.
Roemer J. Janse, Edouard L. Fu, Ulf Dahlström, Lina Benson, Bengt Lindholm, Merel van Diepen, Friedo W. Dekker, Lars H. Lund, Juan‐Jesus Carrero, Gianluigi Savarese   +9 more
wiley   +1 more source

Trajectories in New York Heart Association functional class in heart failure across the ejection fraction spectrum: data from the Swedish Heart Failure Registry

European Journal of Heart Failure, Volume 24, Issue 11, Page 2093-2104, November 2022., 2022
Stable New York Heart Association (NYHA) class over time was much more frequent than an improvement or a worsening. Follow‐up NYHA class assessment, but not change in NYHA class over time, was independently associated with better prognosis. CI, confidence interval; HR, hazard ratio.
Felix Lindberg, Lars H. Lund, Lina Benson, Ulf Dahlström, Patric Karlström, Cecilia Linde, Giuseppe Rosano, Gianluigi Savarese   +7 more
wiley   +1 more source

Biomarker changes as surrogate endpoints in early‐phase trials in heart failure with reduced ejection fraction

ESC Heart Failure, Volume 9, Issue 4, Page 2107-2118, August 2022., 2022
Abstract Aims No biomarker has achieved widespread acceptance as a surrogate endpoint for early‐phase heart failure (HF) trials. We assessed whether changes over time in a panel of plasma biomarkers were associated with subsequent morbidity/mortality in HF with reduced ejection fraction (HFrEF).
Gianluigi Savarese, Alicia Uijl, Wouter Ouwerkerk, Jasper Tromp, Stefan D. Anker, Kenneth Dickstein, Camilla Hage, Carolyn S.P. Lam, Chim C. Lang, Marco Metra, Leong L. Ng, Nicola Orsini, Nilesh J. Samani, Dirk J. van Veldhuisen, John G.F. Cleland, Adriaan A. Voors, Lars H. Lund   +16 more
wiley   +1 more source

Network meta‐analysis of medical therapy efficacy in more than 90,000 patients with heart failure and reduced ejection fraction

Journal of Internal Medicine, Volume 292, Issue 2, Page 333-349, August 2022., 2022
Abstract Background Following the availability of new drugs for chronic heart failure (HF) with reduced ejection fraction (HFrEF), we sought to provide an updated and comparative synthesis of the evidence on HFrEF pharmacotherapy efficacy. Methods We performed a Bayesian network meta‐analysis of phase 2 and 3 randomized controlled trials (RCTs) of ...
Vincenzo De Marzo, Gianluigi Savarese, Lucia Tricarico, Sofia Hassan, Massimo Iacoviello, Italo Porto, Pietro Ameri   +6 more
wiley   +1 more source

Predictors of primary prevention implantable cardioverter‐defibrillator use in heart failure with reduced ejection fraction: impact of the predicted risk of sudden cardiac death and all‐cause mortality

European Journal of Heart Failure, Volume 24, Issue 7, Page 1212-1222, July 2022., 2022
In this study of 13 475 contemporary treated patients with heart failure with reduced ejection fraction (HFrEF) meeting criteria for primary prevention implantable cardioverter‐defibrillator (ICD) use, only 15.5% had an ICD. While a high predicted proportional risk of sudden cardiac death was appropriately linked to ICD use, the lack of specialized ...
Benedikt Schrage, Lars H. Lund, Lina Benson, Ulf Dahlström, Ramin Shadman, Cecilia Linde, Frieder Braunschweig, Wayne C. Levy, Gianluigi Savarese   +8 more
wiley   +1 more source

Complicanze infettive locali precoci e tardive nella chirurgia otologica [PDF]

Acta Otorhinolaryngologica Italica, 2016
La via retroauricolare rappresenta l’approccio di scelta nel trattamento dell’otite media cronica. Nelle procedure “sporche” l’incidenza della complicanza infettiva locale è del 10%. Il presente studio analizza le infezioni del sito chirurgico dopo
P.L. BASTIER, C. LEROYER, A. LASHéRAS, A.-M. ROGUES, V. DARROUZET, V. FRANCO-VIDAL   +5 more
doaj   +1 more source

Nuove linee guida ISPD per il trattamento della peritonite in dialisi peritoneale: cosa c'è di nuovo?

Giornale di Clinica Nefrologia e Dialisi, 2018
La peritonite rappresenta la principale complicanza legata alla dialisi peritoneale. Sin dal 1983, l'International Society of Peirtoneal Dialysis (ISPD) ha elaborato delle linee guida, revisionate e aggiornate più volte sino al 2010, su prevenzione ...
P. Lisi, R. Corciulo, R. Russo
doaj   +1 more source

Antimicrobial susceptibility of Salmonella spp. strains isolated from Layer Hens in Campania Region from 2000 to 2003

Italian Journal of Animal Science, 2010
Scopo del presente lavoro è stato quello di testare la sensibilità antibiotica di 60 ceppi di Salmonella (S. enteritidis, S. typhimurium, S. gallinarum) isolati da galline ovaiole nel periodo compreso tra il 2000 e il 2003. S.
Alessandro Fioretti, Lucia Francesca Menna, Antonio Baiano Baiano, Mariangela Sensale, Mariarosaria Calabria, Claudia Scarpetta, Ludovico Dipineto   +6 more
doaj   +1 more source