Results 361 to 370 of about 2,694,182 (391)

Discovery of a structural class of antibiotics with explainable deep learning

Nature, 2023
Felix Wong, Erica J. Zheng, Jacqueline A. Valeri, Nina M. Donghia, Melis N. Anahtar, Satotaka Omori, Alicia Li, Andres Cubillos-Ruiz, Aarti Krishnan, Wengong Jin, A. Manson, Jens Friedrichs, Ralf Helbig, B. Hajian, Dawid K. Fiejtek, Florence F. Wagner, Holly H. Soutter, A. Earl, Jonathan M. Stokes, L.D. Renner, James J. Collins   +20 more
semanticscholar   +1 more source

Mutation and Evolution of Antibiotic Resistance: Antibiotics as Promoters of Antibiotic Resistance?

Current Drug Targets, 2002
Antibiotic resistance appearance and spread have been classically considered the result of a process of natural selection, directed by the use of antibiotics. Bacteria, that have to face the antibiotic challenge, evolve to acquire resistance and, under this strong selective pressure, only the fittest survive, leading to the spread of resistance ...
Jesus, Blázquez, Antonio, Oliver, José-María, Gómez-Gómez   +2 more
openaire   +2 more sources

Antibiotics and antibiotic resistance in water environments

Current Opinion in Biotechnology, 2008
Antibiotic-resistant organisms enter into water environments from human and animal sources. These bacteria are able to spread their genes into water-indigenous microbes, which also contain resistance genes. On the contrary, many antibiotics from industrial origin circulate in water environments, potentially altering microbial ecosystems.
Fernando, Baquero, José-Luis, Martínez, Rafael, Cantón   +2 more
openaire   +2 more sources

How antibiotics cause antibiotic resistance

Drug Discovery Today, 1999
Antimicrobial agents are approaching the end of their effectiveness. The prevailing drug development strategy is based on a presumption that results in resistance: that disease can be cured by exploitation of the vulnerabilities in microbial reproduction. Although some did predict the evolution of resistance to such drugs, the mechanisms by which genes
openaire   +2 more sources

Discovery, research, and development of new antibiotics: the WHO priority list of antibiotic-resistant bacteria and tuberculosis.

Lancet. Infectious Diseases (Print), 2017
E. Tacconelli, E. Carrara, A. Savoldi, S. Harbarth, M. Mendelson, D. Monnet, C. Pulcini, G. Kahlmeter, J. Kluytmans, Y. Carmeli, M. Ouellette, Kevin Outterson, J. Patel, M. Cavaleri, E. Cox, Chris R Houchens, M. Grayson, P. Hansen, Nalini Singh, U. Theuretzbacher, N. Magrini, A. Aboderin, S. Al-Abri, Nordiah Awang Jalil, N. Benzonana, S. Bhattacharya, A. Brink, F. Burkert, O. Cars, G. Cornaglia, O. Dyar, A. Friedrich, A. Gales, Sumanth Gandra, C. Giske, D. Goff, H. Goossens, T. Gottlieb, M. Guzman Blanco, W. Hryniewicz, D. Kattula, Tim Jinks, S. Kanj, Lawrence Kerr, M. Kieny, Yang Soo Kim, R. Kozlov, J. Labarca, R. Laxminarayan, K. Leder, L. Leibovici, Gabriel Levy-Hara, Jasper Littman, S. Malhotra-Kumar, V. Manchanda, L. Moja, B. Ndoye, Angelo Pan, D. Paterson, M. Paul, Haibo Qiu, P. Ramón-Pardo, J. Rodríguez-Baño, M. Sanguinetti, S. Sengupta, M. Sharland, Massinissa Si-Mehand, L. Silver, W. Song, M. Steinbakk, Jens Thomsen, G. Thwaites, J. V. D. van der Meer, N. van Kinh, S. Vega, M. Villegas, A. Wechsler-Fördös, H. Wertheim, Evelyn Wesangula, N. Woodford, Fidan Yilmaz, Anna Zorzet   +81 more
semanticscholar   +1 more source

Antibiotics

Annual Review of Microbiology, 1955
H, EAGLE, A K, SAZ
openaire   +4 more sources

Antibiotics

Nursing, 2017
Kavitha S, Dalal, Mary Barna, Bridgeman
openaire   +2 more sources

Antibiotics and Antibiotic Prophylaxis

2019
An understanding of the principles of prescribing antibiotics in dentistry is paramount to their successful use in the outpatient setting. While the number of classes of antibiotics and specific agents useful in the management of routine odontogenic infections is relatively small when compared to those used in medicine, the dentist must understand the ...
openaire   +1 more source

Comprehensive evaluation of antibiotics emission and fate in the river basins of China: source analysis, multimedia modeling, and linkage to bacterial resistance.

Environmental Science and Technology, 2015
Qian-Qian Zhang, G. Ying, Chang-Gui Pan, You-Sheng Liu, Jian-Liang Zhao   +4 more
semanticscholar   +1 more source

The role of antibiotics and antibiotic resistance in nature

Environmental Microbiology, 2009
Summary Investigations of antibiotic resistance from an environmental prospective shed new light on a problem that was traditionally confined to a subset of clinically relevant antibiotic‐resistant bacterial pathogens. It is clear that the environmental microbiota, even in apparently antibiotic‐free environments, possess an enormous ...
openaire   +2 more sources