Results 101 to 110 of about 17,492 (243)

Anti-hLAMP2-antibodies and dual positivity for anti-GBM and MPO-ANCA in a patient with relapsing pulmonary-renal syndrome [PDF]

, 2011
Background Pulmonary-renal syndrome associated with anti-glomerular basement membrane (GBM) antibodies, also known as Goodpasture's syndrome, is a rare but acute and life-threatening condition.
Christoph Etter, Ariana Gaspert, Stephan Regenass, Rudolf P Wüthrich, Thomas Kistler, Renate Kain, Clemens D Cohen   +6 more
core   +2 more sources

Antineutrophil Cytoplasmic Antibody [PDF]

, 2020
Patrick O'Shea, Daniel Bell, Craig Hacking   +2 more
openaire   +2 more sources

Scavenging of Isolevuglandins Attenuates Neutrophil Migration and Neutrophil Extracellular Trap Formation in Systemic Lupus Erythematosus

ACR Open Rheumatology, Volume 8, Issue 3, March 2026.
Objective Systemic lupus erythematosus (SLE) is an autoimmune disease that affects numerous organs. Neutrophil extracellular traps (NETs) contribute to sterile inflammation and autoantibody generation in SLE. Isolevuglandins (isoLGs) are reactive oxygen species that are formed during NETosis and contribute to chromatin expansion.
Jaya Krishnan, Néstor de la Visitación, Johnson C. Phung, Jonathan M. Williams, Leslie J. Crofford, Matthew Alexander, David M. Patrick, Anna E. Patrick   +7 more
wiley   +1 more source

Neutrophil extracellular traps mediate transfer of cytoplasmic neutrophil antigens to myeloid dendritic cells toward ANCA induction and associated autoimmunity. [PDF]

, 2012
Antineutrophil cytoplasmic antibodies (ANCAs) target proteins normally retained within neutrophils, indicating that cell death is involved in the autoimmunity process. Still, ANCA pathogenesis remains obscure.
Abdgawad, Alcorta, Barbara Cappetti, Bennett, Bianchi, Brinkmann, Carla Guarnotta, Cassatella, Caterina Vitali, Chin, Claudia Chiodoni, Claudio Tripodo, Clayton, Colombo, Cristiana Guiducci, Di Carlo, Dittmar, Donnelly, Drenkard, Falk, Fuchs, Gaipl, Galeazzi, Garcia-Romo, Gilligan, Griffith, Guiducci, Jarius, Kantari, Kessenbrock, Lande, Manolova, Mariella Parenza, Mario P. Colombo, Martinelli, Metzler, Munafo, Nagata, Nathan, Patrizia Casalini, Patry, Potter, Pradhan, Remijsen, Sabina Sangaletti, Sangaletti, Santiago-Raber, Silvia Piconese, Specks, Spronk, Steinman, Tripodo, van der Geld, van Timmeren, Villanueva, Wernick, Witko-Sarsat, Ziegler-Heitbrock   +57 more
core   +1 more source

Association of ANCA associated vasculitis and rheumatoid arthritis: a lesser recognized overlap syndrome [PDF]

, 2015
Background ANCA associated vasculitis (AAV) is an autoimmune disease with significant morbidity and mortality, in which diagnostic delay is associated with worse outcomes. AAV is rarely found in association with other immune mediated diseases.
Draibe, J, Salama, AD
core   +2 more sources

Extracellular Vesicle‐Delivered tRF‐His‐GTG‐1 Reprograms Neutrophil Lipophagy and Triggers Inflammation in COVID‐19

Advanced Science, Volume 13, Issue 13, 3 March 2026.
This study identifies platelet‐derived extracellular vesicles as key immunometabolic regulators in COVID‐19. The delivery of tRF‐His‐GTG‐1 to neutrophils activates TLR8mTOR signaling, disrupts lipophagy, and amplifies NET‐mediated inflammation. Importantly, targeting this axis restores neutrophil homeostasis, offering a potential therapeutic strategy ...
Tsai‐Ling Liao, Po‐Yu Liu, Yi‐Ming Chen, Kuo‐Tung Tang, Hung‐Jen Liu, Der‐Yuan Chen   +5 more
wiley   +1 more source

Eosinophilic fasciitis (Shulman's disease): review and comparative evaluation of seven patients. [PDF]

, 2019
OBJECTIVES: Eosinophilic fasciitis (EF) was described in 1974 by Shulman as a rare fibrosing connective tissue disease of unknown etiology. An undetermined trigger is thought to lead to the degranulation of eosinophils that interact with fibroblasts and
Cimbron, M, Farinha, F, Mendonça, T, Urzal, J   +3 more
core   +1 more source

Exploring the Vasculitis‐Tumors Link: Epidemiological Patterns, Mechanistic Insights, and Clinical Implications

Advanced Science, Volume 13, Issue 14, 9 March 2026.
This review outlines association between vasculitis and malignancies and provides practical value for clinicians in distinguishing primary vasculitis from malignancy‐associated forms and optimizing patient surveillance, improving recognition of tumor‐associated vasculitis to reduce the risk of misdiagnosis, supporting more accurate clinical decision ...
Xiaofei Shi, Zhijiao Li, Xin Ma, Bei Zhang, Xinfeng Wu, Hua Fan, Rongzeng Liu, Hongwei Jiang, Cong‐Qiu Chu   +8 more
wiley   +1 more source

Cardiovascular disease and antineutrophil cytoplasmic antibodies-associated vasculitis: A systematic review

Saudi Journal for Health Sciences
Recent evidence suggests that cardiovascular disease and antineutrophil cytoplasmic antibodies (ANCA)-associated vasculitis (AAV) are interconnected. This investigation aims to examine the epidemiology, potential risk, and cardiovascular events among AAV
Amal H. Mohamed, Nagla Abdalgani
doaj   +1 more source

Emerging concepts in the pathogenesis of antineutrophil cytoplasmic antibody-associated vasculitis. [PDF]

, 2015
PURPOSE OF REVIEW: Antineutrophil cytoplasmic antibodies (ANCAs) remain central to our current understanding of the pathogenesis of ANCA-associated vasculitis (AAV), and this review considers recent developments in the context of four key questions: are ...
Flint, Shaun M, McKinney, Eoin F, Smith, Kenneth GC   +2 more
core