Results 191 to 200 of about 17,492 (243)

Antineutrophil cytoplasmic antibodies

The Lancet, 2006
Much like other autoantibodies (eg, anti-double stranded DNA in systemic lupus erythematosus or antiglomerular basement membrane antibodies in Goodpasture's syndrome), antineutrophil cytoplasmic antibodies (ANCA) have provided doctors with a useful serological test to assist in diagnosis of small-vessel vasculitides, including Wegener's granulomatosis,
X, Bosch, J, Font, E, Mirapeix
openaire   +4 more sources

Antineutrophil cytoplasmic antibodies

American Journal of Medicine, 1992
Antineutrophil cytoplasmic antibodies (ANCA) have been described as sensitive and specific markers for active Wegener's granulomatosis (WG). ANCA in WG produce a characteristic cytoplasmic staining pattern of neutrophils (c-ANCA) and are directed against proteinase 3 (Pr3), a serine protease from the azurophilic granules.
Kallenberg, Cees G. M.   +2 more
openaire   +1 more source

Antineutrophil cytoplasmic antibodies in children

European Journal of Pediatrics, 1998
To define the diagnostic meaning of antineutrophil cytoplasmic antibodies (ANCA) positivity in children, we analysed 1485 consecutive sera sent for routine immunological investigation to our department from January to August 1996. Using this large screening, we identified the most typical clinical disorders associated with ANCA in childhood.
A, Sedivá   +2 more
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Antineutrophil cytoplasmic antibody-associated neutropenia

European Journal of Internal Medicine, 2004
BACKGROUND: Antineutrophil cytoplasmic antibodies (ANCA) can be associated with various disorders. However, their association with neutropenia has never been reported. METHODS: Nine patients with chronic unexplained neutropenia and ANCA were studied. Clinical charts were extensively analyzed and all patients underwent hematological and immunological ...
Paul, Coppo   +7 more
openaire   +2 more sources

Antineutrophil cytoplasmic antibody-associated vasculitis

Current Opinion in Nephrology & Hypertension
Purpose of review This review focuses on latest developments in managing antineutrophil cytoplasmic autoantibody (ANCA)-associated vasculitis (AAV), a systemic autoimmune condition characterized by inflammation and necrosis of small blood vessels due to circulating autoantibodies that target neutrophilic granules.
Raghunandan, Konda   +2 more
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The antineutrophil cytoplasmic antibody–associated vasculitides

The American Journal of Medicine, 2004
Wegener's granulomatosis, microscopic polyangiitis, and Churg-Strauss syndrome are small- to medium-vessel vasculitides linked by overlapping pathology and the presence of antineutrophil cytoplasmic antibodies (ANCA). Commonly referred to as the ANCA-associated vasculitides, these diseases are challenging to diagnose and to treat.
Philip, Seo, John H, Stone
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Testing for antineutrophil cytoplasmic antibodies

Expert Review of Molecular Diagnostics, 2001
The most common reason to request a test for antineutrophil cytoplasmic antibodies (ANCA) is to diagnose Wegener's granulomatosis and microscopic polyangiitis and to monitor inflammatory activity in these diseases. Several retrospective and prospective studies have suggested that the demonstration of ANCA lacks sensitivity and specificity, but these ...
openaire   +2 more sources

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