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Cytomegalovirus-induced severe enterocolitis associated with ANCA-associated vasculitis and diffuse alveolar haemorrhage in a child: a diagnostic and therapeutic dilemma. [PDF]
Ma D +7 more
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Relapsing polychondritis presenting with intractable chronic cough, acute visual disturbance, and hearing loss. [PDF]
Kim H, Kong E.
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[ANCA (antineutrophil cytoplasm antibodies)].
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Antineutrophil cytoplasmic antibodies
The Lancet, 2006Much like other autoantibodies (eg, anti-double stranded DNA in systemic lupus erythematosus or antiglomerular basement membrane antibodies in Goodpasture's syndrome), antineutrophil cytoplasmic antibodies (ANCA) have provided doctors with a useful serological test to assist in diagnosis of small-vessel vasculitides, including Wegener's granulomatosis,
X, Bosch, J, Font, E, Mirapeix
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Antineutrophil cytoplasmic antibodies
American Journal of Medicine, 1992Antineutrophil cytoplasmic antibodies (ANCA) have been described as sensitive and specific markers for active Wegener's granulomatosis (WG). ANCA in WG produce a characteristic cytoplasmic staining pattern of neutrophils (c-ANCA) and are directed against proteinase 3 (Pr3), a serine protease from the azurophilic granules.
Kallenberg, Cees G. M. +2 more
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Antineutrophil cytoplasmic antibodies in children
European Journal of Pediatrics, 1998To define the diagnostic meaning of antineutrophil cytoplasmic antibodies (ANCA) positivity in children, we analysed 1485 consecutive sera sent for routine immunological investigation to our department from January to August 1996. Using this large screening, we identified the most typical clinical disorders associated with ANCA in childhood.
A, Sedivá +2 more
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Antineutrophil cytoplasmic antibody-associated neutropenia
European Journal of Internal Medicine, 2004BACKGROUND: Antineutrophil cytoplasmic antibodies (ANCA) can be associated with various disorders. However, their association with neutropenia has never been reported. METHODS: Nine patients with chronic unexplained neutropenia and ANCA were studied. Clinical charts were extensively analyzed and all patients underwent hematological and immunological ...
Paul, Coppo +7 more
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Antineutrophil cytoplasmic antibody-associated vasculitis
Current Opinion in Nephrology & HypertensionPurpose of review This review focuses on latest developments in managing antineutrophil cytoplasmic autoantibody (ANCA)-associated vasculitis (AAV), a systemic autoimmune condition characterized by inflammation and necrosis of small blood vessels due to circulating autoantibodies that target neutrophilic granules.
Raghunandan, Konda +2 more
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The antineutrophil cytoplasmic antibody–associated vasculitides
The American Journal of Medicine, 2004Wegener's granulomatosis, microscopic polyangiitis, and Churg-Strauss syndrome are small- to medium-vessel vasculitides linked by overlapping pathology and the presence of antineutrophil cytoplasmic antibodies (ANCA). Commonly referred to as the ANCA-associated vasculitides, these diseases are challenging to diagnose and to treat.
Philip, Seo, John H, Stone
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Testing for antineutrophil cytoplasmic antibodies
Expert Review of Molecular Diagnostics, 2001The most common reason to request a test for antineutrophil cytoplasmic antibodies (ANCA) is to diagnose Wegener's granulomatosis and microscopic polyangiitis and to monitor inflammatory activity in these diseases. Several retrospective and prospective studies have suggested that the demonstration of ANCA lacks sensitivity and specificity, but these ...
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