Results 201 to 210 of about 17,492 (243)
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Antineutrophil cytoplasmic antibody-associated vasculitides

Joint Bone Spine, 2007
The identification of antineutrophil cytoplasmic antibodies (ANCA) proved a major breakthrough in the classification, diagnosis, monitoring, and understanding of vasculitides. Vasculitides associated with ANCA selectively affect the small vessels; they include Wegener granulomatosis, microscopic polyangiitis, and Churg-Strauss syndrome.
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Childhood antineutrophil cytoplasmic antibodies associated vasculitides

Current Opinion in Rheumatology, 2014
The purpose of this review is to discuss the most recent published literature in childhood antineutrophil cytoplasmic antibodies (ANCA) associated vasculitides and to identify the important issues arisen in the adult literature. This review will discuss the literature on new treatment regimens and outcome measurements.Antineutrophil cytoplasmic ...
Marinka, Twilt, Susanne, Benseler
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Antineutrophil Cytoplasmic Antibody–Associated Lung Fibrosis

Seminars in Respiratory and Critical Care Medicine, 2018
AbstractPulmonary fibrosis is observed in a substantial number of patients with ANCA-associated vasculitis (AAV), 15% in a recent German series, and may be more frequent in Asian populations. ANCA are usually of anti-MPO specificity and microscopic polyangiitis is the most frequent vasculitis.
Raphael, Borie, Bruno, Crestani
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Antineutrophil cytoplasmic antibodies (ANCA) and vasculitis

Clinical Rheumatology, 1990
The demonstration of autoantibodies to different myeloid lysozomal enzymes has opened a new area for the study of vasculitic syndromes. Autoantibodies producing a granular cytoplasmic staining by IIF (c-ANCA, probably directed to a putative serine protease) are closely associated with Wegener's granulomatosis.
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Antineutrophil Cytoplasmic Antibodies in Diffuse Panbronchiolitis

Respiration, 1999
<i>Background:</i> There are some reports of the coexistence of chronic suppurative lung diseases such as cystic fibrosis and systemic vasculitis. Diffuse panbronchiolitis has the same characteristics as chronic recurrent sinopulmonary infection and respiratory bronchiolitis.
Y, Sugiyama, S, Kitamura
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Antineutrophil Cytoplasmic Antibodies Testing and Interpretation

Clinics in Laboratory Medicine, 2019
The discovery of antineutrophil cytoplasmic antibodies (ANCA) helped establish ANCA-associated vasculitis as a separate and well-defined clinical entity. Its progressive incorporation into the clinical diagnosis algorithms has made ANCA testing a cornerstone immunoassay embedded in the management of ANCA-associated vasculitis.
Hugues, Allard-Chamard, Patrick, Liang
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Clinical value of antineutrophil cytoplasmic antibodies

Current Rheumatology Reports, 2000
This article presents a brief review of the clinical value of antineutrophil cytoplasmic antibodies (ANCA) in the diagnosis and management of patients with various forms of vasculitis. ANCA assay methodology and testing recommendations are reviewed. The patterns of reactivity of ANCA observed by indirect immunofluorescence, the antigens recognized by ...
V, Rus, B S, Handwerger
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Antineutrophil Cytoplasmic Antibodies (ANCAs)

Journal of the American Society of Nephrology
ANCA-associated vasculitis (AAV) is a rare and potentially fatal autoimmune disorder characterized by pauci-immune necrotizing vasculitis affecting small- to medium-sized blood vessels. The pathogenic role of ANCAs in AAV is supported by both clinical and experimental evidence, and when used in the proper clinical setting, ANCA testing is highly ...
Nicole E. Wyatt   +3 more
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Sialadenitis in Antineutrophil Cytoplasmic Antibodies Vasculitis

Journal of The Association of Physicians of India
Granulomatosis with polyangiitis (GPA) is a pauci-immune vasculitis typically involving upper and lower respiratory tract involvement and crescentic glomerulonephritis. Salivary gland involvement in GPA is rare. When it occurs in GPA, it is commonly seen with sinonasal and lung involvement and rarely with renal involvement.
Aditi, Patankar   +3 more
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Sputum Antineutrophil Cytoplasmic Antibodies in Serum Antineutrophil Cytoplasmic Antibody–Negative Eosinophilic Granulomatosis with Polyangiitis

American Journal of Respiratory and Critical Care Medicine, 2019
Eosinophilic granulomatosis with polyangiitis (eGPA) is a small-vessel vasculitis where 40% of patients present with serum antineutrophil cytoplasmic antibodies (ANCAs). We examined the presence and clinical relevance of sputum ANCAs in the serum ANCA- patients with eGPA.ANCA was investigated in matched sputum and blood samples collected from 23 ...
Manali, Mukherjee   +13 more
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