Results 111 to 120 of about 529,151 (288)

Anticardiolipin and antinuclear antibodies in discoid lupus erythematosus--their clinical significance.

, 1988
Fifty-two patients with discoid lupus erythematosus were examined with reference to systemic symptoms and the presence and titre of antinuclear antibody and anticardiolipin antibody were determined.
Mayou, SC, Wojnarowska, F, Lovell, CR, Asherson, RA, Leigh, IM   +4 more
core   +1 more source

Diffuse Skin Sclerosis in a Patient With Lung Cancer

JEADV Clinical Practice, EarlyView.
Anna‐Sophia Leven, Eva Hadaschik, Alpaslan Tasdogan   +2 more
wiley   +1 more source

Antinuclear antibodies in systemic lupus erythematosus

, 2014
Autoantibodies to the three extractable nuclear antigens (ENA),Anti·SSA (Ro), Anti-Srn, Anti·RNP and antinuclear antibodies were determined in 150 patients with SLE.
M. Med (int Med, H. S. Howe, K. Fong
core  

Targeting the NR3C1‐ACSL4 Axis Triggers Ferroptosis to Overcome Radioresistance in Prostate Cancer

Cancer Science, EarlyView.
The glucocorticoid receptor NR3C1 drives prostate cancer radioresistance by upregulating ACSL4. High ACSL4 levels create a lipid metabolic vulnerability. The clinical agent DHA synergizes with ACSL4 to induce lipid peroxidation and ferroptosis, effectively overcoming radioresistance.
Jing Yang, Puyuan Chen, Yawen Zheng, Feiyue Shi, Min Wang, Luwei Xu, Xiaowei Wei, Xiumei Wang   +7 more
wiley   +1 more source

Discoid Lupus Erythematosus in Genital Skin: A Case Report and Review of the Literature

Journal of Cutaneous Pathology, EarlyView.
ABSTRACT Background Discoid lupus erythematosus (DLE) represents the most common variant of chronic cutaneous lupus erythematosus, a skin‐specific autoimmune disorder within the broader lupus erythematosus spectrum Clinically, DLE is characterized by erythematous, scaly plaques with areas of hyperpigmentation.
Ala' Abu‐Dayeh, Daniel Miller, Alessio Giubellino   +2 more
wiley   +1 more source

Immunoglobulin E and systemic lupus erythematosus

Brazilian Journal of Medical and Biological Research, 2004
Systemic lupus erythematosus (SLE) is an autoimmune disease characterized by intense polyclonal production of autoantibodies and circulating immune complexes. Some reports have associated SLE with a Th2 immune response and allergy.
Atta A.M., Sousa C.P., Carvalho E.M., Sousa-Atta M.L.B.   +3 more
doaj  

An Atypical Skin Presentation of Adult‐Onset Still's Disease With Histological Description: A Case Report

Journal of Cutaneous Pathology, EarlyView.
ABSTRACT Adult‐onset Still's disease (AOSD) is an auto inflammatory disorder with a variable clinical presentation, and without a pathognomonic diagnostic test, characterized by high spiking fever, arthralgia/arthritis, a suggestive skin rash, elevated white blood cell count 10 G/L (> 80% neutrophils), elevated ferritin, with glycosylated ferritin < 20%
M. Nordmann, T. Mazza, S. Menzinger, G. Kaya, S. Bogiatzi, S. Vandenberghe‐Dürr, M. Blanchard, J. Stirnemann   +7 more
wiley   +1 more source

Review Article - Antinuclear Antibodies: Clinical Applications

, 2000
One of the common serological hallmarks of autoimmune disorders is the presence of various autoantibodies in the sera of patients affected by these disorders.
A. Wanchu
core   +2 more sources

Systemic lupus erythematosus and nephritis: severe relapse with disappearance of antinuclear antibodies.

, 1980
Exacerbations of systemic lupus erythematosus with active renal disease are almost always associated with high plasma titres of antinuclear factor (ANF) and DNA-binding antibody (anti-ds DNA).
White, Nicholas, Ledingham, JG, Winearls, CG   +2 more
core   +1 more source

Utility of IL‐18 Immunohistochemistry in Distinguishing Dermatomyositis and Lupus Erythematosus in Skin Biopsies

Journal of Cutaneous Pathology, EarlyView.
ABSTRACT Background Distinction of dermatomyositis (DM) and cutaneous lupus erythematosus (LE) in skin biopsies is often difficult due to significant histopathologic overlap. Prior transcriptional analysis has identified upregulation of IL‐18 in DM compared with LE.
Steven M. Hrycaj, Joseph S. Durgin, Johann E. Gudjonsson, J. Michelle Kahlenberg, Gaidaa R. Majari, Carole Bitar, Catherine G. Chung, Rosalynn M. Nazarian, May P. Chan   +8 more
wiley   +1 more source