Results 81 to 90 of about 54,568 (249)

Late onset systemic sclerosis with seronegativity: a rare presentation of an uncommon disease

open access: yesReumatismo, 2019
Systemic sclerosis (SSc) is an uncommon connective tissue disorder characterized by multisystem involvement with fibrosis of skin and internal organs. Antibody formation is one of the hallmarks of SSc.
D. Saxena   +5 more
doaj   +1 more source

Iguratimod alleviated Sjögren's syndrome through regulating macrophage polarization

open access: yesRheumatology &Autoimmunity, EarlyView.
Nonobese diabetic (NOD) mice exhibited characteristic of Sjögren's syndrome (SS), with increased M1 macrophages and deceased M2 macrophages. Iguratimod alleviated SS‐like symptoms and restored balance of macrophage polarization through inhibiting the mitogen‐activated protein kinases pathway in NOD mice.
Junqiao Guo   +7 more
wiley   +1 more source

APPLICATION OF DIFFERENT LABORATORY METHODS FOR ANTINUCLEAR AUTOANTIBODIES INVESTIGATION IN PATIENTS WITH AUTOIMMUNE CONNECTIVE TISSUE DISEASES

open access: yesActa Biomedica Scientifica, 2012
1222 patients with suspicion of different autoimmune connective tissue diseases are investigated. Antinuclear antibodies by indirect immunofluorescence reaction, by methods of ELISA and immunoblotting were determined.
I. A. Pashnina   +3 more
doaj  

Fator antinúcleo na dermatologia Antinuclear factor in dermatology

open access: yesAnais Brasileiros de Dermatologia, 2005
Trata-se de artigo de revisão e atualização sobre a pesquisa dos anticorpos antinucleares, em especial do fator antinúcleo, em que são abordados os aspectos históricos, epidemiológicos, fisiopatogenia, métodos de identificação, suas especificidades e ...
Artur Antônio Duarte
doaj   +1 more source

Predictors of systemic sclerosis patients with interstitial lung disease progression: A retrospective study

open access: yesRheumatology &Autoimmunity, EarlyView.
The final systemic sclerosis patients with interstitial lung disease (SSc‐ILD) progression prediction model was composed of 6 significant risk factors: male, type 2 diabetes mellitus, pericardial effusion, anti‐Ro52, hypoproteinemia, and elevated C‐reactive protein. Our model demonstrated excellent prognostic utility.
Xi Cao   +6 more
wiley   +1 more source

Relationship between autoimmune thyroid antibodies and anti-nuclear antibodies in general patients

open access: yesFrontiers in Endocrinology
BackgroundThere is no doubt that both Hashimoto thyroiditis and Graves’ disease are autoimmune thyroid diseases (AITDs), but the relationship between anti-nuclear antibody (ANA) and AITDs is poorly studied.
Yi Ruan   +11 more
doaj   +1 more source

Systemic sclerosis: current views of its pathogenesis. [PDF]

open access: yes, 2003
Systemic sclerosis (SSc) is an autoimmune disorder of unknown etiology characterized by severe and often progressive cutaneous and visceral fibrosis, pronounced alterations in the microvasculature, and numerous cellular and humoral immune abnormalities ...
Derk, Chris T., Jimenez, Sergio A.
core   +2 more sources

Association of OAS1 rs1051042 polymorphism with genetic susceptibility and clinical phenotypes to systemic lupus erythematosus in a Chinese population

open access: yesRheumatology &Autoimmunity, EarlyView.
OAS1 is an interferon‐induced gene that has been reported to be associated with the susceptibility of some infectious diseases, but there is little data on OAS1 single nucleotide polymorphism (SNP) associated with Systemic lupus erythematosus (SLE).
Xin Huang   +4 more
wiley   +1 more source

Uso do infliximabe e aparecimento sequencial de autoanticorpos e neoplasia em paciente com espondiloartrite Infliximab use and sequential occurrence of autoantibodies and neoplasia in a patient with spondyloarthritis

open access: yesRevista Brasileira de Reumatologia, 2010
O aparecimento de anticorpos antinucleares tem sido relatado após o uso prolongado de anti-TNFs. A emergência de neoplasias linfoproliferativas também tem sido descrita e, com menor frequência, os tumores sólidos.
Ricardo Golmia, Morton Scheinberg
doaj   +1 more source

γδ T cells affect IL-4 production and B-cell tolerance [PDF]

open access: yes, 2014
γδ T cells can influence specific antibody responses. Here, we report that mice deficient in individual γδ T-cell subsets have altered levels of serum antibodies, including all major subclasses, sometimes regardless of the presence of αβ T cells.
Andrew Getahun   +22 more
core   +1 more source

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