Results 81 to 90 of about 54,568 (249)
Late onset systemic sclerosis with seronegativity: a rare presentation of an uncommon disease
Systemic sclerosis (SSc) is an uncommon connective tissue disorder characterized by multisystem involvement with fibrosis of skin and internal organs. Antibody formation is one of the hallmarks of SSc.
D. Saxena+5 more
doaj +1 more source
Iguratimod alleviated Sjögren's syndrome through regulating macrophage polarization
Nonobese diabetic (NOD) mice exhibited characteristic of Sjögren's syndrome (SS), with increased M1 macrophages and deceased M2 macrophages. Iguratimod alleviated SS‐like symptoms and restored balance of macrophage polarization through inhibiting the mitogen‐activated protein kinases pathway in NOD mice.
Junqiao Guo+7 more
wiley +1 more source
1222 patients with suspicion of different autoimmune connective tissue diseases are investigated. Antinuclear antibodies by indirect immunofluorescence reaction, by methods of ELISA and immunoblotting were determined.
I. A. Pashnina+3 more
doaj
Fator antinúcleo na dermatologia Antinuclear factor in dermatology
Trata-se de artigo de revisão e atualização sobre a pesquisa dos anticorpos antinucleares, em especial do fator antinúcleo, em que são abordados os aspectos históricos, epidemiológicos, fisiopatogenia, métodos de identificação, suas especificidades e ...
Artur Antônio Duarte
doaj +1 more source
The final systemic sclerosis patients with interstitial lung disease (SSc‐ILD) progression prediction model was composed of 6 significant risk factors: male, type 2 diabetes mellitus, pericardial effusion, anti‐Ro52, hypoproteinemia, and elevated C‐reactive protein. Our model demonstrated excellent prognostic utility.
Xi Cao+6 more
wiley +1 more source
Relationship between autoimmune thyroid antibodies and anti-nuclear antibodies in general patients
BackgroundThere is no doubt that both Hashimoto thyroiditis and Graves’ disease are autoimmune thyroid diseases (AITDs), but the relationship between anti-nuclear antibody (ANA) and AITDs is poorly studied.
Yi Ruan+11 more
doaj +1 more source
Systemic sclerosis: current views of its pathogenesis. [PDF]
Systemic sclerosis (SSc) is an autoimmune disorder of unknown etiology characterized by severe and often progressive cutaneous and visceral fibrosis, pronounced alterations in the microvasculature, and numerous cellular and humoral immune abnormalities ...
Derk, Chris T., Jimenez, Sergio A.
core +2 more sources
OAS1 is an interferon‐induced gene that has been reported to be associated with the susceptibility of some infectious diseases, but there is little data on OAS1 single nucleotide polymorphism (SNP) associated with Systemic lupus erythematosus (SLE).
Xin Huang+4 more
wiley +1 more source
O aparecimento de anticorpos antinucleares tem sido relatado após o uso prolongado de anti-TNFs. A emergência de neoplasias linfoproliferativas também tem sido descrita e, com menor frequência, os tumores sólidos.
Ricardo Golmia, Morton Scheinberg
doaj +1 more source
γδ T cells affect IL-4 production and B-cell tolerance [PDF]
γδ T cells can influence specific antibody responses. Here, we report that mice deficient in individual γδ T-cell subsets have altered levels of serum antibodies, including all major subclasses, sometimes regardless of the presence of αβ T cells.
Andrew Getahun+22 more
core +1 more source