Results 81 to 90 of about 45,375 (222)
The utility of whole exome sequencing in diagnosing Wilson disease: A case report
JPGN Reports, EarlyView.Abstract Wilson disease (WD) is an autosomal recessive disorder of copper metabolism caused by mutations in the ATP7B gene, resulting in toxic copper accumulation in the body. Diagnosis is typically based on biochemistries, including low serum ceruloplasmin and elevated 24‐h urine copper excretion, with Kayser–Fleischer (KF) rings being a supportive ...
Mihir J. Palan +4 more
wiley +1 more source
Comparative study for detection of antinuclear antibodies by ELISA and Immunoflourescent techniques
, 2014 Background: Antinuclear antibodies frequently arise in the sera of patients with connective tissue disease, including systemic lupus erythematosus, rheumatoid arthritis.
M A B Gamal, Abdulbaset M E Abusetta
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Serial Antinuclear Antibodies Titer in Pleural and Pericardial Fluid
, 2008 The antinuclear antibodies (ANA) test has been a cornerstone of the evaluation of connective tissue disease. The aim of this study was to investigate the diagnostic value of the ANA test in pleural or pericardial effusions of unknown causes.
WANG, DER-YUAN;YANG, PAN-CHYR;YU, CHONG -JEN;KUO, SOW-HSONG +1 more
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Usefulness of studies looking for autoimmunity in patients with spontaneous chronic urticaria
Revista Alergia México, 2015 Background: Chronic spontaneous urticaria (CSU) is a common condition in adults, especially among women; this entity is frequently associated with autoimmune diseases.
María Isabel Rojo-Gutiérrez +4 more
doaj +1 more source
Nephrogenic Systemic Fibrosis: A Rare Contemporary Case After a Decade of Declining Incidence
JEADV Clinical Practice, EarlyView.ABSTRACT Nephrogenic systemic fibrosis (NSF) is a rare fibrosing disorder associated with exposure to gadolinium‐based contrast agents in patients with renal impairment. Although its incidence has markedly declined since the restriction of high‐risk linear gadolinium agents, sporadic cases may still occur.
Marta Sánchez Díaz +5 more
wiley +1 more source
Estimation of sensitivity and specificity of antinuclear antibody by automated indirect immunofluorescence and enzyme-linked immunoassay [PDF]
Medical Laboratory JournalBackground: Immunofluorescence and serology analysis are the most common laboratory methods for diagnosing antinuclear antibodies in autoimmune diseases and are paramount for screening and therapeutic purposes. This study aims to estimate the sensitivity
Mohammadreza Sheikh Sajjadieh +2 more
doaj
Epilepsy and Behavior Case Reports, 2018 Numerous autoantibodies are implicated in the pathogenesis of autoimmune epilepsy. In the past decade, many case series reported the association of glutamic acid decarboxylase 65 (GAD 65) antibodies with epilepsy.
Mohamed AlKhaja +3 more
doaj +1 more source
TRIM Expression and Its Association With Disease Activity in Systemic Lupus Erythematosus
The Kaohsiung Journal of Medical Sciences, EarlyView.ABSTRACT Systemic lupus erythematosus (SLE) is a chronic autoimmune disease with diverse manifestations, including rash, arthritis, and nephritis. Although autoantibodies are a key feature of SLE, their levels often poorly reflect disease severity, suggesting the involvement of additional contributing factors.
Ling‐Ying Lu +8 more
wiley +1 more source
Antinuclear antibodies in systemic lupus erythematosus
, 2014 Autoantibodies to the three extractable nuclear antigens (ENA),Anti·SSA (Ro), Anti-Srn, Anti·RNP and antinuclear antibodies were determined in 150 patients with SLE.
M. Med (int Med, H. S. Howe, K. Fong
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Rheumatology &Autoimmunity, EarlyView.This large‐scale retrospective study of 5778 primary Sjögren's disease (SjD) patients, stratified by diagnostic age, defines a distinct clinical and immunological profile for early‐diagnosed (<45 years) disease. We identified early diagnosis as an independent risk factor for hypergammaglobulinemia and interstitial lung disease, underpinned by a ...
Yuan Ning +7 more
wiley +1 more source