Results 211 to 220 of about 38,829 (239)
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Antiphospholipid antibody syndrome

Current Opinion in Ophthalmology, 2012
Antiphospholipid syndrome is a rare cause of ocular vaso-occlusive disease, but is associated with significant systemic morbidity and mortality. Thus, early diagnosis and treatment is essential.Although the pathophysiology of antiphospholipid syndrome continues to be poorly understood, there has been continued progress with regard to the relationship ...
Paul, Yang   +2 more
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Atherogenic Antiphospholipid Antibodies in Antiphospholipid Syndrome

Annals of the New York Academy of Sciences, 2007
Abstract:  Macrophage uptake of oxidized LDL (oxLDL) plays a critical role in early stages of atherosclerosis. We previously reported that oxLDL forms stable complexes with β2‐glycoprotein I (β2GPI), and that these complexes were frequently present in the sera of patients with systemic lupus erythematosus (SLE) and/or antiphospholipid syndrome (APS ...
Kazuko, Kobayashi   +2 more
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Antiphospholipid antibodies, antiphospholipid syndrome and infections

Autoimmunity Reviews, 2008
Since the association between antiphospholipid antibodies (aPL) and syphilis was first described, many other viral, bacterial and parasitic infections have been shown to induce antiphospholipid antibodies, notably anticardiolipin antibodies (aCL). A review of the literature shows that while aCL occur frequently in viral infections, particularly in HIV (
Damien, Sène   +2 more
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Atherosclerosis, Antiphospholipid Syndrome, and Antiphospholipid Antibodies

Frontiers in Bioscience, 2007
In antiphospholipid syndrome (APS) patients, some antiphospholipid antibodies (APA) are directed against negatively-charged phospholipids, while other APA are specific for phospholipid-proteins such as beta2-glycoprotein I (beta2GPI). Increased levels of oxidized low density lipoproteins (oxLDL) are present in atherosclerosis patients and these ...
Danielle, Nicolo   +2 more
openaire   +2 more sources

Antiphospholipid antibodies and infertility

Human Fertility, 2002
Antiphospholipid antibodies (aPL) are an established cause of recurrent pregnancy loss. As defective embryonic implantation is a common link between unexplained infertility and recurrent miscarriage, interest has focused on the potential relationship between aPL and implantation failure after in vitro fertilization and embryo transfer (IVF-ET).
May, Backos, Raj, Rai, Lesley, Regan
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ANTIPHOSPHOLIPID ANTIBODY SYNDROME

Rheumatic Disease Clinics of North America, 1992
The antiphospholipid syndrome is now well recognized and is separable from SLE, but better quantitation of both the clinical elements and the serologic definitions is still needed. It is likely for autoimmune but not for infection-induced aPL that the antigen is not phospholipid itself but a complex formed by phospholipid and beta 2 glycoprotein I ...
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Pediatric Antiphospholipid Antibodies and Antiphospholipid Syndrome

Seminars in Thrombosis and Hemostasis, 2008
Antiphospholipid syndrome (APS) can occur in children, like adults, with the same diverse spectrum of thrombotic sites but predominately with deep vein thrombosis and stroke. In contrast with adults, however, transient nonthrombogenic antiphospholipid (aPL) antibodies are seen more commonly, usually after childhood infections.
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Antiphospholipid antibody syndrome

Current Treatment Options in Cardiovascular Medicine, 2003
Antiphospholipid antibody syndrome (APS) is a recently defined autoimmune disorder characterized by recurrent vascular thromboses or recurrent pregnancy morbidity; these features are linked to the presence in blood of autoantibodies against negatively charged phospholipids or phospholipid-binding proteins.
Elena, Cucurull   +3 more
openaire   +2 more sources

Antiphospholipid antibodies and the endothelium

Current Rheumatology Reports, 2000
This article reviews current understanding of the relationship between antiphospholipid antibodies and the endothelium. In vitro antiphospholipid antibodies produce endothelial cell activation. Clinical data in this area are scanty and worthy of future research, which could lead to new therapies in the management of antiphospholipid syndrome.
B J, Hunt, M A, Khamashta
openaire   +2 more sources

Antiphospholipid antibodies and pregnancy

Best Practice & Research Clinical Haematology, 2003
Antiphospholipid antibodies, i.e. lupus anticoagulants and anticardiolipin antibodies, are associated with obstetric complications. Fetal death and recurrent spontaneous abortions represent the obstetric criteria of the antiphospholipid syndrome. They occur with similar frequences and have an overall prevalence of 15-20%.
Monica, Galli, Tiziano, Barbui
openaire   +2 more sources

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