Results 91 to 100 of about 2,168,435 (342)

Monoclonal Antibody to Fungal Glucosylceramide Protects Mice against LethalCryptococcus neoformansInfection [PDF]

open access: yesClinical and Vaccine Immunology, 2007
ABSTRACTGlucosylceramides (GlcCer) are involved in the regulation ofCryptococcus neoformansvirulence. In the present study, we demonstrate that passive immunization with a monoclonal antibody to GlcCer significantly reduces host inflammation and prolongs the survival of mice lethally infected withC.
Marcio L, Rodrigues   +7 more
openaire   +2 more sources

Immunity against fungal beta 1,3 glucan carbohydrate in the gastrointestinal tract [PDF]

open access: yes, 2016
Inflammatory Bowel Disease (IBD) is a debilitating, life- long disease that affects about 1.4 millions Americans. Little is known about the pathogenesis of IBD and an effective cure still remains to be discovered.
Feliu, Marianela
core   +1 more source

Consumed by Abdominal Distention

open access: yes
Arthritis Care &Research, EarlyView.
Abimbola Fadairo‐Azinge   +3 more
wiley   +1 more source

Gemella morbillorum Promotes Colorectal Carcinogenesis: LPBDCP‐Mediated Invasion Activates Ras Signaling and Destabilizes p53

open access: yesAdvanced Science, EarlyView.
ABSTRACT Gut microbiota dysbiosis promotes colorectal cancer (CRC) tumorigenesis. A global fecal metagenomic analysis identified Gemella morbillorum as a key contributor to the CRC‐associated microbiota. Fluorescence in situ hybridization revealed that Gemella morbillorum is enriched in CRC tumor tissues compared to adjacent normal tissues.
Zhen Wang   +8 more
wiley   +1 more source

ZZE-Configuration of chromophore ß-153 in C-phycocyanin from Mastigocladus laminosus [PDF]

open access: yes, 1987
The photochemistry of C-phycocyanin has been studied after denaturation in the dark. It shows an irreversible reaction which has characteristics of a Ζ,Ζ,Ε- to Z,Z,Z-isomerization of dihydrobilins. Its amplitude depends on the reaction conditions, with
Bode, W.   +7 more
core   +1 more source

The Transcription Factor FgSge1 Harnesses the SAGA Complex to Activate Mycotoxin Biosynthesis and Fungal Virulence

open access: yesAdvanced Science, EarlyView.
This study reveals the molecular mechanism by which the transcription factor FgSge1 regulates mycotoxin biosynthesis and virulence in Fusarium graminearum. FgSge1 binds to the TAARGTTT cis‐element, enabling self‐activation. It recruits the SAGA complex, promotes histone acetylation, and facilitates jet‐like chromatin remodeling, thereby activating ...
Yueqi Zhang   +6 more
wiley   +1 more source

Development of sensitive polyclonal antibodies against dominant stored wheat grain fungus for its immunological detection

open access: yesJulius-Kühn-Archiv, 2018
Fungal infestation causes deterioration of stored food grains. Most fungal species produce secondary metabolites like aflatoxins which are highly toxic to animals and humans.
Kumari, Rajana, Gosch, Ananta K.
doaj   +1 more source

Antibody-Mediated Protection through Cross-Reactivity Introduces a Fungal Heresy into Immunological Dogma [PDF]

open access: yesInfection and Immunity, 2007
It is hard to believe that only a decade or so ago the question of whether specific antibodies protected against fungal pathogens was considered controversial (for a review, see reference 5). Since the landmark paper by Dromer et al. in 1987 showing that a monoclonal antibody (MAb) to Cryptococcus neoformans polysaccharide was protective against ...
Arturo, Casadevall, Liise-anne, Pirofski
openaire   +2 more sources

Infections with cytomegalovirus and other herpesviruses in 121 liver transplant recipients: Transmission by donated organ and the effect of OKT3 antibodies [PDF]

open access: yes, 1988
One hundred twenty-one adult liver transplant recipients were studied for the incidence, risk factors, and morbidity associated with herpesviruses infections after transplantation. The overall incidence of infection was 59% for cytomegalovirus (CMV), 35%
Armstrong, JA   +7 more
core   +1 more source

Hijacking the Host Clock: A Nematode Effector Antagonizes Soybean Circadian Defense and Translation Control

open access: yesAdvanced Science, EarlyView.
Soybean employs its circadian clock, governed by GmCCA1, to rhythmically defend against soybean cyst nematodes. The pathogen retaliates by secreting the effector Hg4E02, which hijacks the clock to suppress defense and co‐opt the host's translation machinery for nutrient acquisition.
Xingwei Wang   +21 more
wiley   +1 more source

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