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Fungal Infections Potentiated by Biologics.

Infectious Disease Clinics of North America, 2020
Biologic therapies including monoclonal antibodies, tyrosine kinase inhibitors, and other agents represent a notable expansion in the pharmacotherapy armamentarium in treatment of a variety of diseases.
M. Davis, G. Thompson, T. Patterson
semanticscholar   +1 more source

Fatal fungal endocarditis in a patient with primary antibody deficiency

Journal of Clinical Pathology, 2017
Pathogens have well recognised patterns of infections but these rules are often violated in immunocompromised hosts leading to infections by atypical organisms at unexpected sites. While many of the immunodeficiency syndromes could be pinpointed to the molecular level such as X linked agammaglobulinaemia, chronic granulomatous disease and activated ...
Gabriel K Wong   +3 more
openaire   +1 more source

Antibody-mediated protective immunity in fungal infections.

The new microbiologica, 2006
The host response to fungal infection is the result of a complex interaction between the pathogen and the host's innate and adaptive immune system. Cell-mediated immunity is widely considered to be critical for the successful outcome of fungal infections.
MAGLIANI, Valter   +7 more
openaire   +1 more source

Prevalence of fungal complement-fixing antibodies in sarcoidosis.

The American review of respiratory disease, 1977
The prevalence of fungal complement-fixing antibodies in sera from 58 patients with sarcoidosis was determined and compared to complement-fixing antibody titers in 50 sera from a normal control group and 50 antinuclear antibody-positive sera. Sera from 9 patients with sarcoidosis had complement-fixing antibody titers greater than 1:8 to Histoplasma ...
J E, Johnson   +3 more
openaire   +1 more source

Antibody to Fungal Melanin Part of Promising Melanoma Treatment

Microbe Magazine, 2012
A melanin-binding monoclonal antibody carrying radioactive particles damages human melanoma cells in vivo, protects mice implanted with human-derived melanoma tumors, and shows promise in patients with metastatic melanoma, according to Arturo Casadevall of the Albert Einstein College of Medicine in New York. This experimental treatment stems from basic
openaire   +1 more source

Ultra scaledown to predict filtering centrifugation of secreted antibody fragments from fungal broth

Biotechnology and Bioengineering, 2002
AbstractExtracellularly expressed anti–hen egg lysozyme single‐chain antibody fragments (scFv) produced by Aspergillus awamori were recovered using filtering centrifugation. Two filtering centrifuges with 0.5‐ and 30‐L capacities were used to represent laboratory‐ and pilot‐scale equipment, respectively. Critical regime analysis using the computational
N, Boulding   +4 more
openaire   +2 more sources

Production of antibodies to fungal endoglucanase in murine ascitic fluid

Biotechnology Techniques, 1994
Polyclonal antibodies to endoglucanase of the brown-rot fungus Postia placenta were produced in murine ascitic fluid. The mice produced a mean volume of 17.7 mL ascites and a mean reciprocal antibody titer of 419 by ELISA. Anti-endoglucanase antibody inhibited 100 percent of the endoglucanase activity extracted from P. placenta-decayed wood.
openaire   +1 more source

Endemic Fungal Infections in Inflammatory Bowel Disease Associated with Anti-TNF Antibody Therapy

Inflammatory Bowel Diseases, 2013
Patients with inflammatory bowel disease are susceptible to complications from pharmacologic treatment of their disease. Tumor necrosis factor (TNF)-α inhibitors are being used increasingly in the treatment of inflammatory bowel disease and can be associated with adverse events, including common infections, and rarely the development of serious life ...
Miguel E, Ordonez   +2 more
openaire   +2 more sources

Monoclonal Antibodies to Fungal Plant Pathogens: Basic and Applied Aspects

2017
This chapter reviews advances in the study of plant disease brought about by using monoclonal antibodies raised against fungi. It also reviews the use of monoclonal antibodies in plant disease research. Successful detection and quantitation of fungal plant pathogens in seed, plant tissue, and soil has been achieved using polyclonal antibodies in enzyme-
Keith L. Wycoff, Laurence M. Brill
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Killer antibodies in fungal infections

Research in Immunology, 1998
CONTI, Stefania   +6 more
openaire   +2 more sources

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