Results 51 to 60 of about 2,168,435 (342)
TNFα Blockade Inhibits Both Initial and Continued Control of Pulmonary Coccidioides
Frontiers in Cellular and Infection Microbiology, 2022 Tumor necrosis factor alpha (TNFα) is a pluripotent cytokine that is important in many infections, though its role in Coccidioides infection remains poorly understood.
Daniel A. Powell +9 more
doaj +1 more source
Intestinal fungi contribute to development of alcoholic liver disease [PDF]
, 2017 This study was supported in part by NIH grants R01 AA020703, U01 AA021856 and by Award Number I01BX002213 from the Biomedical Laboratory Research & Development Service of the VA Office of Research and Development (to B.S.). K.H.
Ali Keshavarzian +37 more
core +3 more sources
Functionality of the human antibody response to Candida albicans
Virulence, 2021 Candida albicans is a common commensal on human mucosal surfaces, but can become pathogenic, e.g. if the host is immunocompromised. While neutrophils, macrophages and T cells are regarded as major players in the defense against pathogenic C.
Melissa Wich +8 more
doaj +1 more source
Case Report: Invasive Fungal Infection and Daratumumab: A Case Series and Review of Literature
Frontiers in Oncology, 2022 Life expectancy of multiple myeloma (MM) patients has improved in last years due to the advent of anti-CD38 monoclonal antibodies in combination with immunomodulators and proteasome inhibitors.
Francesca Farina +16 more
doaj +1 more source
Anti-fungal Cell Wall β-glucan Antibody in Animal Sera
Nippon Ishinkin Gakkai Zasshi, 2010 beta-Glucan is a major component of the cell walls and pathogen-associated microbial patterns of fungi. We previously reported the presence of an antibody which reacts to beta-glucan, anti-beta-glucan (BG) antibody, in human sera. In livestock and domestic pets, the antibody's response to fungal cell wall beta-glucan is little understood. In this study,
Ken-ichi, Ishibashi +5 more
openaire +3 more sources
Frontiers in Pharmacology, 2019 Fungal infections have aroused much interest over the last years because of their involvement in several human diseases. Immunocompromission due to transplant-related therapies and malignant cancer treatments are risk factors for invasive fungal ...
Tomas Di Mambro +9 more
doaj +1 more source
RNA interference screening reveals host CaMK4 as a regulator of cryptococcal uptake and pathogenesis [PDF]
, 2017 Cryptococcus neoformans , the causative agent of cryptococcosis, is an opportunistic fungal pathogen that kills over 200,000 individuals annually. This yeast may grow freely in body fluids, but it also flourishes within host cells.
Doering, Tamara L +4 more
core +2 more sources
mBioThough a confined or a broad population is exposed respectively to endemic or pandemic infections, in the same environment, some individuals resist the development of infections.
Frédérique Vernel-Pauillac +5 more
doaj +1 more source
Frontiers in Microbiology, 2011 The first work reporting synthesis of glucosylceramide (cerebrin, GlcCer) by yeasts was published in 1930. During approximately 70 years members of this class of glycosphingolipids (GSL) were considered merely structural components of plasma membrane in ...
Leonardo eNimrichter +1 more
doaj +1 more source
mSphere, 2016 Histoplasma capsulatum produces extracellular vesicles containing virulence-associated molecules capable of modulating host machinery, benefiting the pathogen. Treatment of H.
Ludmila Matos Baltazar +6 more
doaj +1 more source