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Antibodies: monoclonal and polyclonal
Animal Biotechnology, 2020Anchal Singh, Ayushi Mishra, Anju Verma
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Deimmunization of Monoclonal Antibodies
2008Immunogenicity is a major limitation to therapy with certain monoclonal antibodies and proteins. A major driver for immunogenicity is the presence of human T-cell epitopes within the protein sequence which can activate helper T-cells resulting in the sustained production of antibodies and neutralization of the therapeutic effect.
Laura J. Crompton +3 more
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Monoclonal antibodies in haematology
Blood Reviews, 1989The development of methods for the production of monoclonal antibodies is having an important impact in the field of immunohaematology. Four separate areas are implicated. First, there is the use of monoclonal antibodies in blood transfusion, where antibodies within the ABO, Rh, Lewis, P, MN, Kell and Lutheran systems are available.
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Monoclonal Antibody TfR Monoclonal Antibody
Monoclonal Antibodies in Immunodiagnosis and Immunotherapy, 2017openaire +2 more sources
Radiolabeling of Monoclonal Antibodies
2000Radiolabeling of monoclonal antibodies (mAbs) is often one of the principal methods for the in vitro and in vivo assessment of these reagents, whether this is determining the affinity of a new reagent, preparing for preclinical testing, or clinically for diagnostic or therapeutic use.
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