Results 11 to 20 of about 2,156,550 (237)

Antibody targeting of mutant calreticulin in myeloproliferative neoplasms

Journal of Cellular and Molecular Medicine, 2023
AbstractMutations in calreticulin are one of the key disease‐initiating mutations in myeloproliferative neoplasms (MPN). In MPN, mutant calreticulin translates with a novel C‐terminus that leads to aberrant binding to the extracellular domain of the thrombopoietin receptor, MPL.
Frederike Kramer, Ann Mullally
openaire   +2 more sources

Antiphospholipid antibodies and the risk of thrombosis in myeloproliferative neoplasms

Open Life Sciences, 2023
Abstract The morbidity and mortality of BCR-ABL-negative myeloproliferative neoplasia (MPN) patients is highly dependent on thrombosis that may be affected by antiphospholipid antibodies (aPLA) and lupus anticoagulant. Our aim was to evaluate the association of the aPLA together with platelet receptor glycoprotein (GP) Ia/IIa c.807C>T
Dambrauskienė Rūta, Gerbutavičius Rolandas, Rudžianskienė Milda, Paukštaitienė Renata, Vitkauskienė Astra, Skrodenienė Erika, Remeikienė Diana, Zaborienė Inga, Juozaitytė Elona   +8 more
openaire   +3 more sources

Paraneoplastic Neurological Syndromes of the Central Nervous System: Pathophysiology, Diagnosis, and Treatment

Biomedicines, 2023
Paraneoplastic neurological syndromes (PNS) include any symptomatic and non-metastatic neurological manifestations associated with a neoplasm. PNS associated with antibodies against intracellular antigens, known as “high-risk” antibodies, show frequent ...
Luca Marsili, Samuel Marcucci, Joseph LaPorta, Martina Chirra, Alberto J. Espay, Carlo Colosimo   +5 more
doaj   +1 more source

Investigating the association between neoplasms and MOG antibody-associated disease

Frontiers in Neurology, 2023
IntroductionThe association of myelin oligodendrocyte glycoprotein (MOG) antibody associated disease (MOGAD) and tumors has seldom been reported. We aim to investigate the occurrence of tumors in a cohort of patients with MOGAD and to describe their clinical features, in addition to previously reported cases.MethodsWe retrospectively identified ...
Milena Trentinaglia, Alessandro Dinoto, Sara Carta, Vanessa Chiodega, Sergio Ferrari, Vincenzo Andreone, Giorgia Teresa Maniscalco, Giorgia Teresa Maniscalco, Sara Mariotto   +8 more
openaire   +4 more sources

Infiltration of plasma cells in colorectal adenocarcinoma associated with autoimmune encephalitis

Annals of Clinical and Translational Neurology, 2021
Paraneoplastic autoimmune encephalitis (PAE) represents a group of rare neurological syndromes associated with neoplastic diseases. Here, we report a case that multiple anti‐neuronal antibodies were present in a patient with PAE who developed both small ...
Yaqing Shu, Dan He, Xiaoyu Ma, Jianfang Li, Haotian Wu, Chen Chen, Zhengqi Lu, Frank Petersen, Wei Qiu, Xinhua Yu   +9 more
doaj   +1 more source

Coccidiomycosis infection of the patella mimicking a neoplasm - two case reports. [PDF]

, 2014
BackgroundCoccidioidomycosis is an endemic fungal infection in the southwestern of United States. Most infections are asymptomatic or manifest with mild respiratory complaints. Rare cases may cause extrapulmonary or disseminated disease.
Calvert, George, Hanrahan, Christopher J, Jones, Kevin B, Li, Yi-Chen, Randall, Robert Lor   +4 more
core   +1 more source

Immune myopathies with perimysial pathology: Clinical and laboratory features [PDF]

, 2018
ObjectiveImmune myopathies with perimysial pathology (IMPP) have a combination of damage to perimysial connective tissue and muscle fiber necrosis, more prominent near the perimysium.
Bucelli, Robert C, Pestronk, Alan
core   +2 more sources

Lyme Disease and Associated NMDAR Encephalitis: A Case Report and Literature Review

Neurology International, 2021
We present a case of a patient with positive N-methyl-D-aspartate receptor (NMDAR) IgG antibodies in their serum and cerebrospinal fluid (CSF) associated with neuroborreliosis.
Natalja Predkele, Jānis Mednieks
doaj   +1 more source

A33 shows similar sensitivity to but is more specific than CDX2 as an immunomarker of colorectal carcinoma [PDF]

, 2017
Aims: CDX2 is widely used as a sensitive and specific immunomarker for colorectal carcinoma (CRC) but neither this sensitivity nor specificity is absolute. This study is the first known comparison of CDX1 and A33 against CDX2 as immunomarkers for CRC.
Adamczyk, Lukasz A., Cullen, Jayne, Evans, Shanna, Oien, Karin A., Oniscu, Anca, Wong, Newton A.C.S.   +5 more
core   +1 more source

Blastic Plasmacytoid Dendritic Cell Neoplasm: State of the Art and Prospects

Cancers, 2019
Blastic plasmacytoid dendritic cell neoplasm (BPDCN) is an extremely rare tumour, which usually affects elderly males and presents in the skin with frequent involvement of the bone-marrow, peripheral blood and lymph nodes. It has a dismal prognosis, with
M. Sapienza, A. Pileri, E. Derenzini, F. Melle, G. Motta, S. Fiori, A. Calleri, N. Pimpinelli, V. Tabanelli, S. Pileri   +9 more
semanticscholar   +1 more source