Claudin 18.2 is a target for IMAB362 antibody in pancreatic neoplasms [PDF]
International Journal of Cancer, 2013 The majority of pancreatic neoplasms are characterized by a generally lethal progress within a short period of time after primary diagnosis and the mortality of patients is expected to increase further. Due to lack of efficient screening programs and moderate response to treatments, novel compounds for treatment are needed. We investigated the CLDN18.2
Wöll, Stefan +6 more
openaire +3 more sources
Enfermedad de motoneurona asociada a procesos neoplásicos: una revisión de casos
Galicia Clínica, 2021 Introduction: Association between Motor Neuron Disease (MND) and neoplastic processes is rarely described. It is unclear whether MND occurs as a paraneoplastic syndrome.
Raquel Rocha +4 more
doaj +1 more source
Differential Diagnoses of Systemic Mastocytosis in Routinely Processed Bone Marrow Biopsy Specimens: A Review [PDF]
, 2010 Diagnosis of systemic mastocytosis (SM) is mainly based on the morphological demonstration of compact mast cell infiltrates in various tissue sites. In almost all patients such infiltrates are detected in the bone marrow.
Horny, H. -P., Sotlar, K., Valent, P.
core +1 more source
Journal of Medical Case Reports, 2012 Introduction An unprovoked thombotic event in a patient is cause for further evaluation of an underlying hypercoaguable state. The investigation should include a thorough search, including checking for a variety of known inherited and acquired ...
Pemmaraju Naveen +4 more
doaj +1 more source
Frontiers in Bioscience-Landmark, 2021 Objective: To describe the clinical features, laboratory data, treatment, and outcomes of anti-N-methyl-d-aspartate (NMDAR) encephalitis in Chinese patients.
Qianhui Xu +12 more
doaj +1 more source
C1q acts in the tumour microenvironment as a cancer-promoting factor independently of complement activation [PDF]
, 2015 Complement C1q is the activator of the classical pathway. However, it is now recognized that C1q can exert functions unrelated to complement activation.
Agostinis, C +9 more
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CYTOKINES AND HISTOPATHOLOGIC PATTERN OF MALIGNANT NEOPLASMS IN GASTROINTESTINAL CANCER
Медицинская иммунология, 2014 The patients with gastrointestinal cancer exhibit high contents of TNFα, IL-1β, IL-2, IL-6, IL-8, IFNγ, IL-1Ra and increased levels of anti-IFNα antibodies. Significant correlations are detected between histopathological parameters of the tumors, and the
A. I. Autenshluss +7 more
doaj +1 more source
High frequency of inadequate test requests for antiphospholipid antibodies in daily clinical practice [PDF]
, 2011 Background: We have empirically noted that many physicians routinely request anti-phospholipid antibodies (aPL) without a correct clinical indication. The aim of this study was to evaluate retrospectively whether aPL testing at our Thrombosis Centre was ...
Barcellona D +3 more
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Clinical picture and treatment of myasthenia gravis in the adult population
Journal of Education, Health and Sport, 2022 Introduction and purpose: Myasthenia gravis (MG, myasthenia gravis ) is a classic example of an autoimmune disease caused by antibodies against acetylcholine receptors ( AChR) , muscle-specific kinase (MuSK) or other AChR-related proteins in the ...
Tomasz Swatko +4 more
doaj +1 more source
Is porto sinusoidal vascular disease to be actively searched in patients with portal vein thrombosis? [PDF]
, 2019 Porto sinusoidal vascular liver disease (PSVD) and portal vein thrombosis (PVT) are distinct vascular liver diseases characterized, respectively, by an intrahepatic and a prehepatic obstacle to the flow in the liver portal system. PVT may also occur as a
D'Amati, G. +4 more
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