Results 61 to 70 of about 1,730,056 (192)

Immune Consequences of Metabolic Syndrome and Its Treatment: A Cytokine Perspective

Immunology, EarlyView.
Peripheral blood mononuclear cells (PBMCs) from individuals with metabolic syndrome (MetS) who were not using glucose‐and/or lipid lowering medication (GLLM) exhibited a broader cytokine production profile after in vitro antigen‐specific stimulation than PBMCs from individuals with MetS using such medications and from healthy donors.
Isabela Ghetti Macedo Isaac, Carolina do Prado Servian, Fernanda de Oliveira Feitosa de Castro, João Lucas Lima Calandrini de Azevedo, Ronaldo Moraes Preto, Miriam Leandro Dorta, Daniela Espíndola Antunes, Simone Gonçalves Fonseca   +7 more
wiley   +1 more source

Canine Leishmaniosis in Italy: Geospatial Trends and Incidence, a Shift in Epidemiological Approach

Zoonoses and Public Health, EarlyView.
ABSTRACT Introduction Canine leishmaniosis (CanL) has shown a marked geographic expansion in Italy, progressively affecting central and northern regions previously considered non‐endemic. Laboratory‐based prevalence estimates remain informative in well‐designed surveys; however, prevalence derived from diagnostic submissions may be influenced by study ...
Federica Bruno, Germano Castelli, Eugenia Oliveri, Gaetano Oliva, Mariele De Santi, Claudia La Rocca, Ornella Melideo, Marco Ripamonti, Francesco La Russa, Maria Liliana Di Pasquale, Antonella Galante, Roberto Hamel, Giorgio Schiera, Marzio Cometa, Silvia Scibetta, Stefano Reale, Fabrizio Vitale   +16 more
wiley   +1 more source

Comparison of indirect and modified agglutination tests for detection of antibodies to Toxoplasma gondii in domestic cats

Journal of Veterinary Diagnostic Investigation, 2019
Toxoplasma gondii is a protozoan parasite with worldwide distribution. The accurate detection of this zoonotic agent in cats and other hosts has public health importance. Blood samples from 89 domestic cats were tested for antibodies to T. gondii using 2
Susan M. Fernandes, Paula Brilhante-Simões, T. Coutinho, L. Cardoso, J. Dubey, A. P. Lopes   +5 more
semanticscholar   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, Volume 20, Issue 8, Page 1913-1932, August 2026.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source

Trans-sialidase delivered as a naked DNA vaccine elicits an immunological response similar to a Trypanosoma cruzi infection

Brazilian Journal of Medical and Biological Research, 1999
Trypanosoma cruzi, the protozoan parasite that causes Chagas' disease, does not synthesize sialic acid, but expresses a trans-sialidase (TS) that catalyzes the transfer of sialic acid from host glycoconjugates to the parasite surface.
F. Costa, V.L. Pereira-Chioccola, M. Ribeirão, S. Schenkman, M.M. Rodrigues   +4 more
doaj   +1 more source

Unusual MRI features in a case of presumed canine tick‐borne meningoencephalomyelitis

Veterinary Record Case Reports, Volume 14, Issue 3, August 2026.
Abstract A 7‐year‐old, standard, wire‐haired dachshund presented with quickly progressive multifocal central nervous system signs, which localised to the brainstem and cervical myelopathy, including reduced cervical and thoracic limb muscle tone and withdrawal reflexes. Magnetic resonance imaging revealed bilateral, approximately symmetric, T2‐weighted
Jon Prager, Alex Smith, Hélène Vandenberghe   +2 more
wiley   +1 more source

Seroprevalence of Toxoplasma gondii IgG and IgM antibodies and associated risk factors in women of child-bearing age in Njinikom, NW Cameroon

BMC Research Notes, 2016
Toxoplasmosis is a widely distributed zoonotic disease, caused by the protozoan parasite Toxoplasma gondii. T. Infections can result in stillbirths, abortions or congenital defects during pregnancy, as well as toxoplasmic encephalitis in HIV/AIDS ...
Elvis Chongsi Wam, L. F. Sama, I. Ali, W. Ebile, Lucy Agyingi Aghangu, C. Tume   +5 more
semanticscholar   +1 more source

Chemokines in Alzheimer's Disease: Early Defence, Late Damage and the Impact of Sex and Infection

Basic &Clinical Pharmacology &Toxicology, Volume 139, Issue 2, August 2026.
ABSTRACT Chemokines constitute a versatile signalling network maintaining homeostasis and glia–neuron communication in the healthy brain but become progressively dysregulated during aging and Alzheimer's disease (AD). This review examines how chemokine systems transition from tightly regulated homeostatic signals to drivers of chronic neuroinflammation
Blanca I. Aldana, Kristine Freude
wiley   +1 more source

Anticorpos anti-Neospora caninum em bovinos de leite do sudoeste do estado do Paraná

Arquivo Brasileiro de Medicina Veterinária e Zootecnia, 2010
Since November 2007 until May 2009, 1,778 serum samples of cattle from dairy herds of the Southwest of Paraná State, Brazil, were used for search of anti-Neospora caninum antibodies. The frequency of seropositive animals, assessed by IFAT, was 24.2% (431/
G Camillo, G Cadore, A.S Cezar, G Toscan, P Bräunig, L.A Sangioni, F.S.F Vogel   +6 more
doaj   +1 more source

Vectors and Vector‐Borne Diseases: Biology, Epidemiology and Integrated Control Strategies

Journal of Applied Entomology, Volume 150, Issue 7, Page 990-1015, August 2026.
ABSTRACT Vector‐Borne Diseases (VBDs), transmitted by arthropods such as mosquitoes, ticks, fleas and sandflies, represent a significant threat to global health. These diseases can be caused by a variety of pathogens, including bacteria, viruses, protozoa, and helminths.
Roberta Rinaldi, Carmen Scieuzo, Federica De Stefano, Luca Masucci, Patrizia Falabella   +4 more
wiley   +1 more source