Results 11 to 20 of about 1,730,056 (192)

Monoclonal Antibodies for Protozoan Infections: A Future Reality or a Utopic Idea? [PDF]

Frontiers in Medicine, 2021
Following the SARS-CoV-2 pandemic, several clinical trials have been approved for the investigation of the possible use of mAbs, supporting the potential of this technology as a therapeutic approach for infectious diseases. The first monoclonal antibody (
Silvia Stefania Longoni, Natalia Tiberti, Zeno Bisoffi, Zeno Bisoffi, Chiara Piubelli   +4 more
doaj   +4 more sources

Seroprevalence rates of antibodies againstLeishmania infantum and other protozoan and rickettsial parasites in dogs [PDF]

Revista Brasileira de Parasitologia Veterinária, 2013
Canine visceral leishmaniasis (CVL) is caused by the protozoan Leishmania infantum, which infects dogs and humans in many regions of Brazil. The present study involved an indirect fluorescent antibody test (IFAT) to analyze L.
Silvana de Cássia Paulan, Aline Gouveia de Souza Lins, Michely da Silva Tenório, Diogo Tiago da Silva, Hilda Fátima de Jesus Pena, Rosangela Zacarias Machado, Solange Maria Gennari, Wilma Aparecida Starke Buzetti   +7 more
doaj   +5 more sources

Antibodies to protozoan variable surface antigens induce antigenic variation

bioRxiv, 2022
Abstract The genomes of most protozoa encode families of variant surface antigens, whose mutually exclusive changes in expression allow parasitic microorganisms to evade the host immune response 1,2 .
Albano H. Tenaglia, Lucas A. Luján, Diego N. Ríos, Victor Midlej, Paula A. Iribarren, Cecilia R. Molina, M. Agustina Berazategui, Alessandro Torri, Alicia Saura, Damián O. Peralta, Macarena Rodríguez-Walker, Elmer A. Fernández, Juan P. Petiti, Marianela C. Serradell, Pablo R. Gargantini, Vanina E. Alvarez, Wanderley de Souza, Hugo D. Luján   +17 more
openaire   +2 more sources

Surface antigenic change during differentiation of a parasitic protozoan, Leishmania mexicana: Identification by monoclonal antibodies. [PDF]

Proceedings of the National Academy of Sciences, 1982
The fusion of SP2/0 myeloma cells with spleen cells from mice immunized with Leishmania mexicana amazonensis promastigotes produced hybridoma clones. Indirect immunofluorescent antibody assay with live leishmanias showed that the monoclonal antibody 6H12 recognized only the antigens bound to the surface of L. mexicana amazonensis promastigotes. It also
Fong, D, Chang, K
openaire   +3 more sources

Antibodies to variable surface antigens induce antigenic variation in the intestinal parasite Giardia lamblia

Nature Communications, 2023
The genomes of most protozoa encode families of variant surface antigens. In some parasitic microorganisms, it has been demonstrated that mutually exclusive changes in the expression of these antigens allow parasites to evade the host’s immune response ...
Albano H. Tenaglia, Lucas A. Luján, Diego N. Ríos, Cecilia R. Molina, Victor Midlej, Paula A. Iribarren, María A. Berazategui, Alessandro Torri, Alicia Saura, Damián O. Peralta, Macarena Rodríguez-Walker, Elmer A. Fernández, Juan P. Petiti, Marianela C. Serradell, Pablo R. Gargantini, Tim Sparwasser, Vanina E. Alvarez, Wanderley de Souza, Hugo D. Luján   +18 more
doaj   +2 more sources

Serological status of mares in parturition and the levels of antibodies (IgG) against protozoan family Sarcocystidae from their pre colostral foals

Veterinary Parasitology, 2014
Protozoa from the family Sarcocystidae are agents of reproductive and neurological disorders in horses. The transmission of these protozoa may occur via horizontal or vertical means, and the frequency and potential of the later is not fully elucidated in horses.
Pivoto, Felipe Lamberti, Macêdo Junior, Arlindo Gomes de, da Silva, Murilo Vieira, Ferreira, Flávia Batista, Silva, Deise Aparecida Oliveira, Pompermayer, Endrigo, Sangioni, Luis Antônio, Mineo, Tiago Wilson Patriarca, Vogel, Fernanda Silveira Flores   +8 more
openaire   +3 more sources

Passive immunization of channel catfish (Ictalurus punctatus) against the ciliated protozoan parasite Ichthyophthirius multifiliis by use of murine monoclonal antibodies

Infection and Immunity, 1996
Fish acquire immunity against the ciliated protozoan parasite Ichthyophthirius multifiliis following sublethal infection. The immune response includes the elaboration of humoral antibodies against a class of abundant surface membrane proteins referred to as immobilization antigens (i-antigens).
T L, Lin, T G, Clark, H, Dickerson
openaire   +3 more sources

B-Cell Response during Protozoan Parasite Infections

Journal of Parasitology Research, 2012
In this review, we discuss how protozoan parasites alter immature and mature B cell compartment. B1 and marginal zone (MZ) B cells, considered innate like B cells, are activated during protozoan parasite infections, and they generate short lived plasma ...
María C. Amezcua Vesely, Daniela A. Bermejo, Carolina L. Montes, Eva V. Acosta-Rodríguez, Adriana Gruppi   +4 more
doaj   +2 more sources

Immunization with Leishmania tarentolae-derived norovirus virus-like particles elicits high humoral response and stimulates the production of neutralizing antibodies

Microbial Cell Factories, 2021
Background Noroviruses are a major cause of epidemic and sporadic acute non-bacterial gastroenteritis worldwide. Unfortunately, the development of an effective norovirus vaccine has proven difficult and no prophylactic vaccine is currently available ...
Mirosława Panasiuk, Karolina Zimmer, Anna Czarnota, Katarzyna Grzyb, Magdalena Narajczyk, Grażyna Peszyńska-Sularz, Sabina Żołędowska, Dawid Nidzworski, Lilit Hovhannisyan, Beata Gromadzka   +9 more
doaj   +2 more sources

Toxoplasma gondii and Neospora caninum antibodies in goats in the Czech Republic

Veterinární Medicína, 2012
Toxoplasma gondii is zoonotic protozoan parasite that causes infections in many vertebrate species. The present study determined the seroprevalence of T. gondii and N. caninum in goats from the Czech Republic.
E. Bartova, K. Sedlak
doaj   +2 more sources