Results 111 to 120 of about 1,714,748 (310)

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

FEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana, Avigail Yariv, Tal Oppenheim, Hadar Amartely, Dana Reichmann, Oded Livnah   +5 more
wiley   +1 more source

Risk factors for Marburg hemorrhagic fever, Democratic Republic of the Congo. [PDF]

, 2003
We conducted two antibody surveys to assess risk factors for Marburg hemorrhagic fever in an area of confirmed Marburg virus transmission in the Democratic Republic of the Congo.
Roth, Cathy, Ksiazek, T. G., Grein, Thomas, Bausch, Daniel G, Kond\ue9, Kader M., Ben Tugume, Modeste L. Libande, Pirard, Patricia, Pierre E. Rollin, Tugume, B., Colebunders, Robert, Bausch, Daniel G., Muyembe-Tamfum, Jean-Jacques, Olinda, L. L., Rodier, G. R., Matthias Borchert, Kondé, Kader M, Talarmin, A., Ksiazek, Thomas G, Borchert, M., Rollin, P. E., Daniel G. Bausch, Pirard, P., Bausch, D. G., Rollin, Pierre E, Thomas G. Ksiazek, Rodier, Guénaël R, Swanepoel, R., Ksiazek, Thomas G., Swanepoel, Robert, Kader M. Kondé, Campbell, P., Campbell, Patricia, Thomas Grein, Libande, Modeste L, Grein, T., Muyembe-Tamfum, J. J., Robert Colebunders, Robert Swanepoel, Jean-Jacques Muyembe-Tamfum, Patricia Pirard, Oyewale Tomori, Patricia Campbell, Tomori, Oyewale, Cathy Roth, Loku L. Olinda, Tugume, Ben, Colebunders, R., Talarmin, Antoine, Roth, C., Libande, M. L., Bertherat, E., Libande, Modeste L., Guénaël R. Rodier, Pirad, Patricia, Olinda, Loku L., Antoine Talarmin, Kondé, K. M., Rollin, Pierre E., Eric Bertherat, Tomori, O., Borchert, Matthias, Bertherat, Eric, Olinda, Loku L, Rodier, Gu\ue9na\uebl R.   +64 more
core   +1 more source

Identification of (20R)‐protopanaxadiol from Panax ginseng as a novel anti‐SARS‐CoV‐2 compound

FEBS Open Bio, EarlyView.
We established a noninfectious BAC‐based SARS‐CoV‐2 replicon that enables antiviral screening under BSL‐2 conditions. Using this platform, we screened 373 food‐derived compounds and identified (20R)‐protopanaxadiol from Panax ginseng as a novel inhibitor of SARS‐CoV‐2 RNA replication, highlighting the value of safe replicon systems for antiviral ...
Midori Takeda, Natsue Maezono, Rina Uchikoshi, Nobuyuki Kato, Masanori Ikeda   +4 more
wiley   +1 more source

Virus-neutralizing monoclonal antibody expressed in milk of transgenic mice provides full protection against virus-induced encephalitis [PDF]

, 2001
Neutralizing antibodies represent a major host defense mechanism against viral infections. In mammals, passive immunity is provided by neutralizing antibodies passed to the offspring via the placenta or the milk as immunoglobulin G and secreted ...
Pewe, L, John Webster, Whitelaw, C B, Andreas F. Kolb, Perlman, S, Siddell, S G, Stanley Perlman, C. Bruce A. Whitelaw, Stuart G. Siddell, Webster, J, Kolb, A F, Lecia Pewe   +11 more
core   +1 more source

Cattle develop neutralizing antibodies to rotavirus serotypes which could not be isolated from faeces of symptomatic calves [PDF]

, 1991
Neutralizing antibodies against 10 serotypes of rotavirus were measured in sera from different age groups of German cattle. Only five of 143 sera did not neutralize heterologous serotypes.
Sidoti, Josette, Eichhorn, Werner, Snodgrass, David, Büssow, Harald, Rohwedder, Angela   +4 more
core   +1 more source

Viral antibodies in bovine fetuses in Argentina

Research in Veterinary Science, 1993
In order to establish the prevalence of viral infections of the bovine fetus in Argentina, a serological survey for antibodies against viral agents currently affecting cattle in this country was conducted. Antibodies against foot-and-mouth disease virus (FMDV), bovine herpesvirus-1 (BHV-1), bovine leukaemia virus (BLV), bovine rotavirus (BRV), bovine ...
Pinto, G.B., Hawkes, P., Zabál, O., Ulloa, E., Lager, I.A., Weber, E.L., Schudel, A.A.   +6 more
openaire   +2 more sources

Protocol for quantifying miRNA trafficking across the endosomal membrane

FEBS Open Bio, EarlyView.
An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh, Kamalika Mukherjee, Suvendra N. Bhattacharyya   +2 more
wiley   +1 more source

From passive protection to lasting immunity: the potential vaccinal effect of antiviral monoclonal antibodies

International Journal of Infectious Diseases
Objectives: Monoclonal antibodies are becoming integral to prophylactic, therapeutic, and curative strategies against acute as well as chronic viral infections.
Sofia Sedó-Nicolaisen, Therese Nordby Larsen, Jesper Damsgaard Gunst, Ole Schmeltz Søgaard   +3 more
doaj   +1 more source

Cell surface CD11c as a neutrophil aging marker molecule

FEBS Open Bio, EarlyView.
Cell surface CD11chi neutrophils were more aged and had better phagocytic function than CD11c−/lo neutrophils. Transcriptomic analysis of CD11chi neutrophils and CD11c−/lo neutrophils in pediatric population showed that the most difference was seen in infants.
Sophia Koutsogiannaki, Fahd Alhamdan, Erik Malm, Marie Bermudez, Samuel Y. Kim, Koichi Yuki   +5 more
wiley   +1 more source