Results 271 to 280 of about 2,860,326 (352)

SARS-CoV-2 mRNA vaccines confer protection in diet-induced obese mice despite altered immune cell profiles in the lung. [PDF]

Sci Rep
Lee KS, Boehm DT, Miller-Stump OA, Rader NA, Cooper M, Cyphert HA, Sen-Kilic E, Barbier M, Damron FH.   +8 more
europepmc   +1 more source

From Lab to Market: Paper‐Based CRISPR Diagnostics and Commercialization Pathways

Advanced Sensor Research, EarlyView.
Paper‐based CRISPR diagnostics represents one of the most widely commercialized CRISPR assay technologies, yet challenges remain for broader point‐of‐care use. Abstract The global health landscape is continually challenged by infectious diseases that can swiftly escalate into pandemics, underscoring the need for rapid, accurate, and cost‐effective ...
Selen Dalgan, Qingshan Wei
wiley   +1 more source

Acute Bickerstaff Brainstem Encephalitis in a Middle-Aged Male: Diagnostic Challenges and Therapeutic Responses. [PDF]

Cureus
Bawwab A, Snoubar I, Hajjeh O, Khatib L, Aiti D.   +4 more
europepmc   +1 more source

Label‐Free, Sensitive, and Direct Detection of Cardiac Troponin Biomarkers Using Frequency‐Locked Microring Resonators

Advanced Sensor Research, EarlyView.
A deployable, chip‐integrated approach to the detection of heart attack biomarkers is demonstrated using silicon photonic microring resonators combined with microfluidics. By applying the Pound–Drever–Hall frequency locking technique, sensor signals are measured with improved signal‐to‐noise ratio, applying this to real‐time, selective readouts.
Evan Diamandikos, Tetsuya Shimogaki, Crispin Szydzik, Peter Thurgood, Luke H. Broadley, Sonya Palmer, Guanghui Ren, Thach G. Nguyen, Cesar S. Huertas, Arnan Mitchell   +9 more
wiley   +1 more source

A new attenuated and highly immunogenic orthopoxvirus vaccine protects against mpox in mice and macaques. [PDF]

NPJ Vaccines
Xu F, Huang Y, Hou Y, Xie Y, Huang B, Zhao F, Gao Z, Chen C, Wang J, Mei S, Hu Y, Wang L, Wei L, Zhang J, Li N, Cong Z, Ma J, Zhu L, Chen T, Lu J, Wei Q, Tan W, Xue J, Guo F.   +23 more
europepmc   +1 more source

Compact Multichannel Plasmonic Device for Rapid and Versatile Inflammatory Biomarker Analysis

Advanced Sensor Research, EarlyView.
A multichannel plasmonic biosensor has been developed for the simultaneous detection of up to four inflammatory biomarkers relevant to sepsis diagnostics. Its performance has been optimized, and analytical validation has been conducted for the detection in diluted serum, highlighting its potential for clinical applications.
Juliana Fátima Giarola, Patricia Ramirez‐Priego, M.‐Carmen Estevez, Laura M. Lechuga   +3 more
wiley   +1 more source

Anti-pA137R antibodies exacerbate the pathogenicity of African swine fever virus in pigs. [PDF]

J Virol
Zhai H, Gao Y, Zhu Y, Hou Q, Wan N, Wang T, Li S, Zhao D, Qiu H-J, Li Y.   +9 more
europepmc   +1 more source

Mechanical Interactions Impact the Functions of Immune Cells and Their Application in Immunoengineering

Advanced Therapeutics, EarlyView.
This review covers the mechanical forces experienced by immune cells through cell–cell and cell–extracellular matrix interactions and how these forces influence their receptors and functions. These relationships between forces and cellular functions can be exploited using engineering techniques to modify the physical properties of materials for novel ...
Yu‐Chang Chen, Nghi M. Tran, Kyle H. Vining   +2 more
wiley   +1 more source

Research Progress on the Application of Neutralizing Nanobodies in the Prevention and Treatment of Viral Infections. [PDF]

Microorganisms
Duan Q, Ai T, Ma Y, Li R, Jin H, Chen X, Zhang R, Bao K, Chen Q.   +8 more
europepmc   +1 more source

Microphysiological Systems in Cancer Research: Advancing Immunotherapy through Tumor Microenvironment‐Integrated Organ‐On‐Chip Models

Advanced Therapeutics, EarlyView.
Emerging microphysiological systems reproduce the spatial, biochemical, and cellular complexity of the tumor microenvironment, surpassing 2D cultures and murine models. By integrating patient‐derived tumors, perfusable vasculature, and immune trafficking, these organ‐on‐chip platforms reveal mechanisms of immune evasion, predict therapeutic responses ...
Fabiana Moresi, Francesco Noto, Jyothsna Vasudevan, Xavier Bisteau, Giulia Adriani, Andrea Pavesi   +5 more
wiley   +1 more source