Results 211 to 220 of about 89,831 (244)

IL‐2 Free Expansion of T Cells with Immunofilaments

Advanced Healthcare Materials, EarlyView.
Ratio and density of stimulatory αCD3 and αCD28 mAb on immunofilaments (IF) influence T cell expansion, cytokine production, and effector phenotype. Moreover, IL‐2 supplementation is not necessary with optimal performing IFs, which leads to simpler culture conditions, and negative side effects of IL‐2 supplementation are reduced.
Marjolein Schluck, Lea Weiss, René Classens, Carl G. Figdor, Roel Hammink   +4 more
wiley   +1 more source

Supervisory signals are intriguingly high in even simple features for predicting anticancer effect of antibody drug conjugates. [PDF]

Brief Bioinform
Nagpal S.
europepmc   +1 more source

Targeting the ARRDC3–DRP1 Axis via hUMSC‐Derived Exosomal CRYAB for Neuroprotection in Cerebral Ischemia/Reperfusion Injury

Advanced Healthcare Materials, EarlyView.
Intranasally administered hUMSC‐derived exosomes modulate the CRYAB–ARRDC3–Drp1 axis, alleviating mitochondrial dysfunction and ferroptosis, enhancing neuronal survival, reducing oxidative stress, and promoting functional recovery in ischemia‐reperfusion injury, offering a promising therapeutic strategy for ischemic stroke.
Rong ji, Zengyu Zhang, Zhuohang Liu, Kaicheng Yang, Xueyu Mao, Min Chu, Yong Wang, Jing Zhao   +7 more
wiley   +1 more source

Determinants of sensitivity to HER2-targeted antibody drug conjugates in urothelial cancer. [PDF]

Nat Commun
Chen Z, Tang X, Eichholz JE, Mcpherson A, Thomas J, Nagar K, Rustgi N, Christin JR, Kuo F, Gao S, Jiang H, Luo J, Ostrovnaya I, Basar M, Pietzak E, Coleman JA, Berger MF, de Stanchina E, Shah SP, Mohibullah N, Aggen DH, Rosenberg JE, Chandarlapaty S, Shen MM, Al-Ahmadie H, Iyer G, Kim K, Solit DB.   +27 more
europepmc   +1 more source

Pharmacokinetics of FK 506 in transplant patients [PDF]

, 1991
Abu-Elmagd, K, Alessiani, M, Flowers, J, Fung, J, Jain, A, Krajak, A, Lever, J, Mehta, S, Starzl, TE, Todo, S, Venkataramanan, R, Warty, VS, Zuckerman, S   +12 more
core  

Smart Catheters for Diagnosis, Monitoring, and Therapy

Advanced Healthcare Materials, EarlyView.
This study presents a comprehensive review of smart catheters, an emerging class of medical devices that integrate embedded sensors, robotics, and communication systems, offering increased functionality and complexity to enable real‐time health monitoring, diagnostics, and treatment. Abstract This review explores smart catheters as an emerging class of
Azra Yaprak Tarman, Samiha Ahmed, Majed Othman Althumayri, Megan Guy, Darlenne Chavez Lugo, Frances S. Ligler, George T. Ligler, Rahmi Oklu, Hiroshi Kawahira, Michael J. McShane, Jun Kameoka, Jonathan Bova, Hatice Ceylan Koydemir   +12 more
wiley   +1 more source

Editorial: Antibody-drug conjugates in solid and hematologic malignancies. [PDF]

Front Immunol
Saleh K, Raman A, Zanoni M.
europepmc   +1 more source

Patient‐Derived 3D Bioprinted Cardiac Organoid Constructs Reveal Key Pathological Features of Duchenne Muscular Dystrophy

Advanced Healthcare Materials, EarlyView.
Patient‐derived cardiac organoids reveal key features of Duchenne muscular dystrophy cardiomyopathy, including apoptosis, oxidative stress, calcium handling defects, and mechanical remodeling. By integrating organoids into alginate–gelatin bioprinted constructs, disease phenotypes are organized into scalable 3D cardiac tissues displaying extracellular ...
Vittoria Marini, Margalida Campaner Socias, Andreas Dimopoulos, Lorenza Rinvenuto, Enrico Pozzo, Diana Stalkopf, Angelo Serafini, Sara Morri, Ashley Wang, Rita La Rovere, Yoke Chin Chai, Sveva Bollini, Geert Bultynck, H. Llewelyn Roderick, Ioannis Papantoniou, Maurilio Sampaolesi   +15 more
wiley   +1 more source

Immuno-OncologyThe adverse event of interstitial lung disease in patients treated with antibody-drug conjugates. [PDF]

Oncologist
Fang N, Wang X, Xu Z, Zhan H, Wang Y, Zhao B, Huang H, Lin M.   +7 more
europepmc   +1 more source