Results 231 to 240 of about 89,831 (244)

Advances in antibody-drug conjugates for urothelial carcinoma treatment. [PDF]

Cancer Biol Med
Wei J, Tang B, Yan X, Li J, Zhou L, Li S, Xu H, Sheng X.   +7 more
europepmc   +1 more source

Paracrine Factor Local Gradient‐Generating System for Engineering Perfusable Vascularized Hepatocyte Tissues with Perfusion‐Induced Proliferation

Advanced Healthcare Materials, EarlyView.
A paracrine factor local gradient (PFLG)‐generating system enables microvessel penetration across 3D hepatocyte tissues. The resulting vascularized constructs recapitulate hepatic sinusoidal hepatocyte—endothelial contact architecture and enhance hepatic functions in vitro.
Yen‐Hsiang Huang, Tadahiro Yamashita, Ryo Sudo   +2 more
wiley   +1 more source

Characterisation of mAb104 Antibody-Drug Conjugates Targeting a Tumour-Selective HER2 Epitope. [PDF]

Cancers (Basel)
Parakh S, Huynh N, Osellame LD, Cao DD, Rigopoulos A, Gloria B, Guo NY, Scott FE, Liu Z, Gan HK, Scott AM.   +10 more
europepmc   +1 more source

Nano‐Engineered Titanium Implants Loaded With Gingival Fibroblasts‐Derived Microvesicles Enhance Early Osseointegration And Soft Tissue Attachment In Vivo

Advanced Healthcare Materials, EarlyView.
Our study showed that human primary gingival fibroblast–derived microvesicles on nano‐engineered titanium implants promote early osseointegration and soft‐tissue attachment in vivo. ABSTRACT Titanium dental implants require both reliable osseointegration and peri‐implant soft tissue seal formation to ensure long‐term success. While osseointegration has
Pingping Han, Chun Liu, Anjana Jayasree, Kamil Sokolowski, Andrew Liaw, Dingbin Liu, Carlos Salomon, Karan Gulati, Ryan SB Lee, Baoxin Huang, Sašo Ivanovski   +10 more
wiley   +1 more source

Mechanisms of resistance to antibody-drug conjugates in cancer therapy: molecular basis and therapeutic strategies. [PDF]

Cancer Drug Resist
Hao Y, Song Z.
europepmc   +1 more source

Engineering Extracellular Vesicle Production Through Magnetic Ion Channel Activation for Bone Regeneration

Advanced Healthcare Materials, EarlyView.
Magnetic Ion Channel Activation (MICA) enables remote stimulation of mechanosensitive ion channels using functionalised magnetic nanoparticles, enhancing extracellular vesicle (EV) biogenesis is pre‐osteoblasts. MICA desrived EVs exhibit typical nano‐vesicular characteristics but display superior pro‐osteogeneic activity, promoting mesenchymal stem ...
Afeesh Rajan Unnithan, Kenny Man, Kritika, Lee A. Gethings, Christopher J. Hughes, Alicia Keenan, Liam Heaney, Sophie C. Cox, Owen G. Davies, Alicia J. El Haj   +9 more
wiley   +1 more source

Targeted therapies for urothelial carcinoma: From FGFR inhibitors to next‑generation antibody-drug conjugates (Review). [PDF]

Int J Oncol
Du J, Shen H, Zeng T, Liu W, Xie Y.
europepmc   +1 more source

Meflin is a druggable target using antibody-drug conjugates in progressive osteosarcoma. [PDF]

Oncogene
Esaki N, Sakoda T, Ando R, Miyai Y, Iida T, Mizutani Y, Yoshida M, Hara Y, Matsuyama M, Kobayashi T, Shiraki Y, Mii S, Ichikawa J, Kawasaki T, Manabe S, Sakai T, Nishida Y, Takahashi M, Enomoto A.   +18 more
europepmc   +1 more source

Evaluating the efficacy and safety of antibody-drug conjugates in non-small cell lung cancer: a systematic review and meta-analysis. [PDF]

BMC Cancer
Zhang L, Jia H, Niu B.
europepmc   +1 more source